Generic Name: Lorazepam 1mg
Company Name: Incepta Pharmaceuticals Ltd.
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Indications
Lorazepam is used to treat anxiety states, including anxiety related to phobic and obsessional states, psychosomatic, natural, or insane illnesses, sleep deprivation related to anxiety, fear, eagerness, illness, and heaving related to chemotherapy and anticonvulsants, as well as as a premedical occasionally recently dental or common surgery or earlier to investigative methods where there may be distress. While lorazepam is not typically prescribed for anxiety states in children, it may be used as premedical care prior to surgery in children between the ages of 5 and 13 at doses of 0.05 mg/Kg. To avoid negative effects, the dose of the Lorazepam tablet should be increased gradually as needed. The evening measurements should be increased sometime after the daytime when the higher measurement is demonstrated.
Pharmacology
A benzodiazepine tranquilizer with quick action is lorazepam. In the central nervous system, it is an agonist of benzodiazepine receptors. It depresses the central nervous system, possibly by amplifying GABA's (gamma amino butyric acid) CNS-inhibitory effects. As a result, there will be a decrease in the ascending activating systems, especially the serotonergic and noradrenergic pathways from the brain stem or midbrain to the cerebral cortex.
Dosage & Administration
Interaction
When coupled with other central depressants, lorazepam has the potential to increase the central depressive effect. Alcohol, general anesthetics, tricyclic antidepressants, and monoamine oxidase inhibitors are examples of such medications.
Contraindications
Patients with a history of benzodiazepine sensitivity, acute narrow-angle glaucoma, or myasthenia gravis should not take lorazepam.
Side Effects
Typically, adverse reactions are observed at the beginning of treatment and almost always disappear as the medication is continued or the dosage is decreased. The sedation used after confusion, flaws, and shakiness is the most common negative visit reaction to lorazepam. Confusion, misery, nausea, altered craving, cerebral pain, sleep-unsettling influence, disturbance, dermatological symptoms, and eye-function-unsettling influence are less common negative reactions to visits, along with various gastrointestinal indications and autonomic manifestations.
Pregnancy & Lactation
Lorazepam's safety during pregnancy has yet to be determined. Lorazepam should nearly always be avoided during this era because its use is rarely necessary.
Oral Lorazepam, like other benzodiazepine tranquilizers, is not known to be eliminated in human milk. Nursing should not be done while a patient is on medication since many medicines are secreted in human milk.
Precautions & Warnings
Storage Conditions
Store at room temperature between 20°C to 25°C. Protect from moisture.
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