Adlina 5mg Tablet

✔️ Uses of Adlina 5mg Tablet

• Type 2 Diabetes Mellitus

✔️ How does Adlina 5mg Tablet work?

Adlina 5mg Tablet boosts insulin production and decreases the production of glucagon, a substance that prompts the liver to produce more sugar. This combined action effectively regulates blood sugar levels.

✔️ Side Effects of Adlina 5mg Tablet

• Hypoglycaemia (low blood glucose levels)
• Upper respiratory tract infection
• Nasopharyngitis (infection of the nose and throat with a common cold)
• Headache

✔️ Quick Suggestions:

• Linagliptin should be taken at the same time every day since this helps you remember to take it.
• It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
• Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremors, and anxiety.
• Be careful while driving or operating machinery until you know how Linagliptin affects you.
• Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.

✔️ Indication

Adlina 5mg Tablet is used for the treatment of type 2 diabetes mellitus as an adjunct to diet and exercise to improve blood glucose levels.

✔️ Pharmacology

Linagliptin improves glycemic control in individuals with type 2 diabetes mellitus. It functions as a DPP-4 (dipeptidyl peptidase-4) inhibitor, preventing the degradation of incretin hormones like GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). This leads to increased levels of active incretin hormones, stimulating insulin release from pancreatic beta (β) cells in response to glucose levels and decreasing the release of glucagon from pancreatic alpha (α) cells in the bloodstream.

✔️ Dosage & Administration of Adlina 5mg Tablet

Take Adlina 5mg Tablet once daily. If taken with metformin, maintain the metformin dosage while administering linagliptin concurrently. When combined with sulfonylurea, consider a lower dose of sulphonylurea to reduce the risk of hypoglycemia. No dosage adjustment is needed for patients with renal impairment. Linagliptin can be taken with or without food at any time of the day. TAdlina 5mg Tablet is not recommended for use in children and adolescents (under 18 years of age). 

Guidelines for using Adlina 5mg Tablet:

• Consume the tablet in the prescribed dose and duration as instructed by your doctor.
• Swallow the tablet whole with a glass of water; do not cut, break, or chew it.
• It can be taken with or without food.
• Take it at a consistent time for the best results.
• Do not exceed the prescribed dose.
• In case of an overdose, inform your doctor or seek medical attention.
• If you miss a dose, take it as soon as you remember. If the next dose is approaching, skip the missed dose. Do not double the dose to compensate for a missed one; never take two doses in one day.

✔️ Interaction

Adlina 5mg Tablet 10's interacts with several types of medications. These include heart condition drugs (digoxin), diuretics (furosemide), steroids (budesonide), antibiotics (rifampin), anti-epileptic drugs (phenytoin, topiramate, lamotrigine), heart-related chest medicine (ranolazine), beta-blocker medications (metoprolol, propranolol), glaucoma eye drops (timolol), insulin, and other antidiabetic medicines.

Regarding food interactions, excessive consumption of alcoholic beverages while using Adlina 5mg Tablet 10's may increase the risk of a serious condition called Lactic Acidosis. Therefore, it's important to avoid alcohol while taking this medication. Additionally, if you are taking St. John's wort, a natural remedy for depression, it's advisable to inform your doctor.

Lastly, there are potential interactions between Adlina 5mg Tablet 10's and certain medical conditions. These interactions could occur if you have heart problems, high triglyceride levels, pancreatitis, gallstones, alcoholism, or kidney problems. It's crucial to communicate any pre-existing medical conditions to your doctor before starting this medication.

✔️ Contraindications

If you are allergic to linagliptin or any other component of Adlina 5mg Tablet.

✔️ Pregnancy & Lactation

Linagliptin tablets fall under Pregnancy Category B, which indicates that there are limited adequate studies conducted on pregnant women. Therefore, the use of Linagliptin during pregnancy should only be considered if deemed absolutely necessary by a healthcare provider. The potential benefits must be carefully weighed against potential risks to the fetus.

The excretion of Linagliptin in breast milk is not well established. Therefore, if you are a breastfeeding mother, it is advised to consult your doctor before using Linagliptin to assess the potential risks and benefits for both you and your baby.

✔️ Precautions & Warnings

• If you are allergic to Adlina 5mg Tablet 10's or any of its components, it's important to avoid its use. Before starting Adlina 5mg Tablet 10's, inform your doctor if you are pregnant or breastfeeding.
• Prolonged use of Adlina 5mg Tablet 10's could potentially lead to acute pancreatitis and severe kidney problems. Be cautious of the risk of hypoglycemia (low blood sugar) when combining Adlina 5mg Tablet 10's with other anti-diabetic agents or insulin. Your doctor may need to adjust the dosage accordingly.
• In some cases, severe allergic reactions like anaphylaxis, angioedema (skin swelling), and skin conditions such as Stevens-Johnson syndrome have been reported in patients taking Adlina 5mg Tablet 10's.
• It's worth noting that Adlina 5mg Tablet 10's has not been established as safe or effective for use in individuals under 18 years of age. Patients on digoxin (a heart medication) should be closely monitored if they are also taking Adlina 5mg Tablet 10's, as there can be severe drug interactions.
• Lastly, Adlina 5mg Tablet 10's is not suitable for patients with type 1 diabetes or for treating diabetic ketoacidosis. It's important to adhere to your doctor's guidance and recommendations when considering or using this medication.

✔️ Storage Conditions

Keep away from light and heat in a dry location. Keep out of children's reach.