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Drops Manufacturer/Distributor: Drug International Ltd. Generic Name: Ketotifen .025 % Eye Drops
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✅ Description:
Indications
Ketotifen eye drop is used to treat the signs and symptoms of allergic conjunctivitides, such as vernal keratoconjunctivitis, vernal keratitis, blepharitis, blepharoconjunctivitis, and giant papillary conjunctivitis (itchy, watery, red, swollen eyes and eyelids).
Pharmacology
Ketotifen is a powerful anti-allergic drug that blocks histamine (H1) receptors in a non-competitive and long-lasting manner. Ketotifen works by preventing the release of mediators (such as histamine, leukotrienes, and prostaglandins) from cells that cause type I allergic reactions. Ketotifen also stabilizes mast cells, reduces chemotaxis, and activates eosinophil degranulation.
Dosage & Administration
Adults and children 3 years and older: 1 drop in the affected eye(s) twice daily, every 8-12 hours, not more than twice per day.
Children under 3 years of age: Consult with a doctor.
Interaction
If Ketotifen eye drops are taken in conjunction with other eye treatments, at least 5 minutes must pass between the two medications.
Contraindications
Hypersensitivity to Ketotifen or any of the components
Side Effects
Burning, stinging, punctate corneal epithelial erosion, blurred vision after drug instillation, dry eyes, eyelid dysfunction, conjunctivitis, eye pain, photophobia, and subconjunctival hemorrhage are all common adverse effects.
Pregnancy & Lactation
There is insufficient information about the usage of ketotifen eye drops in pregnant women. Systemic levels are significantly lower after ocular administration than after oral treatment. Prescriptions for pregnant women should be handled with caution. Although animal research shows excretion into breast milk after oral administration, topical application to humans is unlikely to yield detectable amounts in breast milk. During lactation, ketotifen 0.25 percent eye drops can be utilized.
Precautions & Warnings
Because benzalkonium chloride, a preservative in the formulation of Ketotifen 0.025 percent eye drops, might deposit in soft contact lenses, this eye drop should not be used when the patient is wearing lenses. The lenses should be removed before using the drops and should not be reinserted for at least 15 minutes afterward.
Storage Conditions
Store in a cool and dry place protected from light and moisture. Keep out of reach of children. Do not touch the dropper tip to any surface since this may contaminate the solution. Do not use after 30 days of first opening.
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