Nitrin SR 2.6mg Tablet 10pcs

Uses of Nitrin SR 2.6mg Tablet

• Used for prevention of Angina Pectoris (Chest Pain) due to coronary artery disease

How does Nitrin SR 2.6mg Tablet work?

Nitrin SR 2.6mg Tablet causes relaxation of smooth muscles within blood vessels which leads to relaxation and widening of blood vessels. This improves blood supply to the heart muscles. As a result, it helps to relieve chest pain and blood pressure.

Side Effects of Nitrin SR 2.6mg Tablet

• Blurred vision
• Decreased blood pressure
• Dizziness
• Headache
• Increased heart rate
• Lightheadedness
• Paresthesia (tingling or pricking sensation)

Quick Suggestions:

• Nitrin SR 2.6mg Tablet may cause dizziness or sleepiness. It is important to avoid driving or engaging in activities that require concentration until you know how the medication affects you.
• Alcohol should be avoided while taking Nitrin SR 2.6mg Tablet as it may increase dizziness and worsen side effects.
• Headaches are a common side effect of Nitrin SR 2.6mg Tablet, but they typically improve after a few days of continued treatment. If headaches persist or worsen, it is important to inform your doctor.
• Following a cholesterol-lowering diet is recommended while taking Nitrin SR 2.6mg Tablet. This includes consuming a low-salt and low-fat diet, choosing healthy fats, reducing trans-fat intake, including omega-3 fatty acids, and increasing fiber-rich foods, fruits, and vegetables in your diet.
• If you are taking medications for erectile dysfunction such as sildenafil or tadalafil, it is advised to stop taking them while on treatment with Nitrin SR 2.6mg Tablet, as they may cause low blood pressure when combined.
• Regular exercise is beneficial for maintaining proper weight, lowering cholesterol levels, and overall cardiovascular health. Activities such as swimming, brisk walking, jogging, and taking the stairs instead of elevators/lifts are encouraged.
• It is important to limit salt and sugar intake, avoid smoking, and moderate or avoid alcohol consumption for optimal health benefits.

Indication of Nitrin SR 2.6mg Tablet

Nitrin SR 2.6mg Tablet is an orally administered vasodilator (it helps to enlarge blood vessels) used to treat angina. 

Angina is a type of chest pain or discomfort caused by a lack of oxygen-rich blood to your heart muscle. The symptoms are chest discomfort, tightness, or heaviness. It might be abrupt or recurring. Nitrin SR 2.6mg Tablet may help to prevent and alleviate chest discomfort by expanding blood vessels and boosting blood and oxygen delivery to the heart.

Nitrin SR 2.6mg Tablet alleviates angina by relaxing the blood vessels around the heart. Additionally, it allows more blood and oxygen to reach your heart muscles. Nitrin SR 2.6mg Tablet does not address the underlying cause of your chest discomfort, but it does assist to alleviate the symptoms.

Pharmacology

In peripheral arteries and veins, nitroglycerin has vasodilator effects and relaxes smooth muscle. The venous expansion increases peripheral blood accumulation, decreases venous return to the heart, lowers left ventricular end-diastolic pressure (preload), and arterial relaxation lowers blood pressure and systemic vascular resistance (afterload).

Dosage & Administration of Nitrin SR 2.6mg Tablet

The adult dosing recommendations for Nitrin SR 2.6mg Tablet in different forms and indications are as follows:

Oral (Stable angina):

• Extended-release tablets/capsules: 2.6-6.4mg, taken 3-4 times daily. The dose can be adjusted based on the individual's response. The maximum recommended dose is 26mg taken 4 times daily.

Sublingual Tablet (Angina Pectoris - Acute Relief):

• 0.5mg sublingual tablet can be taken every 5 minutes up to 3 times. It should be used at the first sign of angina.

Sublingual Tablet (Angina Pectoris - Prophylaxis):

• 1 tablet (dose not specified) should be taken sublingually 5-10 minutes before activities that are likely to trigger angina attacks.

For patients with renal failure:

• In patients with a creatinine clearance (CrCl) of 10-50mL/min, Nitrin SR 2.6mg Tablet should be administered every 24-72 hours.
• In patients with a CrCl of less than 10mL/min, Nitrin SR 2.6mg Tablet should be administered every 72-96 hours.

Always use Nitrin SR 2.6mg Tablet exactly as prescribed by your doctor.

