Ferroglobin Syrup

Uses of Ferroglobin Syrup

• Iron Deficiency
• Anemia

How does Ferroglobin Syrup work?

Iron is vital for the formation of new red blood cells and hemoglobin, a substance that gives these cells the ability to transport oxygen.

Side Effects of Ferroglobin Syrup

• Diarrhea
• Constipation
• Nausea
• Stomach pain
• green-colored stools
• Loss of appetite

Quick Suggestions:

• Take it as per the dose and duration suggested by the doctor.
• Avoid drinking alcohol while taking this medicine as it may worsen the side effects.
• You may be asked for regular blood tests to check for blood cells and iron levels in the body.
• It might cause a lowering of blood pressure. Continuous monitoring of blood pressure is required while taking this medicine.
• Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
• Liquid preparations of ferrous sulfate may stain teeth.

Indication of Ferroglobin Syrup

Ferroglobin Syrup is used in the treatment of iron deficiency anemia and anemia due to chronic kidney disease. 

• Useful for iron deficiency and anemia
• May improve energy levels
• Boosts immune function
• Supports overall health

Pharmacology

Ferrous sulfate promotes O2 transport through hemoglobin. It is used as a source of iron because it replaces the iron found in hemoglobin, myoglobin, and other enzymes.

Dosage & Administration of Ferroglobin Syrup

Adults:

• Initial Therapeutic Dose: 3-4½ teaspoonfuls daily in divided doses or as prescribed by a physician.
• Maintenance Dose: 1½ teaspoonful daily. If needed, the dose can be increased up to 1.8g (9 teaspoonfuls) daily.

Children:

• Under 1 year: ¼ teaspoonful thrice daily or as directed by a physician.
• 1-5 years: 1 teaspoonful thrice daily.
• 6-12 years: 1½ teaspoonful twice daily.

Elderly:

• Ferrous sulfate administration should be avoided for periods longer than 6 months, except in patients with continuous bleeding.

General Usage Notes:

• The supplement should ideally be taken on an empty stomach.
• It can be taken with meals to reduce gastrointestinal discomfort.
• Mixing with water or fruit juice is recommended to avoid temporary staining of teeth.
• Do not mix with milk.

Interaction

Interactions That May Reduce Iron Absorption:

Antacids/H2 Antagonists: Concurrent administration with antacids or H2 antagonists (medications that reduce stomach acid production) can decrease the absorption of iron. This is because stomach acid helps in the breakdown and absorption of iron.

Chloramphenicol: Chloramphenicol, an antibiotic, can delay the response to iron. This means that the effect of iron supplementation might be less pronounced when taken alongside chloramphenicol.

Levodopa, Methyldopa, Penicillamine: Iron may reduce the absorption of levodopa, methyldopa, and penicillamine when taken together. This could potentially interfere with the effectiveness of these medications.

Quinolones and Tetracyclines: The absorption of iron may be reduced when taken with quinolone antibiotics and tetracycline antibiotics. These antibiotics can form complexes with iron, decreasing its absorption.

Interaction That May Increase Iron Absorption:

• Vitamin C: Concurrent administration with vitamin C (ascorbic acid) can enhance the absorption of iron. Vitamin C can help convert non-heme iron (the type of iron found in plant-based foods and supplements) into a more absorbable form.

Contraindications

• Avoid concurrent use of both oral and parenteral (intravenous) iron therapy.
• Avoid using ferrous sulfate in individuals with iron-storage or iron-absorption diseases, such as hemochromatosis (a condition where the body absorbs too much iron).
• Avoid in individuals with hemoglobinopathies (genetic disorders affecting hemoglobin) as well as those with existing gastrointestinal (GI) diseases like inflammatory bowel disease, intestinal strictures, diverticula, peptic ulcer disease, enteritis, or ulcerative colitis.

Pregnancy & Lactation

The pregnancy category is not classified. The FDA has not classified the drug in a specific pregnancy category.

Precautions & Warnings

Iron Storage or Absorption Diseases (e.g., Hemochromatosis): In individuals with conditions like hemochromatosis, the body tends to accumulate excess iron. Administering iron supplements could exacerbate this issue, leading to further iron overload and related complications.

Hemoglobinopathy: Hemoglobinopathies are genetic disorders affecting hemoglobin (the protein in red blood cells that carries oxygen). These conditions, like sickle cell disease or thalassemia, can involve abnormal hemoglobin production and breakdown. The administration of iron in these cases must be carefully managed, as excessive iron intake can worsen the underlying condition.

Existing Gastrointestinal Diseases: Gastrointestinal (GI) diseases such as inflammatory bowel disease (IBD), intestinal strictures, diverticula, peptic ulcer disease, enteritis, or ulcerative colitis can impact the absorption and tolerance of iron supplements. These conditions may affect how well the body absorbs iron or cause discomfort when taking iron supplements.

Storage Conditions

Keep in a dry place at room temperature.