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Generic Name: Ciprofloxacin 500mg
Manufacturer/Distributor: Acme Laboratories Ltd.
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✅ Description:
Indications of Cipro-A 500 Tablet
Ciprofloxacin is used to treat a variety of infections, including respiratory tract infections, urinary tract infections, pelvic inflammatory diseases, infectious diarrhea (such as Shigella dysenteriae and Vibrio cholera), typhoid fever, prostatitis, intra-abdominal infections, gonorrhea, and infections of the bones and joints.
Pharmacology of Cipro-A 500 Tablet
The fluoroquinolone antibiotic ciprofloxacin is produced synthetically. With regard to both gram-positive and gram-negative bacteria, it demonstrates the bactericidal effect. It prevents the synthesis of bacterial DNA by interacting with the DNA supercoiling enzymes DNA gyrase and topoisomerase IV.
Dosage & Administration of Cipro-A 500 Tablet
Tablet: Adult:
- Respiratory Tract Infections: 500 to 750 mg twice daily (7 to 14 days)
- Urinary tract infections: 250 to 750 mg twice daily (3 to 10 days)
- Pelvic Inflammatory Diseases: 500 to 750 mg twice daily (14 days)
Infectious Diarrhea (Shigella dysenteriae, Vibrio cholera):
- 500 mg twice daily (1 to 5 days)
Typhoid fever:
- 500 mg twice daily (7 days)
Intra-abdominal infections:
- 500 to 750 mg twice daily (5 to 14 days)
Prostatitis:
- 500 to 750 mg twice daily (2 to 6 weeks)
Skin and Soft Tissue Infections:
- 500 to 750 mg twice daily (7 to 14 days)
Bone and Joint Infections:
- 500 to 750 mg twice daily (max. 3 months)
Gonorrhea:
- 500 mg as a single dose
Neutropenic patients with fever due to bacterial infection:
- 500 to 750 mg twice daily co-administered with appropriate antibacterials.
Meningitis:
- 500 mg as a single dose.
Surgical prophylaxis:
- 500 mg as a single dose, 60 minutes before the procedure.
Suspension: Pediatric:
- 10-20 mg/kg (max. 750 mg) twice daily (10 to 21 days). The duration of therapy depends on the type and severity of the infection.
Interaction of Cipro-A 500 Tablet
Ciprofloxacin shouldn't be taken at the same time as antacids that contain magnesium or aluminum, sucralfate, or any medications that contain calcium, iron, or zinc. Ciprofloxacin can be taken before or after these products, but not within two hours of them. Because the absorption of Ciprofloxacin may be significantly reduced when consumed with milk or other dairy products, it should not be taken with them. However, dietary calcium consumed with a meal has no impact on how well Ciprofloxacin is absorbed.
Contraindications
Patients who have a known hypersensitivity to Ciprofloxacin or other quinolones should avoid it.
Side Effects of Cipro-A 500 Tablet
- Nausea
- Gastrointestinal disorders,
- Headache,
- Dizziness,
- Joint pain
- Skin rashes
Pregnancy & Lactation
In pregnant women, there are no sufficient and well-controlled trials. Only if the possible benefit outweighs the danger to the fetus and mother should Ciprofloxacin be used during pregnancy. Human milk contains ciprofloxacin, which is excreted. Ciprofloxacin should not be taken during lactation due to the risk of articular injury.
Precautions & Warnings
Patients using Ciprofloxacin should be encouraged to drink plenty of water. In individuals with suspected or established CNS problems, such as epilepsy, or other variables that predispose to seizures and convulsions, it should be administered with caution. Hypokalemia should be avoided in patients with known QT prolongation.
Storage Conditions
Keep the temperature below 30°C and keep it away from light and moisture. Keep out of children's reach.
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