Dosage: Combination rapid-onset (faster than regular insulin) and intermediate-acting insulins in fixed dose.
Adult: Dosage should be individualised and adjusted based on patient's glycaemic response. Usual range: 0.5-1 Unit/kg/day.
Side effects: Adverse events commonly associated with human insulin therapy include the following: Allergic reactions. Injection site reaction, lipodystrophy, pruritus, rash, lipoatrophy, hypokalaemia, blurred vision. Hypoglycaemia, insulin resistance.
Precautions: Pregnancy (insulin requirements tend to fall during the 1 st trimester, increase during the 2nd and 3rd) and lactation. Regular monitoring of HbAlc and blood glucose concentrations. Caution with increased insulin requirements: Fever, hyperthyroidism, trauma, infection, surgery