Napro-A Plus 500 Tablet | Pain Relief | ePharma
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Napro-A Plus 500 Tablet 10Pcs

Generic: Esomeprazole + Naproxen

Type: Tablet

Pack Size: 10 Pcs

  • Napro-A Plus 500 (Naproxen Sodium 500mg + Esomeprazole 20mg)Tablet is a painkiller and belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) used to reduce and relieve pain. Pain is an unpleasant physical sensation caused by illness or injury. Napro-A Plus 500 Tablet combines Naproxen and esomeprazole. Naproxen is an anti-inflammatory drug that reduces pain and inflammation by blocking the action of the body's cyclo-oxygenase (COX) enzyme to produce certain chemical substances (prostaglandins) that cause pain and swelling. However, Naproxen can cause gastric discomfort, acidity, and risk of stomach ulcers. Therefore, Napro-A Plus 500 Tablet, when combined with esomeprazole (proton pump inhibitors), reduces the amount of acid made by the stomach, thus preventing damage to the stomach. The combination helps alleviate pain with minimal gastric irritation caused due to Naproxen alone.
  • It is essential to take Napro-A Plus 500 Tablets as prescribed by the doctor. You should take Napro-A Plus 500 Tablet for as long as your doctor has prescribed it for you based on your medical condition. Possible side effects of Napro-A Plus 500 Tablet are indigestion, stomach pain, constipation, dizziness, nausea, and diarrhea. These side effects do not require medical attention and usually go away over time. If the side effects persist or worsen, please consult your doctor.
  • Before taking Napro-A Plus 500 Tablet, inform your doctor if you have any known allergy to Naproxen, esomeprazole, other NSAIDs, or other medications. If pregnant or breastfeeding, please inform your doctor before taking the Napro-A Plus 500 Tablet. Also, inform the doctor if you have a history of heart rhythm problems or ulcers due to painkillers. Patients with age above 65 years, with pre-existing cardiac diseases such as heart failure, hypertension or stroke, gastrointestinal bleeding (due to pain killers), gastric ulcers, respiratory diseases such as asthma, liver diseases, kidney diseases, or bleeding disorders should use Napro-A Plus 500 Tablet only when prescribed by a doctor. It is important to keep your doctor informed about your health condition and all the medicines you take before taking Napro-A Plus 500 Tablet to avoid any possible side effects.

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✅ Description:

Napro-A Plus 500 Tablet is a combination medicine (Esomeprazole + Naproxen) that helps in relieving pain. It is used to relieve pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Safety Advices


Alcohol

You are recommended to avoid alcohol consumption with Napro-A Plus 500 Tablet as it may increase the risk of stomach bleeding and ulcer.


Pregnancy

There is limited data on how Napro-A Plus 500 Tablet affects pregnancy. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Napro-A Plus 500 Tablet.


Breastfeeding

Napro-A Plus 500 Tablet passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake of Napro-A Plus 500 Tablet. Your doctor will weigh the benefits and any potential risks before prescribing Napro-A Plus 500 Tablet to you.


Driving

Napro-A Plus 500 Tablet may cause dizziness, tiredness, drowsiness, or vision problems in some people. So, drive only if you are alert after taking Napro-A Plus 500 Tablet.


Kidney

Napro-A Plus 500 Tablet is not recommended for use in patients with moderate to severe and severe renal impairment. The dose may be adjusted by your doctor as required. So, it should be used only when prescribed by your doctor.


Liver

Napro-A Plus 500 Tablet is to be used with caution in people having liver diseases. Dose adjustments may be necessary. So, you should use it only with your doctor's prescription.

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✔️ Uses of Napro-A Plus 500 Tablet
  • Pain Relief
✔️ How Napro-A Plus 500 Tablet works?

Napro-A Plus 500 Tablet blocks the release of a substance called prostaglandin in the body. Prostaglandins are responsible for the signs of inflammation such as pain and fever. This anti-inflammatory action is useful in the reduction of pain, stiffness, swelling, and fever connected with inflammation.

