Giane 35 (Box)

Get your orders in 8 hours Dhaka city and 24 hours in other districts! ৮ ঘণ্টায় ঢাকা শহরে ও ২৪ ঘণ্টায় ঢাকার বাহিরে ডেলিভারি

Upload Your Prescription
0 Items
0

Due to the COVID 19 epidemic, orders may be processed with a slight delay

thumbnail

Giane 35 (Box)

Manufacturer/Distributor: Renata Limited

 Generic Name: Cyproterone Acetate 2 mg + Ethinylestradiol 35 mcg 

Indications: This is indicated in Acne, Contraception, Hirsutism, Prostatic carcinoma, Libido, Hot flushes

Generic: Cyproterone Acetate 2 mg + Ethinylestradiol 35 mcg

Type: Tablet

Pack Size: 21pcs


Urgent Delivery 2 Hours Dhaka City
Free Delivery for Order Tk.999+
Cash on Delivery all over Bangladesh

MRP 199.5 8% off
183.54
Inclusive of all taxes




To buy Giane 35 (Box), Click/Tap 'ADD TO BAG' Now.

Get instant Tk.100 Cash back for Tk.500 plus order amount! Use Coupon Code: CASH100 in Checkout page
৫০০ টাকার ঔষধ অর্ডারে ১০০ টাকা ক্যাশব্যাক! এই কুপন কোড: CASH100 টি চেকআউট পেজে ব্যাবহার করুন
Free Delivery

Information about Giane 35 (Box)

Indications of Giane 35

For the treatment of women with severe acne that has not responded to oral antibiotics or other current therapies, as well as androgenization signs such as seborrhea and moderate hirsutism.

 

Pharmaceutical Name

Renata Limited

 

Pharmacology

Cyproterone is a steroid that has antiandrogenic, progestogenic, and antigonadotrophic properties. Its antiandrogenic action is achieved by inhibiting androgen receptors. It also has a negative feedback impact on the hypothalamo-pituitary-ovarian circuits, which decreases androgen production. The estrogen component (Ethinylestradiol) raises levels of sex hormone binding globulin (SHBG) and consequently lowers androgen levels in the blood. SHBG levels are not reduced by cyproterone.

Cyproterone, when administered alone in women, causes menstrual cycle disruptions, which are prevented when coupled with Ethinylestradiol. When taken in a cyclic pattern, this pill offers the extra benefit of preventing ovulation and possible pregnancy.

After oral administration, the components of this tablet are promptly absorbed. After 6 to 12 days of daily dosage, a 4-fold rise in plasma levels occurs due to Cyproterone's lengthy terminal half-life. Long-term treatment with this substance (36 months) had no discernible effect on lipid metabolism. There was a tendency toward higher plasma cholesterol and triglyceride levels. Low density lipoprotein (LDL) levels fell slightly, but high density lipoprotein (HDL) levels rose (HDL).

 

Dosage & Administration

This tablet should not be prescribed solely for its contraceptive properties. If patient compliance is uncertain and contraception is necessary, then a supplementary nonhormonal contraceptive method should be considered.

First Treatment Course: The patient is instructed to take 1 tablet daily for 21 consecutive days beginning on day 1 of her menstrual cycle. (For the first cycle only the first day of menstrual flow is considered Day 1). The tablets are then discontinued for 7 days (1 week). Withdrawal bleeding should usually occur during the period that the patient is off the tablets.The first cycle will be somewhat shorter than usual, whereas all following cycles will last 4 weeks. The patient should be instructed to take the first tablet from the blister pack out of the section marked with the corresponding day (for example "Mon" for Monday) of the week and swallow it with some liquid. The patient should be instructed to take the tablet at the same time each day.

Subsequent Courses: The patient begins her next and all subsequent 21-day course of tablets (following the same 21 days on, 7 days off) on the same day of the week that she began her first course. She begins taking her tablets 7 days after discontinuation,regardless of whether or not withdrawal bleeding is still in progress.

Treatment should be continued for several months,since improvement may not be observed for at least 3 months. The need to continue treatment with This tablet should be evaluated periodically by the treating physician. This drug should be discontinued 3 to 4 cycles after signs have completely resolved.

Pregnancy should be ruled out before continuing treatment with This tablet in patients who have missed a menstrual period, if pregnancy is suspected, medication should be discontinued.

Missed dose: If the patient forgets to take a tablet at the usual time, the tablet may be taken within the next 12 hours. If more than 12 hours have elapsed from the time of usual administration, the patient must discard the missed tablet and continue to take the remaining tablets in the pack at the usual time in order to avoid premature withdrawal bleeding during this cycle. A supplementary nonhormonal method of contraception must be employed until the pack is empty to prevent pregnancy which would necessitate immediate discontinuation of this treatment.

