Actidex 25mg Tablet 10Pcs

Actidex is used for the treatment of moderate to severe pain. It helps in relieving pain, such as dental pain, muscle pain, joint pain, and pain during menstruation. Actidex should be taken with food, preferably with an adequate amount of water. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it. The most common side effects of this medicine include nausea, vomiting, stomach pain, diarrhea, and indigestion. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.

Uses of Actidex

• Pain relief

Side effects of Actidex

Common

• Vomiting
• Nausea
• Stomach pain
• Indigestion
• Heartburn

How to use Actidex

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Actidex is to be taken empty stomach.

How Actidex works

Actidex is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

Quick Tips

• You have been prescribed Actidex to relieve pain and inflammation.
• Take it with food or milk to prevent upset stomach.
• Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
• Do not take indigestion remedies (antacids) within two hours of taking Actidex.
• Avoid consuming alcohol while taking Actidex as it can increase your risk of stomach problems.
• Inform your doctor if you have a history of heart disease or stroke.
• Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.

Brief Description

Indication

Pain, Dysmenorrhea, Rheumatic disorders

Administration

Should be taken on an empty stomach. Take 30 min before meals, esp for quick relief of acute pain.

Adult Dose

Adult: PO Rheumatic disorders 100-200 mg/day in 2-4 divided doses. Max: 300 mg/day in divided doses. Pain and inflammation 25-50 mg 6-8 hrly. Max: 300 mg/day. Elderly: Initial total daily dose should not exceed 50 mg/day. May increase to the doses recommended for general population only if well tolerated. Hepatic Impairment: Mild to moderate impairment: Reduce initial dose to 50 mg/day. Not to be used in severe hepatic impairment.

Renal Dose

Mild renal impairment: Reduce initial dose to 50 mg/day. Not to be used in moderate to severe renal impairment.

Contraindication

Dexketoprofen tablets are not recommended to use in patients who are: - Allergic to this product or any of its components, aspirin or other non-steroidal anti-inflammatory medicines. - Have suffered attacks of asthma, bronchospasm, acute rhinitis, nasal polyps, urticaria, angioedema (swollen face, eyes, lips, or tongue, or difficulty in breathing), after taking aspirin or other non-steroidal anti-inflammatory medicines. - Have or have previously suffered from a peptic ulcer or chronic gastro-intestinal disorders. - Have had previously gastro-intestinal haemorrhage (bleeding). - Have suffered from bronchial asthma. - Have severe heart failure, moderate to severe renal dysfunction or severely impaired hepatic function. - Have a bleeding disorder, a blood clotting disorder or taking an anticoagulant. - Pregnant or breast-feeding.

Mode of Action

Dexketoprofen exhibits anti-inflammatory, analgesic and antipyretic properties. It potently inhibits the enzyme cyclooxygenase resulting in prostaglandin synthesis inhibition.

Precaution

The medicine should be used with caution in conditions mentioned below: - Allergic to any other medicines. - Kidney disease, liver disease, heart disease or fluid retention conditions. - Blood disorder, systemic lupus erythematosus or mixed connective tissue disease.

Side Effect

As with all medicines, Dexketoprofen may cause some unwanted effects in some patients. These are described below and are characteristic of non steroidal anti-inflammatory drugs: - Common (1 - 10%): nausea, vomiting, diarrhoea, stomach pain or heartburn. - Uncommon (0.1 - 1%): sleep disorders, nervousness, headache, dizziness,vertigo, palpitations, constipation, dry mouth, flatulence, skin rash, fatigue, hot flushes, shivering, general malaise. - Rare (0.01-0.1%): stomach ulceration, gastric haemorrhage or perforation, pins and needles, high blood pressure, water retention, slowed breathing rate, increased hepatic enzymes, increased sweating. - Very rare / isolated cases (<0.01%): blurred vision, ringing in the ear, low blood pressure, haematological reactions, hepatic or renal damage, dermatological and photosensitivity reactions, bronchospasm or anaphylaxis. - In patients with systemic lupus erythematosus or mixed connective tissue disease, anti-inflammatory medicines may rarely cause isolated cases of fever, headache and rigidity of the nape (back of the neck).

Interaction

Increased risk of GI ulcers & bleeding (synergistic effect) w/ other NSAIDs. Increased risk of haemorrhagic effect of oral anticoagulants. Increased risk of haemorrhage w/ heparin. Increased blood lithium levels, which may reach toxic values, w/ lithium. Increased haematological toxicity of methotrexate at high dose of ?15 mg/wk. Increased toxic effects of hydantoins & sulphonamides. Increase risk of bleeding & damage of GI mucosal w/ anticoagulant. Increase hypoglycemic effect of sulfonylurea agents.