✔️ Side effects of Napro-A Plus 500 Tablet
  • Confusion
  • Headaches
  • Ringing in the ears
  • Changes in vision
  • Tiredness and feeling sleepy
  • Dizziness
  • Rashes
  • Fits or seizures
  • Bruising, itching, sweating, skin being more sensitive to the sun, or hair loss
  • Changes in eyesight (eye pain)
  • Hearing loss and ringing in the ears
  • Fluttering feeling in heart
  • Thirst, fever, feeling tired or generally unwell
  • Swelling of your hands, feet, or legs
  • Difficulty breathing, including shortness of breath, wheezing, or coughing
✔️ Quick Suggestions:
  • Napro-A Plus 500 Tablet is used to treat various painful conditions.
  • Take it with a glass of milk in order to prevent side effects such as indigestion.
  • If you have asthma, symptoms such as wheezing or breathlessness might get worse Napro-A Plus 500 Tablet. In such a case see your doctor right away.
  • Regular physical activity, such as walking or swimming, can strengthen muscles and alleviate joint stiffness.
  • Engaging in yoga can improve joint flexibility and pain management. It's essential to maintain a healthy weight through regular low-impact exercise and a balanced diet.
  • Adequate sleep is crucial to reduce inflammation and swelling.
  • Applying a hot or cold compress to the joints can be helpful, along with acupuncture, massage, and physical therapy.
  • Foods rich in flavonoids, such as soy, berries, broccoli, grapes, and green tea, can help reduce inflammation.
  • A diet high in antioxidants, calcium, and vitamin B12, such as berries, cherries, leafy green veggies, and black peppers, can help counteract the long-term effects of medication. Avoid smoking and drinking alcohol
  • Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics that can help prevent excess stomach acid production.
  • Avoid consuming foods or drinks that can trigger acid reflux or heartburn, such as onions, peppermint, chocolate, citrus fruits or juices, tomatoes, high-fat, and spicy foods.
  • Inform your doctor if you have or ever had ulcers in your stomach or intestines.
  • Inform your doctor if you are planning to have an operation (even a minor one, such as tooth extraction) since Napro-A Plus 500 Tablet increases the risk of bleeding.
✔️ Indication of Napro-A Plus 500 Tablet

It is used to relieve pain in the following conditions:

  • Muscles, joints, and tendons problems such as strains, gout, ankylosing spondylitis (pain and stiffness in the neck and back), or arthritis
  • Painful heavy periods and bleeding due to insertion of an intrauterine device (women)
  • Migraine headache
  • Rheumatoid arthritis (children)
✔️ Pharmacology

The pill consists of two parts: a quick-release coating of Esomeprazole Magnesium and an enteric-coated Naproxen core. This design allows for the release of Esomeprazole into the stomach first, followed by the release of Naproxen in the small intestine.

Naproxen is a type of nonsteroidal anti-inflammatory drug (NSAID) that has both pain-relieving and fever-reducing properties. It functions by inhibiting the production of prostaglandins. Esomeprazole, on the other hand, is a proton pump inhibitor that suppresses the secretion of gastric acid by blocking the H+/k+ -ATPase in the parietal cell of the stomach. By acting specifically on the proton pump, Esomeprazole decreases gastric acidity by inhibiting the final stage of acid production.

✔️ Dosage & Administration of Napro-A Plus 500 Tablet
  • Before using this tablet, it is important to carefully consider the potential benefits and risks and to explore other treatment options. It is recommended to use the lowest effective dose for the shortest duration, consistent with individual patient treatment goals. If a lower dose of esomeprazole than the total daily dose of 40 mg is appropriate, then a different treatment option should be considered.
  • For adults with Rheumatoid Arthritis, Osteoarthritis, and Ankylosing Spondylitis, the recommended dose is one tablet twice daily of either 375 mg naproxen/20 mg of esomeprazole or 500 mg naproxen/20 mg of esomeprazole.
  • For adolescent patients aged 12 years and older with Juvenile Idiopathic Arthritis and a weight greater than 50 kg, the recommended dose is one tablet twice daily of either 375 mg naproxen/20 mg of esomeprazole or 500 mg naproxen/20 mg of esomeprazole.
  • For adolescent patients aged 12 years and older with Juvenile Idiopathic Arthritis and a weight between 38 kg to less than 50 kg, the recommended dose is one tablet twice daily of 375 mg naproxen/20 mg of esomeprazole.

