Cortan 20mg | Prednisolone Medicine | View Uses, Interaction | ePharma
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Cortan 20mg Tablet

Generic: Prednisolone

Type: Tablet

Pack Size: 10 Pcs

Prednisolone is used to treat inflammatory and auto-immune conditions such as:

  • Allergies (including severe allergic reactions)
  • Inflammation (affecting lungs including asthma, blood vessels & heart, bowel and kidney, muscles and joints including rheumatoid arthritis, eye/nervous system)
  • Skin conditions, infections, and cancers (such as leukemia, lymphoma, and myeloma)
  • To prevent organ rejection after transplantation
  • To boost steroid levels when the body is unable to make enough natural steroids on its own.
  • To treat high calcium levels in the body

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Discount Price: ৳ 58.31
MRP: ৳ 62.7 7% Off

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Description:

Cortan 20mg Tablet contains Prednisolone, which is a corticosteroid medication. As you mentioned, it is used in the treatment of various inflammatory and autoimmune conditions, such as severe allergies, asthma, rheumatoid arthritis, skin conditions, and certain infections and cancers.

Cortan 20mg Tablet is also prescribed to prevent organ rejection after transplantation and to supplement steroid levels in cases where the body is unable to produce sufficient natural steroids. Additionally, it can be used to address high calcium levels, which may cause symptoms like stomach pain, nausea, bone pain, and muscle weakness.

However, there are certain precautions and contraindications associated with Cortan 20mg Tablet. It is not recommended for patients with fungal infections or those who have recently received live vaccinations. Before taking this medication, it is important to inform your doctor about any existing infections, underactive thyroid gland, seizures, myasthenia gravis, diabetes, high blood pressure, heart failure, or liver or kidney disease.

Special care should be taken when using Cortan 20mg Tablet during pregnancy and breastfeeding. It is also advised to consult a doctor before administering this medication to children and adolescents under 18 years of age.

Like any medication, Cortan 20mg Tablet can cause side effects. The most common ones include infections, signs of low potassium levels (such as constipation and fast heartbeat), signs of increased blood sugar and urine sugar levels (such as increased thirst and frequent urination), high blood pressure, thinning of the skin, and impaired wound healing.

It is crucial to consult your doctor before starting or discontinuing Cortan 20mg Tablet and to report any concerning side effects experienced during the course of treatment. Your doctor will provide guidance specific to your medical condition and monitor your progress accordingly.

Safety Advices


Alcohol
UNSAFE

It is advisable that you consult your doctor regarding this as the medicine can have serious side effects when consumed with alcohol. Consulting with the doctor can help you avoid serious implications.


Pregnancy
CONSULT YOUR DOCTOR

It is important for pregnant women to avoid this medication as much as possible and consume it only if there are no other alternatives. It may cause side effects to your fetus and thus should be consumed only after consulting it with the doctor.


Breastfeeding
CONSULT YOUR DOCTOR

Cortan 20mg Tablet passes into the breastmilk in small amounts. Thus, the use of this medicine is not recommended in breastfeeding mothers unless it is prescribed by a doctor.


Driving
CAUTION

It may not be safe to drive while on this medication as you can experience any of the side effects like drowsiness, dizziness, fatigue, or headache, all of which can affect your motor skills and sense of coordination.


Kidney
SAFE IF PRESCRIBED

Cortan 20mg Tablet is safe to use in people suffering from kidney-related issues and therefore no dose adjustment is recommended. But it is advisable that you must inform your doctor if you have any kidney disease, therefore careful dose selection and monitoring of kidney function tests on a regular basis are advised while you are taking this medicine.


Liver
CONSULT YOUR DOCTOR

Cortan 20mg Tablet can affect liver function in people having liver-related ailments and the medicine can interact with existing conditions and aggravate the intensity of it.

Similar Products

Uses of Cortan 20mg Tablet

Allergic reactions/conditions

How does Cortan 20mg Tablet work?

Cortan 20mg Tablet belongs to Glucocorticoids. It works by binding to the receptor and inhibits the release of inflammatory substances thus helping in the treatment of inflammation or allergic disorders.

