Laxicarbon is used in the management of diarrhoea and poisoning caused by contaminated food, heavy meals, and certain drugs. It is also effective in relieving flatulence resulting from dietary and other contributing factors.
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Laxicarbon, commonly known as activated charcoal, is a medicinal adsorbent used primarily in the treatment of oral poisoning. For optimal effectiveness, it should be administered as soon as possible, preferably within one hour of toxin ingestion. It is ineffective against poisoning caused by substances such as cyanide, corrosive agents, iron, lithium, alcohols, and malathion.
Activated charcoal may be administered orally or via a nasogastric tube. In specialized medical settings, it can also be used in hemoperfusion systems to remove toxins directly from the bloodstream.
Activated charcoal works by binding toxins and harmful substances within the gastrointestinal tract, thereby preventing their absorption into systemic circulation. In suspected poisoning cases, it is commonly administered at emergency sites or hospital emergency departments.
It also interrupts enterohepatic and enteroenteric circulation of certain drugs, toxins, and their metabolites, enhancing elimination from the body. Due to its effectiveness, activated charcoal has largely replaced older decontamination methods such as induced vomiting or gastric lavage, which are now rarely used.
Precise frequency of adverse effects cannot be determined due to post-marketing reporting. When used at recommended doses for diarrhoea, no significant adverse effects are known.
After very high doses, particularly in poisoning cases, the following may occur:
Constipation
Intestinal obstruction (mechanical ileus)
These effects can be prevented by administering saline laxatives (e.g., sodium sulfate).
Since activated charcoal is excreted unchanged, black discoloration of stools is a common and harmless finding.
Adults: 2–4 tablets, three to four times daily
Children: Half of the adult dose
Adults: 2–4 tablets per kg body weight
Children: 3–4 tablets per kg body weight
Adults: Dissolve 1–2 tablets; may be repeated every 2 hours if required
Laxicarbon (Ultracarbon) should not be taken simultaneously with other medications, as it may adsorb them and reduce their therapeutic effectiveness.
Febrile diarrhoea
Poisoning caused by corrosive substances such as strong acids or alkalis, as charcoal may interfere with essential diagnostic procedures (e.g., endoscopy)
No adequate clinical data are available regarding use during pregnancy or breastfeeding. Use only if clearly needed and under medical supervision.
Activated charcoal is ineffective against certain toxins, including organic/inorganic salts and solvents (e.g., lithium, iron salts, cyanide, methanol, ethanol, ethylene glycol). Alternative elimination methods such as gastric lavage, may be required.
In many poisonings, specific antidotes must be administered alongside charcoal (e.g., acetylcysteine for paracetamol overdose).
In unconscious patients, administration should be performed via gastric tube by a physician to prevent aspiration.
During repeated-dose therapy, intestinal motility should be monitored regularly.
Not recommended for poisoning caused by pesticides.
Store below 30°C in a dry place.
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