Take Napro-A Plus 500 Tablet as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

✔️ Interaction

Napro-A Plus 500 Tablet may interact with several medications, including anti-inflammatory drugs, blood thinners, steroids, diuretics, heart and blood pressure medications, antidepressants, and rheumatoid arthritis drugs. It may also interact with alcohol, increasing the risk of stomach bleeding, drowsiness, and dizziness. Individuals with diabetes, stomach ulcer, gastrointestinal bleeding, asthma, kidney, liver, or heart problems, and autoimmune conditions like systemic lupus erythematosus, colitis, or Crohn's disease should consult a doctor before taking Napro-A Plus 500 Tablet. It is important to inform your healthcare provider of all the medications, supplements, and medical conditions before taking Napro-A Plus 500 Tablet to prevent any potential interactions or adverse effects.

✔️ Contraindications

The use of Napro-A Plus 500 Tablet is contraindicated in individuals who have a hypersensitivity to any of the tablet's ingredients or substituted benzimidazoles. Napro-A Plus 500 Tablet should not be taken if an individual has a history of asthma, urticaria, or other allergic responses after taking aspirin or other NSAIDs.

Furthermore, the use of Napro-A Plus 500 Tablet during the peri-operative period of coronary artery bypass graft (CABG) surgery is not recommended. This is because it can increase the risk of bleeding and other complications during and after the surgery.

✔️ Pregnancy & Lactation

Category C pregnancy. It should be avoided in late pregnancy since it may cause premature closure of the ductus arteriosus. Because of the Naproxen component, this tablet should not be taken by nursing mothers.

✔️ Precautions & Warnings
  • It is important to follow the doctor's instructions and use Napro-A Plus 500 Tablet only as directed, taking into account any potential risks and benefits.
  • Patients should not exceed the recommended dose or duration of treatment. If any unusual symptoms or side effects occur, such as stomach pain, bloody stools, chest pain, shortness of breath, or signs of an allergic reaction (such as rash, itching, or swelling), the patient should seek medical attention immediately.
  • Individuals at risk of osteoporosis-related fractures should consume enough calcium and vitamin D.
  • Esomeprazole in Napro-A Plus 500 Tablet may interfere with some laboratory tests (such as a urine test for tetrahydrocannabinol-THC and a blood test to detect certain tumors), potentially resulting in incorrect test results. Assure that all laboratory employees and your doctors are aware that you are taking Napro-A Plus 500 Tablets.
  • Vitamin B-12 deficiency has been pursued by regular monitoring and, on rare occasions, esomeprazole in Napro-A Plus 500 Tablet. If people use Napro-A Plus 500 Tablet on a regular basis, the danger increases.
  • It is also important to inform the doctor about any other medications, supplements, or medical conditions before starting treatment with Napro-A Plus 500 Tablet to avoid potential interactions and complications.
✔️ Storage Conditions

Protect from light and moisture by storing at a temperature below 30°C. Keep out of children's reach.

Frequently Asked Questions (FAQ)

Although Napro-A Plus 500 Tablet can cause an increase in blood pressure, this is not a common side effect. If you are a hypertensive (patient with high blood pressure) and have been prescribed Napro-A Plus 500 Tablet, always visit your doctor if you suffer high blood pressure while taking the medication.

If you miss a dose of Napro-A Plus 500 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not take double the dose.

Napro-A Plus 500 Tablet contains naproxen, which is a Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). It can lessen pain, swelling, redness and heat (inflammation) in many painful conditions. Moreover, your doctor will decide the dose depending upon your age, body weight and disease condition.

It is important to note that Napro-A Plus 500 Tablet should not be used during the third trimester of pregnancy as it may cause harm to the developing baby. It is also not recommended for use while breastfeeding as it may pass into breast milk and harm the infant. If you are pregnant or planning to become pregnant, or if you are breastfeeding, you should always consult with your doctor before taking any medication, including Napro-A Plus 500 Tablet. Your doctor will weigh the benefits and risks of the medication and help you make an informed decision.

Napro-A Plus 500 Tablet does not cure arthritis but relieves symptoms of arthritis-like joint pain, swelling and stiffness. Arthritis is a chronic condition of joints with pain and inflammation.

Napro-A Plus 500 Tablet may show its action within one hour

Napro-A Plus 500 Tabletmay remain effective in the body for approximately 8-12 hours.

Napro-A Plus 500 Tablet can be taken along with food or after food but make sure that you drink enough water (staying hydrated well), when you are taking this medicine. This is especially important when you have kidney problems. However, consult your doctor before taking this medicine.
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ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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