Trimet 20mg Tablet

Uses of Trimet 20mg Tablet

• Angina Pectoris

How does Trimet 20mg Tablet work?

Trimet 20mg Tablet functions by optimizing the metabolism of fatty acids and glucose, thereby augmenting blood flow and oxygen supply to the heart. It also diminishes the thickening and scarring of heart tissue. This combined effect leads to the reduction of chest pain due to blood vessel narrowing or blockage.

Side Effects of Trimet 20mg Tablet

Common

• Dizziness
• Headache
• Abdominal pain
• Diarrhea
• Vomiting
• Indigestion
• Nausea
• Rashes, itching, hives
• Feeling of weakness

Rare

• Rapid or irregular heartbeats

In case you experience any of the following signs, immediately cease Trimet 20mg Usage and consult your doctor:

• Indications of low blood pressure, such as dizziness, light-headedness, fainting, malaise, falls flushing
• Signs of low platelet count (thrombocytopenia), including easy bruising, superficial bleeding, and prolonged bleeding from wounds
• Decreased white blood cell count, which heightens vulnerability to infections

Quick Suggestions:

• Trimet 20mg Tablet prevents new angina attacks but does not stop acute attacks.
• It does not impact heart rate or blood pressure at rest or during exercise.
• Trimet 20mg Tablet can improve HbA1c and blood sugar levels in diabetes patients.
• Adopt a healthy diet rich in soluble fiber from sources like beans, legumes, whole grains, flax, apples, and citrus fruits.
• Consider following a Mediterranean-style diet with olive oil, fruits, vegetables, nuts, whole grains, fish, and limited red meat and dairy.
• Prioritize consuming more fruits and vegetables for their antioxidant content.
• Minimize added sugar intake. American Heart Association recommends specific daily limits for men, women, and children.
• Limit sodium intake to no more than 2,300 mg of table salt per day as part of a healthy eating pattern.

Indication of Trimet 20mg Tablet

Trimet 20mg Tablet contains the active ingredient Trimetazidine, which functions as a 'metabolic agent.' This compound impacts metabolism, which is the process of breaking down substances in the body. By altering metabolism, Trimet 20mg Tablet reduces the body's demand for oxygen by transitioning the metabolic process from utilizing fats to utilizing glucose. This adjustment results in an improved efficiency of the heart's function and a decreased requirement for oxygen.

Furthermore, besides its role in treating angina and improving cardiac efficiency, Trimetazidine is also utilized in the management of other conditions. It is employed to address vertigo, characterized by a spinning sensation, as well as tinnitus, which involves a ringing sensation in the ears. Additionally, Trimetazidine is used to alleviate issues related to reduced vision and disturbances in the visual field, which can manifest as unclear or disrupted vision.

Pharmacology

Trimetazidine Dihydrochloride operates as a metabolic anti-ischemic drug that offers notable benefits for individuals with cardiac concerns. It functions by inhibiting the fatty acid pathway and directing oxygen toward the glucose pathway through the inhibition of the 3-ketoacyl CoA thiolase enzyme—a process facilitated by its action as a 3-ketoacyl CoA thiolase inhibitor (KAT).

This redirection of energy metabolism to the glucose pathway proves to be more efficient. As a result, despite utilizing the same amount of oxygen, more energy is generated, consequently leading to an increased heart rate. Moreover, the oxidation of glucose in an aerobic manner curbs the accumulation of lactic acid, which in turn serves to prevent the occurrence of angina pectoris—an outcome that holds significant therapeutic value for individuals grappling with this condition.

Dosage & Administration of Trimet 20mg Tablet

The standard dosage of Trimetazidine is typically 35 mg taken twice daily, or alternatively, a 20 mg tablet can be taken three times daily during meals.

Administer Trimet 20mg Tablet as directed by your physician. Swallow the medicine with water, refraining from crushing or chewing it. Your doctor will determine the appropriate dosage and duration based on factors such as your age, body weight, and medical condition.

Interaction

Before initiating the Trimet 20mg Tablet, inform your doctor about other medications you are taking, including those acquired without a prescription.

Contraindications

Contraindications include hypersensitivity to the active ingredient or any excipients, and the medicine is not recommended for individuals with Parkinson's disease, Parkinsonian symptoms, tremors, restless legs syndrome, or significant renal impairment.

Pregnancy & Lactation

Regarding pregnancy, there is no available information about Trimetazidine's use in pregnant women. Animal studies suggest no direct or indirect adverse effects on reproduction. However, as a precaution, it is advised to avoid using Trimetazidine during pregnancy. While Trimetazidine is not known to be excreted in human milk, a potential risk to neonates and infants cannot be ruled out. Breastfeeding mothers are advised to avoid taking Trimetazidine.

Precautions & Warnings

Do not consume Trimet 20mg Tablet if you:

• Suffer from Parkinson's disease (characterized by movement difficulties)
• Fall under the pediatric age group
• Are above 75 years old (geriatric age group)

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.