Radiflex Rapid 40mg+50mg+100mg+60mg Capsule

Radiflex Rapid capsule is indicated for the treatment and prevention of-
 

• Osteoporosis
• Osteoarthritis
• Osteomalacia
• Osteopenia
• Pain & Inflammation Associated with Musculoskeletal and Joint Disease
• Joint Immobility and Rigidity
• Rheumatoid Arthritis
• Strenuous Exercise and Sports Injury

* রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'

Composition

Each Radiflex Rapid capsule contains-
 

• Undenatured Collagen-II USP 40 mg
• Hyaluronic Acid 50 mg as Sodium Hyaluronate BP
• Boswellia Serrata USP 100 mg and
• Vitamin C 60 mg as Ascorbic Acid USP.

Each Hybocare capsule contains-
 

• Undenatured Type-ll Collagen 40 mg
• Hyaluronic Acid (as Sodium Hyaluronate) 50 mg
• Boswellia Serrata Extract 100 mg and
• Ascorbic Acid (Vitamin C from Corn Extract) 60 mg.

Description

Undenatured Collagen II is a protein that is part of the cartilage, bone & other types of connective tissues. Collagen II, like all collagen, is made up of three chains of amino acids: glycine, proline, and hydroxyproline, which is known as a triple helix.

Undenatured Collagen II is a nutritional supplement derived from chicken sternum cartilage using a patented, low-temperature, non-enzymatic manufacturing process that preserves the natural triple helix molecular configuration and its biological activities.

Boswellic acid is the active ingredient in Boswellia serrata which has significant pharmacological activity in the treatment of inflammatory diseases such as rheumatoid arthritis and other inflammatory conditions. Research showed that 3-0-Acetyl-11-keto-beta-boswellic acid (AKBA), present in Boswellia serrata extract, has a powerful inhibitory effect on 5-lipoxygenase (5-LOX). 

Hyaluronic Acid binds well to water, producing a viscous, jelly-like consistency. This viscous fluid provides lubrication and also acts as a shock absorber within the joint. Growth of cartilage and bone; Hyaluronic acid helps in the growth and development of joint’s cartilage and bone by promoting the growth of new cells and tissues. Reducing inflammation: Hyaluronic acid plays an important role in reducing joint inflammation and pain caused by injury or tissue degeneration. 

Vitamin C is an antioxidant that helps to prevent oxidative stress-induced chondrocyte dysfunction. It’s also needed for the growth and repair of tissues throughout the body, including the formation of collagen, which is used to make skin, tendons, ligaments and blood vessels.

Pharmacology

Collagen II acts as an antigen, causing an autoimmune response that stimulates the production of anti-inflammatory cell-signaling proteins called cytokines. Undenatured Collagen II has a unique mechanism of action. Undenatured Collagen II molecules contain active binding sites called epitopes which trigger the process of oral tolerization. Through the oral tolerization process, active epitopes of Undenatured Collagen II interact with Peyer’s patches (lymphoid tissue) of the small intestine to release collagen-specific regulatory T-cells. Collagen-specific regulatory T-cells then migrate to joint areas and prevent the release of T-cells. Preventing the release of T-cells prevents the secretion of collagenase enzymes by macrophages responsible for the breakdown of collagen in joint cartilage. It also slows the production of inflammatory cytokines resulting in the reduction of inflammation, halting the erosion of joint cartilage, and promoting cartilage rebuilding. Undenatured Collagen II supports joint function, mobility, and flexibility and also improves knee extension by up to 10% for a better range of motion. It also relieves joint pain due to strenuous exercise. Chicken collagen also contains chondroitin & glucosamine which help in rebuilding cartilage The resinous part of Boswellia serrata possesses monoterpenes, diterpenes, triterpenes, tetracyclic triterpene acids and four major pentacyclic triterpene acids i.e. P-boswellic acid, acetyl-p-boswellic acid, 11-keto-p-boswellic acid & acetyl-11-keto-p-boswellic acid, responsible for inhibition of pro-inflammatory enzymes. Hyaluronic acid binds with CD-44 Receptor, reduces Proinflammatory Signals & increases lubrication and shock absorption. Vitamin C increases hydroxylation of proline & increases synthesis of procollagen and bone mineral density.

Dosage & Administration

Orally, 1 capsule daily after a meal with water or as directed by the physician.

* রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'

Interaction

Caution should be practiced when administering Hyaluronic Acid, Boswellia Serrata and Vitamin C concomitantly with anticoagulants. Hyaluronic Acid can alter the gastrointestinal absorption of certain antibiotics. Radiflex Rapid can be used concomitantly with analgesics or anti-inflammatory drugs.

Contraindications

Contraindicated in patients with known hypersensitivity to Undenatured Collagen II. Hyaluronic Acid, Boswellia Serrata and Vitamin C. Not recommended for patients under 12 years of age and for patients with phenylketonuria or severe renal insufficiency. Dose adjustment of antidiabetic drugs may be needed as Boswellia Serrata may lower blood glucose level.

Side Effects

Generally well-tolerated at the recommended dose. Occasionally, mild epigastric pain. constipation, diarrhea, bloating, and nausea may occur. Rarely, headache and visual disturbance may occur.

Pregnancy & Lactation

Scientific information is limited on the use of Undenatured Collagen II, Hyaluronic Acid, Vitamin C & Boswellia Serrata Extract during pregnancy or lactation.

Therapeutic Class

Drugs for Osteoarthritis, Herbal and Nutraceuticals

Storage Conditions

Do not store above 30°C. Protect from light and moisture. Keep out of reach of children