Vildapin 50 | Uses, Dosage, Price, Interaction
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Vildapin 50, 1 Strip

Generic: Vildagliptin

Type: Tablet

Pack Size: 10 Pcs

Vildagliptin is a DPP-4 (Dipeptidyl Peptidase-4) inhibitor that helps regulate blood sugar by preventing the breakdown of incretin hormones. Incretins such as GLP-1 and GIP are produced in the intestine and increase after eating. These hormones stimulate insulin release from pancreatic β-cells and reduce glucagon secretion from α-cells when blood glucose levels are normal or high. They are normally degraded quickly by DPP-4.

By blocking DPP-4, Vildagliptin increases the levels and prolongs the action of these incretin hormones, which enhance insulin secretion and lower glucagon in a glucose-dependent manner, helping maintain better glycemic control.

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✅ Description:

Vildapin is prescribed as an add-on therapy to diet and exercise to help improve blood glucose control in adults with type 2 diabetes mellitus. It may be used:

As monotherapy when diet and exercise alone do not provide sufficient glycemic control.

In combination therapy with Metformin, a Sulfonylurea, a Thiazolidinedione, or Insulin when diet, exercise, and a single oral antidiabetic agent fail to adequately control blood glucose.

Vildagliptin is not recommended during pregnancy.

It should also be avoided during breastfeeding due to insufficient safety data.

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✔️ The usual recommended dose of Vildagliptin depends on the treatment regimen:

Monotherapy:
50 mg or 100 mg once daily

With Metformin or a Thiazolidinedione:
50 mg twice daily (morning and evening)

With a Sulfonylurea:
50 mg once daily in the morning

Vildapin can be taken with or without food.
No dosage adjustments are needed for elderly patients or those with mild renal impairment.

Pediatric use: Not recommended for individuals under 18 years of age.

✔️ Interaction

Clinical studies show no significant interactions with drugs such as pioglitazone, metformin, glibenclamide, digoxin, warfarin, amlodipine, ramipril, valsartan, or simvastatin.
However, similar to other oral antidiabetic agents, the glucose-lowering effect of Vildapin may be reduced when taken with substances like thiazide diuretics, corticosteroids, thyroid medications, and sympathomimetics.

✔️ Vildapin should not be used in patients with:
  1. Known hypersensitivity to Vildagliptin or any excipient
  2. Moderate to severe renal impairment
  3. Hepatic impairment or elevated baseline liver enzymes (ALT/AST > 3× ULN)
  4. Type 1 diabetes mellitus
✔️ Side Effects | Vildapin 50

Most side effects are mild and temporary, rarely leading to treatment discontinuation.
A few isolated cases of liver dysfunction have been reported. Clinical trials lasting over two years have not identified any new or unexpected safety concerns.

✔️ Vildapin 50 | Benefits
  • Vildapin 50 Tablet increases insulin production by the pancreas and decreases glucagon production by the liver. Thus, it helps to control blood sugar levels and prevent further complications due to diabetes.
  • Proper diet and regular exercise, along with Vildapin 50 Tablet, will give better results.
  • Vildapin 50 Tablet should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis.
  • Vildapin 50 Tablet plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss, kidney, damage nerve damage, diabetic foot ulcer, and delayed wound healing.
✔️ Precautions & Warnings
  • Use with caution in patients 75 years or older due to limited data.
  • Liver function tests (LFTs) should be checked before starting therapy, then every 3 months for the first year, and periodically thereafter.
  • If ALT or AST levels remain elevated at 3× ULN, treatment must be discontinued.
  • Stop treatment immediately if jaundice or signs of liver dysfunction appear.
  • Do not restart Vildapin after liver enzymes normalize.
  • Use with caution in patients with NYHA class I–II heart failure; avoid in patients with class III–IV heart failure.
✔️ Storage:

Store below 30°C, protected from light and moisture.
Keep out of the reach of children.

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⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

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