Salost DR 35mg 4pcs Tablet

✔️ Salost DR belongs to the bisphosphonate group of medicines that slow bone loss, increase bone mass, and reduce the risk of fractures. It is prescribed for:

1. Postmenopausal Osteoporosis: Prevention and treatment in women after menopause.
2. Osteoporosis in Men: Increasing bone mass in men with osteoporosis.
3. Steroid-Induced Osteoporosis: Prevention and treatment in men and women on long-term corticosteroid therapy.
4. Paget’s Disease: Treatment of abnormal bone metabolism in men and women.

✔️ Dosage

1. Postmenopausal Osteoporosis:
   • 5 mg daily, 35 mg weekly, or 150 mg monthly.
2. Prevention of Postmenopausal Osteoporosis:
   • 5 mg daily.
3. Steroid-Induced Osteoporosis:
   • 5 mg daily for individuals on prednisone (≥7.5 mg/day).
4. Osteoporosis in Men:
   • 35 mg weekly on the same day each week.

✔️ Administration

• Take Salost DR with a full glass (120 mL) of plain water while upright (sitting or standing).
• Avoid lying down for at least 30 minutes after taking the tablet to reduce the risk of esophageal irritation.
• Do not eat, drink (other than water), or take other medications for at least 30 minutes after the dose.
• Missed Dose Instructions:
  • 35 mg Weekly Dose: Take the missed dose the morning after it is remembered and return to the regular schedule. Avoid taking two doses on the same day.
  • 150 mg Monthly Dose: If the next dose is more than 7 days away, take the missed dose as soon as possible, and resume the normal schedule.

1. Pediatric Use: Not established; not recommended for children.
2. Elderly: No dosage adjustments necessary; safe and effective in individuals ≥75 years.
3. Renal Impairment: Avoid severe renal impairment (creatinine clearance <30 mL/min).

✔️ Side Effects

• Chest pain, difficulty swallowing, or severe heartburn.
• Severe joint, muscle, or bone pain.
• Jaw pain, swelling, or numbness.
• Mild stomach upset, diarrhea, constipation, or gas.
• Mild joint or back pain.
• Headache.

✔️ Overdose Effects

• Symptoms: Hypocalcemia, nausea, or other electrolyte imbalances.
• Treatment: Administer calcium or magnesium antacids to bind and reduce absorption. Consider gastric lavage if a significant overdose occurs.

✔️ Interactions

• NSAIDs/Aspirin: May increase gastrointestinal irritation.
• Antacids, Calcium, Magnesium, or Aluminum Supplements: Can interfere with the absorption of Risedronate. Avoid taking them within 30 minutes of Salost DR.

✔️ Contraindications

• Hypersensitivity to Risedronate.
• Severe renal impairment (creatinine clearance <30 mL/min).
• Hypocalcemia (low blood calcium).
• Pregnancy and lactation.

✔️ Pregnancy & Lactation

• Pregnancy: Not recommended (Category C). Discontinue immediately if taken during pregnancy.
• Lactation: Not to be used; unknown if Risedronate is excreted in breast milk.

✔️ Precautions & Warnings

• Ensure adequate calcium and vitamin D intake if dietary levels are insufficient.
• Do not take it if you cannot remain upright for 30 minutes.
• Use caution in individuals with poor kidney function or esophageal disorders.
• Immediately stop the medication and seek medical attention if symptoms of an allergic reaction occur (e.g., swelling of the face or difficulty breathing).

✔️ Storage Conditions

• Store in a cool, dry place, protected from light and moisture.
• Keep out of reach of children.