Side Effects of Cortan 20mg Tablet

Increased hunger, indigestion, agitation, and restlessness are all common adverse effects. Darkening or lightening of skin color, dizziness or lightheadedness, flushing of the face or cheeks, hiccups, increased sweating, and the impression of spinning is less common or rare adverse effects.

Quick Suggestions:
  • Cortan 20mg Tablet helps treat inflammation, severe allergies, flare-ups of ongoing illnesses, and many other medical problems that require either reduction of inflammation or suppression of the immune system.
  • Do not use it more often or for longer than advised by your doctor.
  • Take it with food to avoid an upset stomach.
  • Cortan 20mg Tablet can make it harder for you to fight off infections. Notify your doctor if you have any signs of infection such as a fever or sore throat.
  • Side effects such as mood changes or stomach problems can happen when you start taking Cortan 20mg Tablet. Inform your doctor if this bothers you.
  • Do not stop taking Cortan 20mg Tablet suddenly without talking to your doctor first as it may worsen your symptoms.
Indication
  • Rheumatic Disorders include post-traumatic osteoarthritis, acute gouty arthritis, acute nonspecific tenosynovitis, psoriatic arthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, ankylosing spondylitis, acute and subacute bursitis, and acute nonspecific tenosynovitis.
  • Endocrine disorders include nonsuppurative thyroiditis, primary or secondary adrenocortical insufficiency, congenital adrenal hyperplasia, and hypercalcemia linked to cancer.
  • Pemphigus, bullous dermatitis herpetiformis, severe erythema multiforme, exfoliative dermatitis, mycosis fungoides, and severe psoriasis are examples of dermatological conditions.
  • Seasonal or persistent allergic rhinitis, bronchial asthma, contact dermatitis, atopic dermatitis, serum sickness, and adverse drug reactions are examples of allergic states.
  • Symptomatic sarcoidosis, berylliosis, fulminating, and aspiration pneumonitis are respiratory diseases.
  • Hematologic disorders include acquired (autoimmune) hemolytic anemia, erythroblastopenia, secondary thrombocytopenia, and idiopathic thrombocytopenic purpura (RBC anemia).
  • Edematous States: To cause diuresis or remission of proteinuria in nephrotic syndrome, without uremia, whether it be of the idiopathic type or that caused by lupus erythematosus.
  • Regional enteritis and ulcerative colitis are gastrointestinal disorders.
  • Gastrointestinal Diseases: Ulcerative colitis, regional enteritis.
Pharmacology

Prednisolone is a synthetic adrenocortical drug that functions similarly to glucocorticoids. The Phospholipase A2 enzyme, which produces inflammatory mediators like leukotrienes, SRS-A, and prostaglandins, is inhibited by prednisolone. Prednisolone is quickly and completely absorbed from the GI tract after oral ingestion. Prednisolone has a half-life of 2 to 4 hours before it is excreted and is 70–90% protein-bound in the plasma. The liver is where it is primarily processed, and urine is where it is eliminated.

Dosage & Administration of Cortan 20mg Tablet

Adult-

Allergic Conditions:

  • Day 1: 10 mg PO before breakfast, 5 mg after lunch and after dinner, and 10 mg at bedtime.
  • Day 2: 5 mg PO before breakfast, after lunch, and after dinner, and 10 mg at bedtime.
  • Day 3: 5 mg PO before breakfast, after lunch, after dinner, and at bedtime.
  • Day 4: 5 mg PO before breakfast, after lunch, and at bedtime.
  • Day 5: 5 mg PO before breakfast and at bedtime.
  • Day 6: 5 mg PO before breakfast.

Nephrotic Syndrome:

  • Initial: 2 mg/kg/day (maximum 80 mg/day) in divided doses 3 to 4 times/day until urine is protein-free for 3 consecutive days (maximum: 28 days); followed by 1 to 1.5 mg/kg/dose given every other day for 4 weeks.
  • Maintenance dose: 0.5 to 1 mg/kg/ dose given every other day for 3 to 6 months.

Anti-inflammatory: 

  • 5 to 60 mg per day in divided doses 1 to 4 times/day.

