Silten 20mg Tablet

Uses:

• Treats type II diabetes mellitus in adults

How does Silten 20mg Tablet work?

Silten 20mg Tablet reduces blood glucose levels by inhibiting the enzyme dipeptidyl peptidase (DPP)-4, responsible for regulating insulin secretion. By blocking this enzyme, LTEN enhances insulin production, facilitating the breakdown of circulating glucose in the body. Additionally, it regulates post-meal blood sugar levels by controlling the secretion of glucagon.

Side Effects of Silten 20mg Tablet

• Headache
• Hypoglycemia (low blood glucose levels)
• Upper respiratory tract infection
• Nasopharyngitis (infection of the nose and throat with a common cold)

Quick Suggestions:

• Take Teneligliptin at the same time each day to establish a routine and help ensure you don't forget to take it.
• Be cautious when driving or operating machinery until you understand how Teneligliptin affects you. It may have an impact on your alertness and coordination.
• There is a risk of hypoglycemia (low blood sugar) when Teneligliptin is used in conjunction with other antidiabetic medications, alcohol, or if you skip or delay a meal. Pay attention to symptoms such as cold sweats, cool pale skin, tremors, and anxiety.
• To be prepared for potential hypoglycemia, always have sugary food or fruit juice with you. This can be crucial in quickly addressing symptoms.
• Inform your doctor if you experience joint pains or develop symptoms such as stomach pain, nausea, and/or vomiting. Monitoring and discussing any side effects with your doctor is important for appropriate management.

Type 2 Diabetes

Type 2 Diabetes is a condition characterized by the body's inability to produce sufficient insulin or the ineffective utilization of the insulin it produces. Insulin is crucial for regulating blood sugar levels. When the body fails to manage insulin properly, it leads to elevated blood sugar levels, known as hyperglycemia.

Common symptoms of Type 2 Diabetes include increased thirst, frequent urination (especially at night), slow wound healing, heightened hunger, fatigue, and blurred vision. Weight gain is often observed, but in rare cases, there might be weight loss.

Complications associated with Type 2 Diabetes encompass neuropathy (nerve problems), nephropathy (kidney problems), retinopathy (damage to the retina of the eyes, potentially leading to blindness), loss of limbs, sexual dysfunction, and an elevated risk of heart attack or stroke.

Management of Type 2 Diabetes typically involves lifestyle modifications, such as dietary changes and increased physical activity, along with medications and, in some cases, insulin therapy. Regular monitoring and control of blood sugar levels are crucial to prevent or manage the associated complications. Individuals with Type 2 Diabetes often require ongoing medical attention and a comprehensive approach to their overall health.

Pharmacology

• Teneligliptin belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors.
• Inhibits DPP-4, an enzyme that breaks down the hormone 'Incretin.'
• 'Incretins' help stimulate insulin production as needed and reduce liver glucose production when unnecessary.
• Vital in controlling blood sugar levels.
• A preventive measure against serious diabetes complications such as retinopathy, nephropathy, neuropathy, diabetic foot ulcers, and delayed wound healing.
• Teneligliptin is instrumental in managing blood glucose effectively, thereby reducing the risk of severe diabetes-related complications and improving overall patient outcomes.

Dosage & Administration of Silten 20mg Tablet

• Take Silten 20mg Tablet as prescribed by your physician.
• Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.
• It is recommended to take Silten 20mg Tablet preferably after meals.
• Your doctor will determine the appropriate dosage and duration of therapy based on factors such as your age, body weight, and specific medical conditions.
• Do not discontinue taking this medicine without consulting your doctor.

Interaction

Drug-Drug Interaction:

• Interacts with diabetes medications (glipizide, gliclazide, glimepiride).
• Interacts with high blood pressure medications (atenolol, bisoprolol, metoprolol, nadolol, propranolol).
• Interacts with antidepressants (bupropion, selegiline, isocarboxazid, phenelzine).
• Interacts with painkillers (aspirin).

Drug-Food Interaction:

• Excessive alcohol consumption may elevate the risk of Lactic Acidosis. Avoid alcohol intake while using Silten 20mg Tablet.

Drug-Disease Interaction:

• Exercise caution with Silten 20mg Tablet in patients with a history of pancreatitis/pancreatic disease, heart disease, severe ketosis, diabetic coma, history of diabetic coma, severe infection, surgery, and severe trauma.

Contraindications

• Not suitable for patients with type 1 diabetes.
• Not recommended for the treatment of diabetic ketoacidosis.

Pregnancy & Lactation

Silten 20mg Tablet should be used in pregnant women only if prescribed by the physician. Consult your doctor before taking it. Breastfeeding should be stopped during treatment with Silten 20mg Tablet. However, consult your doctor before taking it.

Precautions & Warnings

Avoid taking Teneligliptin if you have an allergy to Teneligliptin or any of its components. Inform your doctor about your pregnancy or breastfeeding status before initiating Teneligliptin. The safety and effectiveness of Teneligliptin in children have not been confirmed, so it is not recommended for pediatric use.

Long-term usage of Teneligliptin may lead to acute pancreatitis (inflammation of the pancreas). There is an increased risk of hypoglycemia (low blood sugar levels) when Teneligliptin is combined with other anti-diabetic medications or insulin therapy. Your doctor may need to adjust the Teneligliptin dosage in such cases.

Some individuals taking Teneligliptin may experience severe allergic reactions, including anaphylaxis, angioedema (skin swelling), and exfoliative skin conditions. Teneligliptin is not suitable for treating type 1 diabetes or diabetic ketoacidosis. Always consult your healthcare provider before using Teneligliptin, especially if you have any of these conditions or concerns.

Storage Conditions

Store in a cool, dry place, away from direct sunlight.