Prevenar 13 Injection

✔️ Uses of Prevenar 13 Injection

Pneumococcal infections (infections of the ear, blood, brain, and lungs)

✔️ How does Prevenar 13 Injection work?

The Pneumococcal Polysaccharide Vaccine stimulates the immune system by causing a mild infection, which leads to the production of antibodies to protect against future infections.

✔️ Side Effects of Prevenar 13 Injection

• Tenderness and redness at the injection site
• Irritability
• Decreased appetite
• Increased sleep
• Muscle pain
• Fever

✔️ Quick Suggestions:

• Pneumococcal Polysaccharide Vaccine is given to prevent invasive diseases caused by pneumococcal bacteria such as pneumonia, meningitis, ear, and blood infections.
• It is usually given as an injection into the muscle (intramuscular) of the upper arm.
• Only one dose is needed for most people. A booster dose can be given 5 years after the first dose.
• Inform your doctor if you have an infection with a high temperature, as vaccination may need to be delayed until recovery.
• It may cause fever. Inform your doctor if it does not go away or if it gets higher than 102 degrees Fahrenheit.

✔️ Indication of Prevenar 13 Injection

Vaccination helps prevent invasive diseases, pneumonia, and otitis media caused by Streptococcus pneumoniae in infants, children, and youths from 6 weeks to 17 years old. It also prevents invasive diseases and pneumonia in adults aged 18 years and above, including the elderly. The decision to use vaccines should be based on official recommendations, considering the risk of invasive infection and pneumonia in different age groups and geographical areas, as well as underlying health conditions and serotype variations.

✔️ Pharmacology

These products convey active immunity via stimulation of the production of endogenously produced antibodies.

✔️ Dosage & Administration of Prevenar 13 Injection

The Pneumococcal Polysaccharide Vaccine is administered in a series of doses based on age:

Infants from 6 weeks to 6 months of age:

• Three-dose primary series: Three doses, with the first dose usually given at 2 months of age and an interval of at least 1 month between doses. The first dose can be given as early as six weeks of age. A booster dose is recommended at least 6 months after the last priming dose.
• Two-dose primary series: Alternatively, a series of three doses may be given as part of routine infant immunization. The first dose can be administered at 2 months of age, with a second dose 2 months later. A booster dose is recommended at least 6 months after the last primary dose.

Previously unvaccinated older infants and children:

• Infants aged 7-11 months: Two doses with an interval of at least 1 month between doses. A third dose is recommended in the second year of life with an interval of at least 2 months between doses.
• Children aged 12-23 months: Two doses with an interval of at least 2 months between doses. The need for a booster dose after this schedule has not been established.

Prevenar 13 Injection/Vaccine is administered by a doctor or nurse as an intramuscular injection in the anterolateral aspect of the thigh in infants or the deltoid muscle in children and adults. It should not be injected in the gluteal area or areas with major nerve trunks and blood vessels. The correct dose and duration will be determined by your doctor based on your age, body weight, and health condition.

✔️ Interaction

Prevenar 13 Vaccine 0.5 ml may interact with certain drugs and diseases:

Drug-Drug Interactions:

• Immunosuppressants (sirolimus, tacrolimus, hydrocortisone), betamethasone, azathioprine, etanercept, and leflunomide: Concomitant use with Prevenar 13 may interfere with the immune response.
• Medicines to reduce fever: These medicines may reduce the body's immune response to the vaccine.
• Prior immunization with PPSV23: Previous vaccination with PPSV23 can affect the immune response to Prevenar 13.
• Prevenar 13 should not be mixed with other vaccines in the same syringe. If administered with another vaccine, a separate syringe and different injection site must be used.

Drug-Disease Interactions:

• Prevenar 13 Vaccines should not be used in patients with severe infections and high fever.

✔️ Contraindications

• History of a serious allergic reaction such as anaphylaxis to any of the contents of Prevenar 13 vaccine
• History of allergy to any vaccine that contained diphtheria toxoid

✔️ Pregnancy & Lactation

Pregnancy Category C. Creature generation thinks have appeared an antagonistic impact on the embryo and there are no satisfactory and well-controlled things about in people, but potential benefits may warrant utilize of the medicate in pregnant ladies in spite of potential dangers

✔️ Precautions & Warnings

Before using Prevenar 13 Vaccine 0.5 ml, inform your doctor if you:

• Are allergic to any of its components.
• Have a severe infection with high fever, bleeding problems, weak immune system, or seizures.
• Experience fever after vaccination; if it persists or crosses 102°F, talk to your doctor.
• Are pregnant or a nursing mother; consult a doctor before use.
• Have extreme renal, hepatic, cardiac, vascular, or pneumonic issues.
• Are on immunosuppressants; your ability to achieve required antibody titers may be affected.
• Have multiple myeloma, Hodgkin's or non-Hodgkin's lymphoma, or chronic alcoholism, as vaccine effectiveness may be reduced.
• The vaccination should be given 2 weeks before starting immunosuppressive treatment or at least 3 months after treatment completion.

✔️ Storage Conditions

Store the injection in the refrigerator at 2°C to 8°C (36°F to 46°F), protecting it from light. Do not freeze the vaccine, and discard it if it has been frozen. The vaccine can be stable at temperatures up to 25°C (77°F) for 4 days, but such conditions are not recommended for storage or transportation. Remember to discard the vaccine after the expiry date.