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Domar is a prescription medicine used in the treatment of indigestion, nausea, and vomiting.
Discount
Price: ৳ 39
MRP:
৳
40
3%
Off
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Cash on Delivery - All over Bangladesh
Regular Delivery - 8-12 Hours, Dhaka City*- Regular Delivery - 24-48 Hours, All Over Bangladesh*
✅ Description:
Indications of Domar Suspension
- Dyspeptic symptom complex
- Delayed stomach emptying
- Gastroesophageal reflux
- Esophagitis
- Upper abdominal pain
- The feeling of abdominal distension
- Epigastric fullness
- Early satiety
- Eructation
- Flatulence
- Vomiting and nausea
- Regurgitation of stomach contents into the mouth, with or without heartburn
- Dyspepsia without ulcers
- Acute nausea and vomiting of functional, organic, infectious, or dietetic origin
- Nausea and vomiting generated by radiotherapy or pharmacological therapy
- Nausea and vomiting induced in migraine
- Dopamine agonist-induced nausea and vomiting in Parkinson's disease
- Increasing the speed of barium transit in follow-up radiological tests
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✔️ Therapeutic Class:
- Motility Stimulants
- Motility stimulants/Dopamine antagonist
- Prokinetic drugs
✔️ Pharmacology:
- Domperidone: Dopamine agonist that blocks dopamine receptors in the ChemoreceptorTrigger Zone (CTZ) in the stomach.
- The gastroprokinetic function is based on inhibiting dopamine receptors in the gastrointestinal tract, affecting motility.
- Essentially no effect on dopaminergic receptors in the brain due to poor penetration across the blood-brain barrier.
- Restores normal upper gastrointestinal motility and tone.
- Aids stomach emptying, improves antral and duodenal peristalsis, and modulates pylorus contraction.
✔️ Dosage & Administration:
- Domperidone should be taken 15-30 minutes before meals and, if necessary, before retiring.
- Usual oral dose:
- Adults: 10-20 mg (1-2 tablets or 10-20 ml suspension), every 6-8 hours daily. Maximum dose: 80 mg daily.
- Children: 2-4 ml suspension/10 kg body weight or 0.4-0.8 ml pediatric drops/10 kg body weight, every 6-8 hours daily.
- In dyspeptic symptoms:
- Adults: 10-20 mg every 6-8 hours daily.
- Children: 0.2-0.4 mg/kg every 6-8 hours daily.
- In acute and sub-acute conditions:
- Adults: 20 mg every 6-8 hours daily.
- Children: 0.2-0.4 mg/kg every 6-8 hours daily. (Maximum treatment period: 12 weeks).
- By rectum in suppositories:
- Adults (including elderly): 30-60 mg every 4-8 hours.
- Children: Maximum daily dose rectally is 30 mg for those weighing 10 to 25 kg. The dose may be divided throughout the day if necessary.
✔️ Interaction:
- Bromocriptine's hypoprolactemic impact may be reduced by domperidone.
- Antimuscarinics and opioid analgesics may counteract Domperidone's effect on GI function.
- Caution is advised when used with MAO (monoamine oxidase) inhibitors.
✔️ Contraindications:
- Known hypersensitivity to domperidone.
- Neonates.
- Gastrointestinal stimulation potentially harmful conditions: gastrointestinal hemorrhage, mechanical obstruction, or perforation.
- Patients with a prolactin-releasing pituitary tumor (prolactinoma).
✔️ Side Effects:
- Hyperprolactinemia (1.3%)
- Galactorrhea, breast enlargement, soreness, reduced libido.
- Common: Dry mouth, thirst, headache, nervousness, drowsiness, diarrhea, skin rash, itching.
- Extra-pyramidal reactions were seen in 0.05% of patients in clinical studies.
✔️ Pregnancy & Lactation:
- Not recommended during pregnancy; safety not established.
- Can help with galactorrhea and postpartum lactation.
- Secreted in breast milk in small amounts, considered not dangerous.
✔️ Precautions & Warnings:
- Caution in children due to the risk of extrapyramidal effects.
- Caution in patients with hepatic impairment due to high metabolism in the liver.
✔️ Storage Conditions:
- Store at or below 30°C, away from light and moisture.
- Keep out of reach of youngsters.
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Please note that pricing, availability, and service offerings are subject to change due to: Market fluctuations, Manufacturer or supplier adjustments, Product discontinuation or temporary unavailability, Advertising errors. All orders depend on stock availability and staff resources. If services are provided on a time-and-materials basis, any shared estimates are for planning purposes only.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
