Omidon Suspension 60ml

Indications of Omidon 60ml

Omidon 60ml is a prescription medication that is used to treat indigestion, nausea, and vomiting. It inhibits the substance in the brain that causes nausea or vomiting, as well as increases the movement of food in the stomach, which improves digestion. Omidon 60ml  is taken before meals in the prescribed dose and duration.

Pharmacology

Domperidone is a dopamine antagonist that primarily blocks dopamine receptors in the chemoreceptor trigger Zone (CTZ) and stomach. Its gastroprokinetic activity is based on its ability to block dopamine receptors, which influence gastrointestinal motility. Omidon 60ml has almost no effect on the dopaminergic receptors within the brain due to its weak passage through the blood-brain barrier, barring psychotropic and neurologic side effects. Domperidone restores normal upper gastrointestinal motility and tone, promotes gastric purging, improves antral and duodenal peristalsis, and regulates pylorus compression. Domperidone also increases esophageal peristalsis and decreases esophageal sphincter weight, preventing the release of gastric contents.

Dosage & Administration of Omidon 60ml

Omidon 60ml tablet should be taken 15-30 minutes before meals and, if necessary, before retiring.

The usual recommended oral dose of Domperidone is as follows:

• Adults should take 10-20 mg (1-2 tablets or 10-20 mL suspension) every 6-8 hours. Domperidone's maximum daily dose is 80 mg.
• Children: every 6-8 hours, 2-4 mL suspension/10 kg body weight or 0.4-0.8 mL pediatric drops/10 kg body weight.
• Dyspeptic symptoms include:
• Adults should take 10-20 mg (1-2 tablets or 10-20 mL suspension) every 6-8 hours.
• Children: 0.2-0.4 mg/kg body weight (2-4 mL suspension/10 kg or 0.4-0.8 mL pediatric drops/10 kg) every 6-8 hours.

In acute and subacute conditions (especially acute nausea and vomiting):

• Adults should take 20 mg (2 tablets or 20 mL suspension) every 6-8 hours.
• Children: 0.2-0.4 mg/kg body weight (2-4 mL suspension/10 kg or 0.4-0.8 mL pediatric drops/10 kg) every 6-8 hours.  (In acute nausea and vomiting maximum period of treatment is 12 weeks).

By rectum in suppositories:

• Adults (including elderly): 30-60 mg every 4-8 hours.
• Children: The maximum daily dose rectally in children is 30 mg for those weighing 10 to 25 kg. The dose may be divided throughout the day if necessary.
• The maximum period of treatment is 12 weeks.

Interaction of Omidon 10

Domperidone may reduce the hypoprolactemic effect of bromocriptine. Domperidone's effect on Gl function may be mitigated by antimuscarinics and opioid analgesics. Domperidone should be used with caution when combined with MAO (monoamine oxidase) inhibitors.

Contraindications

Domperidone may reduce the hypo prolactin effect of bromocriptine. Domperidone's effect on Gl function may be mitigated by antimuscarinics and opioid analgesics. Domperidone should be used with caution when combined with MAO (monoamine oxidase) inhibitors.

Side Effects

Hyperprolactinemia is a side effect of domperidone (1.3 percent ). Galactorrhea, breast growth, discomfort, and a decrease in libido are all possible side effects. During domperidone treatment, dry mouth (1 percent), thirst, headache (1.2 percent), nervousness, drowsiness (0.4 percent), diarrhea (0.2 percent), skin rash, and itching (0.1 percent) are all possible side effects. Clinical investigations show that extrapyramidal responses occur in 0.05 percent of patients.

Pregnancy & Lactation

The security of domperidone has not been demonstrated and it is subsequently not prescribed during pregnancy. Creature considers have not illustrated the teratogenic impact on the baby. Omidon 60ml may accelerate galactorrhea and progress post-natal lactation. It is emitted in breast drain but in exceptionally little amounts inadequately to be considered hurtful.

Precautions & Warnings

Omidon 60ml ought to be utilized with supreme caution within the case of children since there may be an expanded chance of extrapyramidal responses in youthful children since of a not entirely created blood-brain boundary. Since domperidone is profoundly metabolized in the liver, it ought to be utilized with caution in persistent hepatic disability.

Storage Conditions

Do not store at temperatures above 30°C. Keep out of the reach of youngsters and away from light.