RivaXa 10mg 10pcs
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RivaXa 10mg 10pcs

Generic: Rivaroxaban

Type: Tablet

Pack Size: 10 Pcs

Generic Name: Rivaroxaban 10mg

Company Name: Square Pharmaceuticals Limited


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Discount Price: ৳ 232.5
MRP: ৳ 250 7% Off

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Description:

Indications

Rivaroxaban 2.5 mg: For the prevention of atherothrombotic events in adult patients with increased cardiac biomarkers following an Acute Coronary Syndrome (ACS) (Troponin or CK-MB). It is used in combination with aspirin alone, aspirin + Clopidogrel, or Tidopidine.

Rivaroxaban 10-20 mg: Rivaroxaban 10-20 mg: Rivaroxaban 10-20

In individuals with nonvalvular atrial fibrillation, to minimize the risk of stroke and systemic embolism.

Deep vein thrombosis (DVT) and pulmonary embolism (PE), as well as the risk of DVT and PE recurrence.

In patients having knee or hip replacement surgery, for the prevention of DVT, which can progress to PE.

Pharmacology

Rivaroxaban is a direct factor Xa inhibitor with high selectivity. Factor Xa inhibition reduces thrombin production by interrupting the intrinsic and extrinsic pathways of the blood coagulation cascade. Rivaroxaban has been shown to have no impact on platelets and does not block thrombin (activated factor II).

Dosage & Administration

Rivaroxaban 2.5 mg:

The recommended dose: is 2.5 mg twice daily. Patients should also take a daily dose of 75-100 mg Aspirin or a daily dose of 75-100 mg Aspirin in addition to either a daily dose of 75 mg clopidogrel or a standard daily dose of ticlopidine.

Rivaroxaban 10-20 mg:

Nonvalvular Atrial Fibrillation: For patients with Creatinin Clearance >50 mL/min: 20 mg orally, once daily with the evening meal. For patients with Creatinin Clearance 15-50 ml/min: 15 mg orally, once daily with the evening meal.

Treatment of DVT & PE: 15 mg orally twice daily with food for the first 21 days for the initial treatment of acute DVT or PE. After the initial treatment period, 20 mg orally once daily with food for the remaining treatment.

Prevention in the risk of recurrence of DVT and of PE: 20 mg once daily with food.

Prophylaxis of DVT following Hip replacement surgery: 10 mg once daily for 35 days.

Prophylaxis of DVT following knee replacement surgery: 10 mg once daily for 12 days.

May be taken with or without food.

Interaction

Rivaroxaban exposure and pharmacodynamic effects (factor Xa inhibition and PT prolongation) are increased when used with medicines that are a combination P-gp and CYP3A4 inhibitors (ketoconazole, ritonavir, clarithromycin, erythromycin, fluconazole, diltiazem, verapamil, dronedarone). Rivaroxaban should not be used with a combination P-gp and strong CYP3A4 inducer (e.g., rifampicin, phenytoin, carbamazepine) since it reduces the effectiveness of Rivaroxaban. The use of antiplatelet medicines, heparin, fibrinolytic treatment, and NSAIDs at the same time may increase the risk of bleeding.

Contraindications

It is not recommended for patients who have a known hypersensitivity to RivaXa 10 or any of the product's excipients. It is also not recommended for individuals who are experiencing active pathological bleeding.

Side Effects

Increased risk of bleeding, spinal or epidural hematoma, and increased risk of stroke after cessation in nonvalvular atrial fibrillation are the most prevalent adverse effects of RivaXa 10.

Pregnancy & Lactation

RivaXa 10 is classified as a pregnancy Category C medication. Rivaroxaban has not been studied in pregnant women insufficient or well-controlled trials, and dosage for pregnant women has not been established. RivaXa 10 is not known to be excreted in human milk. Rivaroxaban's safety and effectiveness in nursing mothers have yet to be determined.

Precautions & Warnings

Premature discontinuation of RivaXa 10, in the absence of adequate alternative anticoagulation, increases the risk of thrombotic events. Rivaroxaban increases the risk of bleeding that can be fatal in presence of the following risk factors- bleeding disorders, uncontrolled severe arterial hypertension, gastrointestinal disease (e.g., inflammatory bowel disease, oesophagitis, gastritis, and gastroesophageal reflux disease), vascular retinopathy, bronchiectasis, history of pulmonary bleeding, Signs or symptoms of neurological impairment should be monitored in case of neuraxial anesthesia (spinal/epidural anesthesia) or spinal puncture as epidural or spinal hematoma can occur. Rivaroxaban is not recommended in patients with pulmonary embolism who present with hemodynamic instability or who may receive thrombolysis or pulmonary embolectomy.

Storage Conditions

Do not store above 30° C. Keep away from light and out of the reach of children.

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Check our pricing section for RivaXa 10mg 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

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