Onaseron 8 | Anti-nausea Medicine | 10pcs | Buy Now | ePharma
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Onaseron 8mg Tablet 10pcs

Generic: Ondansetron

Type: Tablet

Pack Size: 10 Pcs

Onaseron oral soluble film is designed to dissolve on the tongue within 20 seconds and can be swallowed with saliva, eliminating the need for water. The active ingredient is Onaseron base, a racemic form of Onaseron and a selective 5-HT3 receptor antagonist. Its empirical formula is C18H19N3O, with a molecular weight of 293.3.


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Discount Price: ৳ 103.4
MRP: ৳ 110 6% Off

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✅ Description:

Nausea is an uneasy stomach feeling that comes in waves and often precedes vomiting, where the body forcefully expels stomach contents through the mouth. Triggers include taste, anxiety, smell, pain, or stomach irritation. Cancer patients often experience nausea and vomiting after chemotherapy and radiation therapy. Controlling these symptoms is crucial for daily functioning, as unmanaged nausea and vomiting can lead to mental changes, loss of appetite, malnutrition, and dehydration.

Onaseron, a serotonin subtype 3 (5-HT3) receptor antagonist, is indicated for:

  • Preventing nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy.
  • Preventing and treating post-operative nausea and vomiting.
  • Preventing radiotherapy-induced nausea and vomiting.

Safety Advices


Alcohol
UNSAFE

avoid consuming alcohol while taking Onaseron 8 as this medicine can interact with alcohol and may worsen the side effects.


Pregnancy
CONSULT YOUR DOCTOR

Onaseron 8 is generally not recommended for use during pregnancy unless considered clearly necessary. Consult your doctor before taking Onaseron 8


Breastfeeding
CONSULT YOUR DOCTOR

Onaseron 8 is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking Onaseron 8.


Driving
CAUTION

Do not drive or operate any machines if you feel dizzy or uneasy after taking Onaseron 8.


CONSULT YOUR DOCTOR

Onaseron 8 tablets should be used with caution in patients with liver problems. Consult your doctor before taking Onaseron 8


Onaseron 8mg should be used with caution in patients with liver problems. Consult your doctor before taking Onaseron 8mg.

Similar Products

✔️ Uses of Onaseron 8
  • Used to manage nausea and vomiting induced by chemotherapy, radiotherapy, and surgery
✔️ How does Onaseron 8 work?

It  blocks a natural substance called serotonin in the brain that causes nausea and vomiting.

✔️ Side Effects of Onaseron 8
  • Constipation
  • Headache
  • Confusion
  • Dizziness
  • Fast heartbeat
  • Fever
  • Headache
  • Shortness of breath
  • Weakness
✔️ Quick Suggestions:
  • One should avoid taking greasy or oily foods as this food triggers nausea and vomiting.
  • Do not use Onaseron 8 with Apomorphine as it can cause a sudden fall in blood pressure leading to death or coma.
  • Onaseron 8 contains 'phenylalanine' so if you have Phenylketonuria (PKU) avoid its intake.
  • Eat cool foods instead of hot and spicy foods.
✔️ Pharmacology

Ondansetron is a potent and highly selective 5-HT3 receptor antagonist. Its precise mode of action in controlling nausea and vomiting is not fully known. Chemotherapeutic agents and radiotherapy can release 5-HT in the small intestine, initiating a vomiting reflex via 5-HT3 receptors on vagal afferents. Ondansetron blocks this reflex. The release of 5-HT in the area postrema (brainstem) may also contribute to emesis through a central mechanism. Thus, ondansetron likely manages nausea and vomiting by antagonizing 5-HT3 receptors in both the peripheral and central nervous systems. The mechanism for post-operative nausea and vomiting may involve similar pathways.

✔️ Dosage & Administration:

Chemotherapy-Induced Nausea and Vomiting:

  • Adults and Pediatric (6 months to 18 years):
    • Tablets/Oral Solution: Three 0.15 mg/kg doses, up to 16 mg per dose.
    • Injection: Three 0.15 mg/kg doses, up to 16 mg per dose, infused intravenously over 15 minutes.

Radiotherapy-Induced Nausea and Vomiting:

  • Adults:
    • Tablets/Oral Solution: 8 mg 1-2 hours before radiotherapy, then 8 mg every 8 hours for up to 5 days.

Postoperative Nausea and Vomiting:

  • Adults:
    • Tablets: 16 mg given as two 8 mg tablets.
    • Injection: 4 mg.
  • Pediatrics (>40 kg): Injection: 4 mg.
  • Pediatrics (<40 kg): Injection: 0.1 mg/kg.
✔️ Oral Soluble Film:
  • Highly emetogenic cancer chemotherapy: 24 mg (three 8 mg films) 30 minutes before chemotherapy.
  • Moderately emetogenic cancer chemotherapy:
    • Adults and pediatric (≥12 years): One 8 mg film 30 minutes before chemotherapy, then one 8 mg film 8 hours later, followed by 8 mg every 12 hours for 1-2 days.
    • Pediatric (4-11 years): One 4 mg film three times a day, starting 30 minutes before chemotherapy.
  • Radiotherapy-induced nausea and vomiting: One 8 mg film three times a day.
  • Postoperative nausea and vomiting: 16 mg (two 8 mg films) 1 hour before anesthesia.
✔️ Administration

To use the oral soluble film:

  1. Tear the pouch along the edge.
  2. Place the film on your tongue; it will dissolve within 20 seconds.
  3. Do not chew or swallow the film whole.
  4. Swallow after the film dissolves, with or without liquid.
  5. Wash your hands after handling the film.
✔️ Use in Special Populations
  • Renal impairment: No dosage adjustment is necessary.
  • Hepatic impairment: Maximum daily dose is 8 mg for severe impairment.
  • Children (≤4 years): Limited data available.
  • Elderly (>65 years): No dosage adjustment is needed.
✔️ Interaction

Onaseron does not appear to induce or inhibit the liver's cytochrome P-450 enzyme system. However, drugs that induce or inhibit these enzymes may alter Onaseron's clearance and half-life. No dosage adjustment is generally recommended for patients on such drugs.

✔️ Contraindications

Onaseron is contraindicated in patients with hypersensitivity to the drug or its components and in those taking apomorphine.

✔️ Pregnancy & Lactation

Animal studies have not shown evidence of harm to the fetus, but there are no adequate studies in pregnant women. Ondansetron is excreted in rat milk, so caution is advised when administering it to breastfeeding women.

✔️ Precautions & Warnings

Hypersensitivity reactions have been reported in patients sensitive to other 5-HT3 antagonists. Onaseron should not replace nasogastric suction in cases of gastric or intestinal peristalsis issues. It may mask progressive ileus or gastric distension post-abdominal surgery or chemotherapy-induced nausea and vomiting.

✔️ Storage Conditions

Store below 30ºC in a dry place, protected from light and moisture.

Frequently Asked Questions (FAQ)

No

A: The most common side effects of taking Onaseron 8 are headaches, flushing (feeling of warmth), constipation. Consult your doctor if above side effects got worse.

Onaseron 8 is an anti-nausea medicine that takes about 1-2 hours to show its action.
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Check our pricing section for Onaseron 8mg Tablet 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

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ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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