Diosmin and Hesperidin are flavonoid compounds that function as venotonic and vasoprotective agents. They improve venous circulation by enhancing venous tone through the prolongation of norepinephrine activity on the vein walls. This action helps reduce venous capacity, venous distensibility, and venous emptying time.
The combination also protects the microcirculation by reducing inflammation within the veins. It inhibits leukocyte activation and decreases the release of inflammatory mediators such as prostaglandins and free radicals, thereby improving capillary integrity and reducing capillary permeability.
Additionally, Diosmin and Hesperidin support lymphatic function by increasing lymphatic flow and enhancing lymphatic drainage, which helps minimize fluid accumulation and tissue swelling.
Sangril should not be used in individuals who:
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Diosmin+hesperidin is used in the treatment of Varicose veins (twisted and enlarged veins), lymphedema (swelling of arms and legs), and acute and chronic haemorrhoids (swollen veins of the lower rectum and anus). The detailed uses of Diosmin+hesperidin are as follows:
• Varicose Veins: Diosmin+hesperidin improves vein tone and reduces swelling and discomfort.
• Hemorrhoids (Piles): Diosmin+hesperidin treats both acute and chronic cases by reducing inflammation.
• Lymphedema: Diosmin+hesperidin eases swelling in arms and legs due to lymphatic blockage.
• Venous Leg Ulcers: Diosmin+hesperidin promotes healing when combined with compression therapy.
For optimal absorption and gastrointestinal tolerance, Sangril tablets should be taken during meals.
Consuming alcohol along with Diosmin+hesperidin is not advisable as it may cause unpleasant side effects or you may become more sensitive to the effects of alcohol.
There are no adequate and well-controlled studies on pregnant women.
There is no substantial research yet on the use of Diosmin+hesperidin in breastfeeding/nursing mothers. Please consult a doctor.
Caution should be exercised when driving or operating machinery, as Diosmin+hesperidin may cause dizziness.
Limited information is available for the use of Diosmin+hesperidin in patients suffering from kidney impairment. Please consult your doctor if you have any concerns.
Limited information is available for the use of Diosmin+hesperidin in patients suffering from liver impairment. Please consult your doctor if you have any concerns.
Acute Hemorrhoidal Attack
Chronic Hemorrhoids
Chronic Venous Insufficiency
Acute Hemorrhoids
Chronic or Recurrent Internal Hemorrhoids
Chronic Venous Insufficiency
Leg Ulcers
Always follow the dosage prescribed by your healthcare provider.
Animal studies have shown no evidence of teratogenic effects. Clinical experience in humans has not demonstrated harmful effects during pregnancy. However, treatment should be used only when clearly indicated and under medical supervision.
Because there is insufficient information regarding the excretion of Diosmin and Hesperidin into breast milk, breastfeeding is generally not recommended during treatment.
Store below 30°C in a dry place, protected from light and moisture. Keep out of the sight and reach of children.
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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.