Phenadryl Syrup 100ml

Phenadryl syrup is indicated for the treatment of allergic diseases such as hay fever, allergic rhinitis, urticaria, angioedema, atopic dermatitis, contact dermatitis, gastrointestinal allergy, pruritus, physical allergies, reaction to injection of contrast media, reaction to therapeutic preparation, and allergic transfusion reactions; also postoperative nausea and vomiting and motion sickness. It is also used for the treatment of certain forms of parkinsonism and certain allergic conjunctivitis. Sometimes it may be used as a nighttime sleep aid and for the short-term management of insomnia.

Antihistamine and antitussive:
Tablet:

• Adults: 25 mg to 50 mg 3 to 4 times daily.
• Children (10 years or over): 25 mg 3 or 4 times daily or as directed by the physician.

Syrup:

• Children under 2 years: 2.5 mL every 4 to 6 hours.
• Children 2 to under 6 years: 5 mL every 4 to 6 hours.
• Children 6 to 12 years: 10-20 mL every 4 to 6 hours.
• Adults and children≥12 years: 10-20 mL every 4 to 6 hours.

Antidepressants, particularly of the tricyclic and monoamine oxidase inhibitor types, may interact with diphenhydramine. MAO inhibitors prolong and intensify the anticholinergic effects of antihistamines. The CNS effect is increased by alcohol and other CNS depressant drugs.

Diphenhydramine is contraindicated for premature or newborn infants. Hypersensitivity to any of the components of this drug. Asthma attack, narrow-angle glaucoma, prostatic hypertrophy, stenosing peptic ulcer, pyloroduodenal obstructions, bladder neck obstruction, patients receiving antidepressant therapy.

Side effects include drowsiness, dizziness and dryness of mouth, nausea and vomiting. Other infrequently reported effects are vertigo, palpitation, blurring of vision, headache, restlessness, insomnia and thickening of bronchial secretions. Allergic reactions, diarrhoea, vomiting and excitation may also occur.

Safety for use in pregnancy and lactation has not been established. Its use therefore in such patients should involve consideration of expected benefits and possible risks.

Patients should be cautioned not to operate vehicles or hazardous machinery until their response to the drug has been determined.

Do not store above 30°C. Keep away from light and wet places. Keep out of reach of children.