Actose 30mg Tablet

✔️ Uses of Actose 30mg Tablet

• Type 2 Diabetes Mellitus

✔️ How does Actose 30mg Tablet work?

Pioglitazone in Actose 30mg Tablet works by helping the body make better use of the insulin it produces.

✔️ Side Effects of Actose 30mg Tablet

• Upper respiratory tract infection
• Headache
• Fracture of bones
• Muscle pain
• Stuffy nose
• Sore throat
• Low blood sugar levels (hypoglycemia)
• Bloody and Cloudy urine
• Painful urination
• Swelling of face, lips, eyelids, tongue, hands and feet
• Irregular heartbeat
• Weight gain

✔️ Quick Suggestions:

• Fill half your plate with starchy veggies, a quarter with proteins, and the remaining quarter with whole grains.
• Eat at regular intervals; avoid long gaps between meals or snacks.
• Monitor blood sugar levels regularly, especially during fluctuations.
• Aim for 150 minutes of moderate-intensity and 15 minutes of high-intensity exercise per week.
• Replace refined carbs with whole grains, and increase fruits, veggies, and fiber-rich foods.
• Reduce saturated fat; opt for omega-3 fatty acid-containing oils for cooking.
• Manage stress through mindfulness, yoga, or meditation to control blood sugar changes.
• Choose low-fat dairy products for consumption.
• Maintain normal blood pressure (120/80) to reduce cardiovascular risk.
• Continue taking the prescribed medication even if blood sugar seems controlled.
• Opt for short, frequent meals to avoid prolonged fasting; carry candies or glucose for hypoglycemia symptoms.
• Inform your physician about underlying conditions before starting the medication.
• Avoid alcohol consumption while on the medication to prevent hypoglycemia and lactic acidosis.
• Aim to quit smoking and reduce intake of carbohydrate-rich foods.

✔️ Indication of Actose 30mg Tablet

• Actose 30mg Tablet is used to manage high blood sugar in type II Diabetes Mellitus.
• It addresses cases where the body struggles to effectively use insulin to transport sugar from the blood to cells.
• The medicine enhances the body's insulin response, aiding blood sugar level control.
• It also reduces sugar production in the liver to further regulate blood sugar.

✔️ Pharmacology

Pioglitazone is a medication containing pioglitazone, belonging to the thiazolidinedione class of anti-diabetic drugs. Its mechanism relies on the presence of insulin. Pioglitazone lessens insulin resistance in the body, both peripherally and hepatically. This leads to improved clearance of glucose-dependent on insulin and reduced production of glucose by the liver. Additionally, it enhances lipid metabolism by activating the proliferative peroxisome activating gamma receptor (PPARγ).

✔️ Dosage & Administration of Actose 30mg Tablet

• Pioglitazone can be taken once daily, with or without meals.
• Diabetes management should be tailored individually.
• For initial insufficient control by diet/exercise, start Pioglitazone monotherapy at 15 mg or 30 mg daily.
• If inadequate response, the dose may be increased to 45 mg daily.
• For an inadequate response to monotherapy, consider combination therapy.
• No placebo-controlled studies used over 30 mg daily.
• Take Actose 30mg Tablet as prescribed by the doctor.
• Do not break, crush, or chew; swallow whole with water.
• Take it consistently at the same time daily.
• Incorporate a low-sugar diet and exercise for maximum benefits.
• Monitor blood sugar levels regularly during treatment.
• Keep sugar candy handy to manage sudden low blood sugar.

Overdose:

• Seek immediate medical help for low blood sugar symptoms or overdose suspicion (dizziness, shakiness, confusion, anxiety, palpitations, etc).

Missed Dose:

• Take missed Actose 30mg Tabletas soon as remembered.
• If close to the next dose, skip and follow the regular schedule.
• Don't double the dose to compensate for missing one.

✔️ Interaction

Individual responses to drugs vary. Before starting any medication, consult your doctor to assess potential interactions.

Interaction with Alcohol:

• No specific description was provided.
• Advice: Avoid alcohol while using Actose 30mg Tablet to prevent heightened side effects.

Interaction with Medicine:

• Gatifloxacin
• Gemfibrozil
• Insulin injection

Disease Interactions:

• Bladder Cancer: Caution is advised due to the higher bladder cancer risk.
• Anaemia: Use with care if you have anaemia, as Actose 30mg Tablet may reduce haemoglobin and haematocrit levels.

Food Interactions:

• No information is available.

Lab Interactions:

• No information is available.

This list doesn't encompass all possible drug interactions. Consult your doctor regarding interactions related to the medications you're taking.

✔️ Contraindications

Actose 30mg Tablet should not be used in cases of:

• Hypersensitivity (allergic reaction).
• Type 1 diabetes mellitus.
• Symptomatic or history of heart failure.
• Diabetic ketoacidosis.
• Children under 18 years of age.
• During lactation.

✔️ Pregnancy & Lactation

Pregnancy:

• Pioglitazone lacks sufficient well-controlled studies in pregnant women.
• Its use during pregnancy is only advised if potential benefits outweigh potential fetal risks.

Lactation:

• The secretion of pioglitazone in human milk is unknown.
• As many drugs are passed through breast milk, lactating women should avoid using pioglitazone.

✔️ Precautions & Warnings

• Regularly monitor liver enzymes.
• Verify history of heart failure and MI.
• Confirm the incidence of bladder cancer.
• Avoid use in elderly patients. V. Restrict continuous use to one year.
• Use only on Specialist's advice.
• Risk of hypoglycemia with insulin or oral hypoglycemics.
• Watch for edema, congestive heart failure, hepatic dysfunction, jaundice, and anemia.
• Premenopausal, anovulatory women may experience ovulation.
• Monitor liver function and glycaemic control.
• Avoid during pregnancy.
• Caution with oral contraceptives/hormonal replacement therapy due to arterial disease risk in diabetics.
• Cease treatment if ALT >3 times the upper limit or jaundice appears.

✔️ Storage Conditions

Store Actose 30mg Tablet in a cool and dry place, protected from direct sunlight, moisture, and heat. Keep it away from children and pets. Do not use expired or damaged medicines. Discard unused medicine properly. Do not flush it in the toilet or throw it into the drain.