 

Interaction of Giane 35

Ampicillin, analgesics, antihistamines, antimigraine preparations, Chloramphenicol, Griseofulvin, Isoniazid, Neomycin, Nitrofurantoin, Penicillin V, Phenylbutazone, Sulfonamides, and Tetracycline may impair the effectiveness of this pill and raise the risk of breakthrough bleeding if taken together.

When anticoagulants are used with estrogen/progestogen combos, the anticoagulant impact may be reduced. Ampicillin, analgesics, antihistamines, antimigraine preparations, Chloramphenicol, Griseofulvin, Isoniazid, Neomycin, Nitrofurantoin, Penicillin V, Phenylbutazone, Sulfonamides, and Tetracycline may impair the effectiveness of this pill and raise the risk of breakthrough bleeding if taken together.

When anticoagulants are used with estrogen/progestogen combos, the anticoagulant impact may be reduced. Anti-diabetic medicine may need to be adjusted for diabetics who use estrogen/progestogen combos. It has been observed that taking vitamin C (ascorbic acid) with estrogen/progestogen combinations causes a substantial increase in plasma Ethinylestradiol levels.

Before starting therapy, be sure you're not pregnant. Feminization of male fetuses has happened in animal studies and may occur in humans due to the antiandrogenic effect of this pill.

 

Contraindications

Thrombophlebitis, thromboembolic diseases, or a family history of them

Cerebral vascular disease

Coronary artery disease or myocardial infarction

Hepatic adenomas or carcinomas, as well as active liver disease

cholestatic jaundice in the past

Breast cancer that is known or suspected

Estrogen-dependent neoplasia that is known or suspected

Abnormal vaginal hemorrhage that has gone undiagnosed

Any eye lesion caused by ophthalmic vascular disease, such as partial or total blindness or visual field defects.

If you think you're pregnant or have been told you are,

Tumors in the liver that have previously been or are now present

Diabetes mellitus with vascular alterations

Otosclerosis with worsening during pregnancy is a history.

 

Side Effect

Bleeding, dizziness, depression, weight gain, headache, edema, breast discomfort, lactation, blood clot, and gallstones are all common adverse effects.

 

Pregnancy & Lactation

The kids of women who used estrogen/progestogen combos in early pregnancy have been documented to develop fetal defects. As soon as you suspect pregnancy, rule it out. It's possible that using estrogen/progestogen combos when a woman is breast-feeding her baby isn't a good idea. The hormonal components are expelled in breast milk, which might affect the amount and quality of the product. The long-term consequences on a child's development remain unknown. Fluid retention, as well as epilepsy, are possible side effects of this medication.

 

Precautions & Warnings

Predisposing Factors for Coronary Artery Diseases: The use of estrogen or progestogen combinations has been reported as an additional risk factor in women with predisposing factors for coronary artery disease (such as cigarette smoking, hypertension, hypercholesterolemia, obesity, diabetes, and increasing age). After the age of 35, estrogen or progestogen combinations should only be considered in rare circumstances and after both the patient and the physician have carefully analyzed the risk/benefit ratio.

Thromboembolic and cardiovascular diseases such as thrombophlebitis, pulmonary embolism, cerebrovascular disorders, myocardial ischemia, mesenteric thrombosis, and retinal thrombosis should be stopped as soon as possible. In situations that predispose to venous stasis and vascular thrombosis, such as immobilization following accidents or confinement to bed during long-term sickness, the use of estrogen/progestogen-combination products should be avoided.

Patients with essential hypertension who have well-controlled blood pressure may be administered the medication, but only under strict monitoring. If a substantial increase in blood pressure develops in previously normotensive or hypertensive individuals at any point during the drug's treatment, the medication must be stopped.

 

Therapeutic Class

Oral Contraceptive preparations, Oral Hormonal preparations for Acne

 

Storage Conditions

Keep away from light and moisture in a cool, dry area (below 30° C). Keep out of children's reach.

 

 

Ratings & Reviews

No review

Check our pricing section for Giane 35 (Box) price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confermation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Similar Products

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability
ePharma reserves the right to make adjustments to pricing, Products and Service offerings for reasons including, but not limited to, changing market conditions, Product discontinuation, Product unavailability, manufacturer price changes, supplier price changes and errors in advertisements. All orders are subject to Product availability and the availability of Personnel to perform the Services. Therefore, Seller cannot guarantee that it will be able to fulfill Customer’s orders. If Services are being performed on a time and materials basis, any estimates provided by Seller are for planning purposes only.