Generic Name: Calcium Lactate Gluconate 1000mg+ Calcium Carbonate 327mg+ Vitamin-C 500mg
Manufacturer: Incepta Pharmaceuticals Limited
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Indications
Hypercalcemia (as in hyperparathyroidism, vitamin D overdosage, decalcifying tumors like plasmacytoma, bone metastases); severe hypercalciuria; severe renal failure. Patients suffering from hypercalcemia, glucose-6-phosphate dehydrogenase deficiency, or iron overload. Larger doses may cause gastrointestinal upset.
Pharmacology
Calcium is almost entirely used as a pharmaceutical treatment for deficiency in humans. Calcium deficiency in the blood is so critical to a wide range of biological processes that our internal biochemistry will not tolerate even a temporary deficiency. Because man cannot produce vitamin C, it is a necessary component of the diet. It is a highly effective lowering agent. Vitamin C is essential for the body's stress response. It is critical in the battle
Dosage & Administration
Interaction
Calcium gluconate: A high-calcium diet combined with thiazide diuretics can result in milk-alkali syndrome and hypercalcemia. Digoxin toxicity may be increased. Calcium channel blockers should be used with caution. Calcitriol (a vitamin D metabolite) absorption is increased.
Calcium carbonate can cause milk-alkali syndrome and hypercalcemia when combined with thiazide diuretics or vitamin D. Corticosteroid absorption is reduced. Tetracycline, atenolol, iron, quinolones, alendronate, sodium fluoride, zinc fluoride, and calcium channel blockers are less absorbable. It will enhance the heart effect of digitalis glycosides and may lead to digitalis poisoning.
Vitamin C: Deferoxamine, hormonal contraceptives, fluphenazine, warfarin, elemental iron, salicylate, warfarin, fluphenazine, disulfiram, mexiletine, vitamin B12.
Contraindications
Severe hypercalciuria, hypercalcemia, and renal failure (e.g., hyperparathyroidism, vitamin-D overdosage, decalcifying tumors such as plasmacytoma, bone metastases). Patients with hyperoxaluria, glucose-6-phosphate dehydrogenase deficiency, and iron excess. Larger doses can cause stomach upset.
Side Effects
Mild gastrointestinal problems (bloating, diarrhea) might occur in rare situations. Long-term high-dose therapy in predisposed people may increase the development of calculi in the urinary system.
Pregnancy & Lactation
Oral calcium supplementation or antacid treatment with calcium-containing medications has been widely utilized in pregnancy. In lactating mothers, calcium carbonate can be used safely. Vitamin C can be consumed without risk during pregnancy and breastfeeding.
Precautions & Warnings
For patients with mild hypercalciuria (greater than 300mg=7.5mmol/24 hours), mild or moderate renal function impairment, or a history of urinary stones, it is necessary to monitor the excretion of calcium in the urine. If necessary, the dose should be reduced or treatment should be stopped. Unless otherwise specified, high doses of vitamin D and derivatives should be avoided during treatment with this preparation.
As citrate is reported to increase the absorption of aluminum, patients with severe renal insufficiency, especially those receiving aluminum-containing preparations, should use the drug with caution. Diabetes patients should pay attention to the sugar content.
Storage Conditions
Store in a cool, dry location away from light and moisture.
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