Type: Caps. Generic Name:Pregabalin INN 75mg & 150mg/capsule, Manufacturer/Distributor: Opsonin
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Pregaba is indicated for:
Pregaba CR tablet is indicated for:
Pregabalin, a structural derivative of gamma-aminobutyric acid (GABA), binds with high affinity to the alpha2-delta site of voltage-gated calcium channels in the central nervous system. Although its exact mechanism of action is not fully understood, animal studies suggest this binding may contribute to its pain-relieving and seizure-controlling effects.
Neuropathic pain associated with diabetic peripheral neuropathy in adults (DPN):
Postherpetic neuralgia in adults (PHN):
Fibromyalgia in adults:
Neuropathic pain associated with spinal cord injury in adults:
Conversion from Pregabalin capsules to Pregabalin CR tablets:
Pregabalin tablet to Pregabalin CR capsule dose conversion:
Pregabalin is taken orally, with or without food. Pregabalin CR tablets should be taken after an evening meal, swallowed whole, and not split, crushed, or chewed. If a dose is missed, it should be taken as soon as remembered with food, either before bedtime or with the next meal.
Drug Interactions: Pregaba is unlikely to be involved in significant pharmacokinetic drug interactions.
Contraindications: Pregabalin is contraindicated in patients with known hypersensitivity to Pregabalin or any of its components.
Common side effects in adults:
Common side effects in pediatric patients:
Symptoms of overdose include reduced consciousness, depression/anxiety, confusion, agitation, restlessness, seizures, and heart block. There is no specific antidote; supportive care, including monitoring of vital signs and clinical status, is recommended.
Store in a cool, dry place below 30°C, protected from light and moisture. Keep out of reach of children.
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