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Naproxen 10% Gel is used to treat Rheumatoid arthritis, Osteoarthritis, Ankylosing spondylitis, Mild to moderate pain, Tendonitis, Acute musculoskeletal disorders, Bursitis
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✅ Description:
Diproxen is a non-steroidal anti-inflammatory drug (NSAID) formulated for topical use to relieve musculoskeletal pain, including soft tissue injuries, sprains, and strains. It also alleviates localized inflammation and discomfort related to bone and joint conditions. The gel is applied externally and is not intended for systemic use.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Mechanism of Action
Naproxen reversibly inhibits cyclooxygenase enzymes COX-1 and COX-2, reducing the formation of prostaglandin precursors. This action produces anti-inflammatory, analgesic, and antipyretic effects. Additionally, it can inhibit platelet aggregation.
✔️ Side Effects
Generally well-tolerated with no frequent side effects when used as directed
✔️ Indications
- Relief from localized pain due to strains, sprains, or soft tissue injuries
- Management of inflammation in musculoskeletal conditions
- Pain associated with bone and joint disorders
✔️ Dosage & Administration
For external use only
- Apply a thin layer to the affected area as directed by your physician
- Massage gently into clean, dry skin
- Wash hands thoroughly after application, unless treating the hands
- Avoid contact with the eyes, nose, mouth, or broken skin
✔️ Drug Interactions
- Methotrexate: May enhance toxicity
- Aspirin, Warfarin: Increased risk of GI bleeding
- ACE inhibitors/ARBs: May reduce the antihypertensive effect
- Diuretics: Decreased natriuretic response
- Lithium: May raise serum levels and reduce clearance
- Antacids, Sucralfate, Colestyramine: May delay naproxen absorption
- β-blockers (e.g., propranolol): May reduce antihypertensive efficacy
- Probenecid: May increase naproxen levels
✔️ Precautions & Warnings
Use with caution in patients with:
- Cardiovascular conditions (e.g., hypertension, fluid retention, CHF)
- History of GI disorders (bleeding, ulcers)
- Liver or kidney impairment
- Asthma or hypersensitivity to NSAIDs
- Elderly patients
- During lactation
- Avoid application on broken, infected, inflamed, or diseased skin.
✔️ Storage:
Keep below 30°C temperature, protected from light & moisture. Keep out of the reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