For Tablet, Capsule: Swallow Nitrin SR 2.6mg Tablet with a glass of water. Do not crush or chew the medicine.

For Sublingual Tablet: Place Nitrin SR 2.6mg Tablet inside your mouth, below the tongue and allow it to dissolve completely. Do not swallow or chew the medicine.

Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and severity of your disease condition. Continue to take Nitrin SR 2.6mg Tablet for the stipulated duration prescribed by your doctor to achieve better results.

Interaction

Before taking Nitrin SR 2.6mg Tablet, it is important to inform your doctor if you are taking any of the following medications:

• Medications for erectile dysfunction (male impotence) such as sildenafil, vardenafil, or tadalafil.
• Medications used to treat paracetamol overdose, such as n-acetylcysteine.
• Medications for migraine, such as ergotamine.
• Other nitrates are used to treat heart diseases, such as isosorbide dinitrate, isosorbide mononitrate, or disopyramide, as well as medications for high blood pressure like ramipril or atorvastatin.
• Medications used to thin the blood and prevent blood clots, such as warfarin.
• Medications used to treat Parkinson's disease, such as apomorphine.
• Medications used to treat stomach ulcers, such as propantheline.
• Medications are used to treat anxiety and depression, such as amitriptyline or isocarboxazid.

It is important to disclose all the medications you are taking to your doctor to avoid any potential interactions between Nitrin SR 2.6mg Tablet and other drugs. Your doctor will consider these factors and adjust your treatment plan accordingly.

Contraindications

• Hypersensitivity: If you have a known hypersensitivity or allergy to Nitrin SR 2.6mg Tablet or any of its ingredients, it should be avoided.
• Severe hypotension: If you have severely low blood pressure, Nitrin SR 2.6mg Tablet should not be used as it may further decrease blood pressure.
• Heart failure: If you have heart failure, Nitrin SR 2.6mg Tablet should be avoided as it may worsen the condition.
• Marked anaemia: In cases of severe anemia, the use of Nitrin SR 2.6mg Tablet is contraindicated.
• Hypertrophic obstructive cardiomyopathy: Nitrin SR 2.6mg Tablet should not be used in individuals with hypertrophic obstructive cardiomyopathy, a condition where the heart muscle becomes abnormally thickened, as it may worsen the symptoms.
• Cerebral hemorrhage or head trauma: Nitrin SR 2.6mg Tablet is contraindicated in individuals with cerebral hemorrhage (bleeding in the brain) or recent head trauma.
• Low cardiac output secondary to hypovolemia: If you have low cardiac output due to hypovolemia (low blood volume), the use of Nitrin SR 2.6mg Tablet is contraindicated.

Inferior myocardial infarction (heart attack) with right ventricular involvement: Nitrin SR 2.6mg Tablet should be avoided in individuals with this specific type of heart attack.

Raised intracranial pressure: If you have increased pressure within the skull, Nitrin SR 2.6mg Tablet should not be used.

Concomitant use with phosphodiesterase type-5 inhibitors: Nitrin SR 2.6mg Tablet should not be taken together with medications belonging to the class of phosphodiesterase type-5 inhibitors, such as sildenafil, vardenafil, or tadalafil, commonly used for erectile dysfunction. The combination of these medications can lead to a significant drop in blood pressure.

Pregnancy & Lactation

Unless the doctor considers it necessary, nitroglycerin should not be used during pregnancy or breastfeeding.

Precautions & Warnings

Do not take Nitrin SR 2.6mg Tablet if you are allergic to nitrates or any of its ingredients. It is important to inform your doctor about all other over-the-counter medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take, as they may interact with Nitrin SR 2.6mg Tablet.

If you have kidney problems, a history of heavy alcohol consumption, anemia, or have had a recent heart attack, Nitrin SR 2.6mg Tablet should be taken cautiously and only under the supervision of a doctor.

Before starting Nitrin SR 2.6mg Tablet, inform your doctor if you are pregnant or breastfeeding, as a dose adjustment may be necessary based on the potential risks and benefits.

It is worth noting that Nitrin SR 2.6mg Tablet may cause dizziness, light-headedness, and fainting, especially when you get up too quickly from a lying position. This effect is more likely when you start taking Nitrin SR 2.6mg Tablet. To minimize these symptoms, it is advised to get up gradually and avoid sudden movements.

Storage Conditions

Store in a cool and dry place away from light and heat. Keep all medicines out of the reach of children.