Losucon 1mg Tablet

Uses of Losucon 1mg Tablet

• Type II Diabetes Mellitus

How does Losucon 1mg Tablet work?

This drug lowers blood glucose by stimulating the release of insulin from pancreatic beta cells.

Side Effects of Losucon 1mg Tablet

• Low blood sugar levels (hypoglycemia)
• Dizziness
• Headache
• Nausea
• Flu-like symptoms
• Allergic skin reaction
• Anaemia
• Jaundice
• Weight gain

Quick Suggestions:

• Losucon 1mg Tablet is an anti-diabetic medicine. It is used for the management of type 2 diabetes mellitus by lowering blood sugar levels. It contains glimepiride as the active ingredient.
• It is recommended to take this tablet at the same time every day to maintain consistent levels of the medication in your system for optimal results.
• Along with taking Losucon 1mg Tablet, it is essential that you do certain lifestyle modifications like exercising regularly, walking, avoiding smoking, and drinking alcohol.
• It is also advised to have a balanced diet with adequate fruits and vegetables for good control of your blood sugar levels.
• Keep a check on your blood sugar levels regularly.
• Before starting Losucon 1mg Tablet, inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding and about your detailed medical history.
• Weight gain, low blood sugar, hunger, dizziness, and nausea/vomiting may occur in some individuals with the use of this medicine. Inform your doctor if these effects bother you or do not go away.
• You should avoid driving or operating heavy machinery if you experience drowsiness, unconsciousness, or confusion after using Losucon 1mg Tablet.
• Talk to your doctor if you have kidney or liver disease.
• If you miss a dose of Losucon 1mg Tablet, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and take the next dose at the regular time.

Indication

Glimepiride is prescribed for the following conditions:

• It is prescribed as an adjunct to diet and exercise for individuals with non-insulin-dependent (Type II) diabetes mellitus (NIDDM) whose elevated blood sugar levels cannot be adequately managed through diet and exercise alone.
• Glimepiride can be used in combination with metformin if the response to diet, exercise, and either Glimepiride or metformin alone is insufficient to achieve proper glycemic control.
• It is also approved for use alongside insulin to lower blood glucose levels in individuals with hyperglycemia that is unmanageable through diet, exercise, and oral hypoglycemic medication alone.
• However, combining Glimepiride with insulin increases the risk of hypoglycemia (low blood sugar levels).

Pharmacology

Glimepiride is a sulfonylurea anti-diabetic medication that lowers blood glucose levels. Glimepiride's principal mode of action appears to be based on increasing the release of insulin from active pancreatic beta cells. Glimepiride works in tandem with glucose to increase beta cell sensitivity to physiological glucose stimulation, resulting in insulin production. Glimepiride's action may also be influenced by extrapancreatic effects such as reduced baseline hepatic glucose production, enhanced peripheral tissue sensitivity to insulin, and glucose absorption. A single dosage of Glimepiride has a 24-hour hypoglycemic effect in non-fasting diabetic individuals.

Dosage & Administration of Losucon 1mg Tablet

Adult Dose:

For individuals with Type 2 diabetes mellitus, the usual adult dose of Losucon 1mg Tablet (Glimepiride) is as follows:

• Initial dose: 1-2 mg daily.
• The dosage can be increased gradually by 1-2 mg at intervals of 1-2 weeks.
• Maintenance dose: 4 mg daily.
• The maximum dose should not exceed 6 mg daily.

For elderly individuals:

• Initial dose: 1 mg once daily.

For those with severe hepatic impairment:

• Losucon 1mg Tablet is contraindicated.

Child Dose:

The safety and efficacy of Losucon 1mg Tablet in children have not been established.

Renal Dose:

For individuals with renal impairment:

• Initial dose: 1 mg orally once a day.
• The dose can be adjusted based on fasting blood glucose levels.

For those with severe renal impairment:

• Losucon 1mg Tablet is contraindicated.

Administration:

Take Losucon 1mg Tablet preferably after meals or as instructed by your physician. Swallow the tablet with a glass of water. Avoid crushing or chewing the tablet.

Your doctor will determine the appropriate dosage and duration of therapy based on factors such as your age, body weight, and medical condition. Do not discontinue the use of Losucon 1mg Tablet without consulting your doctor's advice.

Interaction

Losucon 1mg Tablet interacts with various substances:

Drug-Drug Interactions: Losucon 1mg Tablet may interact with Vitamin D3, Vitamin C, Vitamin B12, antidiabetic drugs (liraglutide, rosuvastatin, dapagliflozin, metformin, glyburide, insulin, canagliflozin, sitagliptin, empagliflozin), blood pressure-lowering drugs (furosemide, atorvastatin), painkillers (aspirin, ibuprofen, naproxen), and blood thinners (clopidogrel, warfarin).

Drug-Food Interactions: Losucon 1mg Tablet should not be taken with Fish Oil (omega-3 polyunsaturated fatty acids) and alcohol. Alcohol consumption can impact the blood sugar-lowering effect of Losucon 1mg Tablet 50's.

Drug-Disease Interactions: Individuals with liver or kidney dysfunction, heart diseases, low blood sugar, G6PD deficiency, and electrolyte imbalances (such as low sodium levels in the blood) should avoid using Losucon 1mg Tablet.

Contraindications

Do not use Losucon 1mg Tablet if you have:

An allergy to Glimepiride, Sulfonylureas, Sulfonamides, or any other ingredients present in Losucon 1mg Tablet.

Type 1 diabetes.

Symptoms such as fatigue, nausea, frequent urination, and muscle stiffness, could be indicative of diabetic ketoacidosis.

Severe kidney or liver disease.

Pregnancy & Lactation

Glimepiride should not be used during pregnancy. Instead, insulin is recommended for managing blood sugar levels in pregnant individuals. If you are considering pregnancy, it's important to inform your doctor, who may advise switching to insulin treatment.

The consumption of Glimepiride, along with breastfeeding, could pose risks to the nursing infant. As a precaution, nursing mothers should avoid using Glimepiride. This might require a transition away from breastfeeding or a complete cessation of breastfeeding.

Precautions & Warnings

Before using Losucon 1mg Tablet, it's important to inform your doctor if you are in the process of healing from an injury, has recently undergone surgery, or are experiencing sources of stress such as fever or infections. Contact your doctor as adjustments to your care might be necessary during these times.

If you have a significant kidney or liver disease, if you are pregnant, breastfeeding, or planning to become pregnant, consult your doctor before taking Losucon 1mg Tablet.

Avoid taking Losucon 1mg Tablet if you are allergic to sulpha drugs, glimepiride, or any other anti-diabetic medications. Additionally, individuals with a deficiency of glucose 6-phosphate dehydrogenase (G6PD) should also avoid using this medication.

For patients with heart disease, it's advisable to consult a doctor before taking Losucon 1mg Tablet as it could potentially worsen the existing heart condition.

Refrain from taking Losucon 1mg Tablet concurrent with oral contraceptives, as it may lead to increased blood sugar levels. Conversely, when taking Losucon 1mg Tablet alongside painkillers like aspirin or ibuprofen, it might result in lowered blood sugar levels.

Storage Conditions

Losucon 1mg Tablet does not require any special storage conditions. Try to keep it out of the reach of children and pets.