Acute Asthma: 

  • 40-60 mg/day PO in a single daily dose or divided q12 hr for 3-10 days.

Pediatric-

Asthma:

  • 1 year: Acute: 10 mg orally every 12 hours. Maintenance: 10 mg orally every other day.
  • 1 to 4 years: Acute: 20 mg orally every 12 hours. Maintenance: 20 mg orally every other day.
  • 5 to 12 years: Acute: 30 mg orally every 12 hours. Maintenance: 30 mg orally every other day.
  • 12 years: Acute: 40 mg orally every 12 hours. Maintenance: 40 mg orally every other day.

Anti-inflammatory: 

  • 0.05 to 2 mg/kg/day divided 1 to 4 times/day.

Immunosuppression: 

  • 0.05 to 2 mg/kg/day divided 1 to 4 times/day.
Interaction
  • Medicines used to treat tuberculosis (e.g. rifampicin, isoniazid): These medications may reduce the effectiveness of Cortan 20mg Tablet.
  • Blood thinners (e.g. aspirin, warfarin): There is an increased risk of bleeding when taking these medications concurrently with Cortan 20mg Tablet. Close monitoring of blood clotting parameters may be necessary.
  • Antiepilepsy drugs (e.g. carbamazepine, phenobarbital, phenytoin): These medications may reduce the effectiveness of Cortan 20mg Tablet.
  • Anticholinergics (e.g. amitriptyline): Concurrent use with Cortan 20mg Tablet may increase the risk of certain side effects such as increased intraocular pressure and urinary retention.
  • Medicines used for myasthenia gravis (e.g. neostigmine): Cortan 20mg Tablet may interact with these medications, potentially altering their effects.
  • Antidiabetic medications (e.g. insulin): Cortan 20mg Tablet can increase blood sugar levels, which may require adjustments in the dosage of antidiabetic medications.
  • HIV medications (e.g. cobicistat): There may be interactions between Cortan 20mg Tablet and certain HIV medications, so close monitoring is advised.
  • Sex hormones (e.g. estrogen): Concurrent use with Cortan 20mg Tablet may increase the risk of side effects associated with corticosteroid use.
  • NSAIDs (e.g. ibuprofen, naproxen): These medications can increase the risk of gastrointestinal bleeding when taken with Cortan 20mg Tablet.
  • Diuretics (e.g. thiazides, furosemide, ethacrylic acid): Concurrent use with Cortan 20mg Tablet may potentiate the effects of diuretics, leading to electrolyte imbalances.
  • Medicines used to treat lung diseases or asthma (e.g. theophylline, salbutamol, terbutaline, salmeterol, formoterol): These medications may interact with Cortan 20mg TabletG, and careful monitoring of respiratory function may be required.
  • Antibiotic used for fungal infection (e.g. amphotericin B): Cortan 20mg Tablet may increase the risk of side effects associated with amphotericin B.
  • Regarding food interactions, Cortan 20mg Tablet should not be taken with grapefruit or rich protein foods as they may affect the absorption or metabolism of the medication.

It's important to note that this is not an exhaustive list of all possible drug interactions. Always consult with your healthcare provider or pharmacist for a comprehensive understanding of potential interactions before starting Cortan 20mg Tablet or any other medication.

Contraindications

Cortan 20mg Tablet should not be used in the following situations:

Systemic infections: Cortan 20mg Tablet should not be used in the presence of systemic infections unless specific anti-infective therapy is also employed. Corticosteroids can suppress the immune system, making it difficult for the body to fight off infections.

Hypersensitivity: If you have a known hypersensitivity or allergy to any of the ingredients in Cortan 20mg Tablet, it should be avoided.

Ocular herpes simplex: Cortan 20mg Tablet should not be used in individuals with ocular herpes simplex due to the potential risk of corneal perforation. Corticosteroids can exacerbate viral infections such as herpes simplex.

