Generic Name: Fexofenadine Hydrochloride 120mg
Manufacturer/Distributor: Acme Laboratories Ltd.
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Indications
Fexofenadine Hydrochloride is used to treat the symptoms of seasonal allergic rhinitis in both adults and children. It's also used to treat the cutaneous signs of chronic idiopathic urticaria that aren't too severe.
Pharmacology
Fexofenadine Hydrochloride is an antihistamine that works by blocking peripheral H1 receptors. After oral administration, it is rapidly absorbed and reaches maximal plasma concentration in 2-3 hours. It doesn't appear to be able to pass through the blood-brain barrier.
Dosage & Administration
Seasonal Allergic Rhinitis-
Adults and children 12 years and older:
Children from 6 to 11 years:
Suspension: 30 mg or 5 ml twice daily
In case of impaired renal function: 30 mg or 5 ml once daily
Chronic Idiopathic Urticaria-
Adults and children 12 years and older:
Children from 6 to 11 years:
Children from 6 months to less than 2 years:
Children from 2 to 11 years:
Interaction
When taken with erythromycin or ketoconazole, the plasma levels of Fexofenadine Hydrochloride increased. Fexofenadine Hydrochloride absorption is reduced by antacids that contain aluminum and magnesium hydroxide.
Contraindications
Patients who have a known hypersensitivity to Fexofenadine Hydrochloride or any of its constituents should not take it.
Side Effects
Headache, lethargy, drowsiness, nausea, dry mouth, and gastrointestinal disorders are all common adverse effects.
Pregnancy & Lactation
Fexofenadine Hydrochloride is classified as pregnancy category C by the US Food and Drug Administration. So, unless the potential benefits to the other outweigh the potential hazards to the fetus, Fexofenadine Hydrochloride should be avoided during pregnancy and lactation.
Precautions & Warnings
Patients who are elderly or have impaired renal function should be treated with caution.
Storage Conditions
Keep away from light and heat in a dry location. Keep out of children's reach.