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Scabo 12 is prescribed for the treatment of various parasitic infections, including:
- Strongyloidiasis (intestinal infections by Strongyloides stercoralis)
- Onchocerciasis (Onchocerca volvulus infections)
- Filariasis
- Scabies
- Pediculosis capitis (head lice)
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✅ Description:
Ivermectin acts by binding with high affinity to glutamate-gated chloride channels present in invertebrate nerve and muscle cells. This interaction increases the influx of chloride ions, resulting in hyperpolarization, paralysis, and death of the parasite.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Common Side Effects:
Mild burning, stinging, or tingling at the application site
These are typically mild and temporary.
✔️ Precautions:
- Inform your doctor if you have existing skin conditions, asthma, or known allergies to medicines, foods, or topical products.
- Consult a healthcare provider before using this product if you are pregnant or breastfeeding, even though it is generally considered safe.
✔️ Uses
- Parasitic infections
✔️ Dosage & Administration
For Strongyloidiasis:
Single oral dose of 200 mcg/kg of body weight.
Stool exams may be repeated to confirm eradication.
| Body Weight (kg) | Ivermectin Dose |
|---|---|
| 15–24 | 3 mg |
| 25–35 | 6 mg |
| 36–50 | 9 mg |
| 51–65 | 12 mg |
| 66–79 | 15 mg |
| >80 | 200 mcg/kg |
For Onchocerciasis:
Single oral dose of 150 mcg/kg.
Re-dosing may be required every 3–12 months based on clinical response.
| Body Weight (kg) | Ivermectin Dose |
|---|---|
| 15–25 | 3 mg |
| 26–44 | 6 mg |
| 45–64 | 9 mg |
| 65–84 | 12 mg |
| >85 | 150 mcg/kg |
COVID-19 Off-label Use (not a standard indication):
Treatment: Ivermectin 6 mg × 2 tablets daily for 5 days.
Prophylaxis: Same dose on Day 1 and Day 7 based on weight.
- Children <15 kg: Safety and efficacy not established.
- Elderly (65+): Limited data; no specific adjustments unless clinically indicated.
✔️ Administration
- Take the tablet whole with water on an empty stomach.
- Avoid caffeine and drink plenty of fluids for optimal absorption.
- Always follow your physician’s instructions regarding dosage and treatment duration.
✔️ Drug Interactions
Warfarin: Rare cases of elevated INR reported; monitor coagulation parameters if co-administered.
✔️ Contraindications
Known hypersensitivity to Ivermectin or any component of the formulation.
✔️ Side Effects
Common:
- Application site burning (when applied topically)
Systemic (Oral):
Strongyloidiasis:
- Dizziness, somnolence
- GI upset: nausea, diarrhea, abdominal pain
- Rash, pruritus
- Fatigue
- Onchocerciasis:
- Pruritus, rash, joint pain
- Lymph node swelling/tenderness
- Eye symptoms (rarely severe): uveitis, conjunctivitis
- Fever, hypotension, asthma worsening (rare)
- Severe skin reactions (e.g., Stevens-Johnson Syndrome – rare)
✔️ Warnings
- Mazzotti Reaction: In patients with onchocerciasis, allergic/inflammatory reactions may occur due to parasite death, including fever, rash, hypotension, and lymphadenopathy.
- Loa loa co-infection: Risk of severe or fatal encephalopathy in heavily infected individuals.
- Avoid use in pregnancy unless necessary. Not enough studies are available to ensure safety.
- Lactation: Excreted in low levels in breast milk; use only if benefits outweigh risks.
✔️ Storage
- Store in a cool, dry place below 30°C.
- Protect from light and keep out of children’s reach.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