Pregnancy & Lactation

Cortan 20mg Tablet is not recommended for use during pregnancy unless it is considered essential by a doctor. The decision to use this medication during pregnancy should only be made if the expected benefit to the mother outweighs any potential risk to the fetus. Corticosteroids, including Cortan 20mg Tablet, can cross into breast milk and may have the potential to suppress growth, interfere with the production of natural corticosteroids in infants, or cause other unwanted effects.

If you are pregnant or breastfeeding, it is crucial to discuss the potential risks and benefits of using Cortan 20mg Tablet with your healthcare provider. They will be able to evaluate your individual situation and provide guidance on the most appropriate treatment options for you and your baby.

Precautions & Warnings
  • Some anti-inflammatory compounds in ginger can help relax airway membranes, reducing coughing.
  • Staying hydrated by drinking liquids at room temperature can alleviate symptoms such as cough, runny nose, and sneezing.
  • Acid reflux is a common cause of cough. Avoiding foods that can trigger acid reflux can help alleviate the accompanying cough.
  • Stress can affect the immune system and increase the risk of illness. Regular exercise, meditation, deep breathing, and relaxation techniques can help relieve stress and support a healthy immune system.
  • Getting 7-9 hours of sleep each night is important for overall fitness and well-being.
  • Avoiding allergens: If you have known allergies, it is advised to avoid contact with allergens such as pollen, dust, or specific food items that cause allergic reactions.
  • Maintaining personal hygiene and keeping the surroundings clean can help prevent the spread of infections.
  • It is important not to suggest your medicine to someone else and to consult with a doctor before taking any medication, including Cortan 20mg Tablet. Inform your doctor about your medical history, ongoing medications, and any allergies or conditions you may have.
  • Cortan 20mg Tablet should be used with caution in individuals with specific medical conditions such as hypothyroidism, liver disease, kidney failure, seizures, myasthenia gravis, tuberculosis, gastrointestinal disorders, heart disorders, blood disorders, mood swings, psychotic tendencies, adrenal gland disorders, and scleroderma. It can cause side effects such as dizziness, visual problems, and fatigue. Care should be taken while driving or operating machinery.
  • Regular height check-ups by a doctor are recommended for children and teenagers using to detect any growth-related issues early.
  • High or immunosuppressive dosages of corticosteroids may affect the administration of life or live-attenuated vaccinations. Consult with a healthcare professional regarding the use of inactivated viral or bacterial vaccinations.
Storage Conditions

Store in a cool and dry place, protected from light. Keep out of the reach of the children.

Frequently Asked Questions (FAQ)

Cortan 20mg Tablet belongs to a group of medication known as Corticosteroid. It is basically as a reliever of inflammations in the human body and also used to treat skin conditions, asthma and arthritis. This medication works by blocking the specific inflammatory cells that cause swelling, Itching, and pain.

This medicine used for the treatment, prevention, and control of the conditions such as: Allergies Asthma Nephrotic syndrome Lymphoma Sarcoidosis Idiopathic thrombocytopenic purpura Chronic Lymphocytic Leukemia Multiple sclerosis Osteoarthritis Psoriasis Hemolytic anemia Eye discharge Swollen tongue Dermatitis herpetiformis Uveitis Bursitis Rheumatic disorder

Skin thinning Blurred vision Increased risk of infection Decrease urine output Reduction in bone density Weight gain Dizziness Mood changes Stomach upset Increase appetite Behavioural changes Increased glucose level in blood Absence of menstrual periods Acne Mood swings Headache

Yes

It is advisable to take this drug for the duration prescribed by your doctor. Do not stop the treatment suddenly or take for a longer period than recommended by your doctor.

No

Yes

Certain antibiotics may increase the metabolism of this medication and hence decrease its effects.

Cortan 20mg Tablet should be used with caution in children and adolescents (below 18 years). Long term usage should be avoided. Your doctor will decide the dose, frequency and duration depending on the child’s age, body weight and disease conditions.

Depending upon the severity of your medical condition, your doctor may prescribe it to you daily for a specific duration. However, do not take it endlessly on your own without a doctor's advice.

The effect of the medication stays for 12-14 hours in most cases but can differ from person to person and you must consult a doctor to understand your dosage pattern as it depends on the disease for which you are consuming the tablet.
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ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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