Nirvana 10mg Tablet

Uses of Nirvana 10mg Tablet

It is used to treat:

• Erectile Dysfunction
• Signs of Benign Prostatic Hyperplasia

How does Nirvana 10mg Tablet work?

Nirvana 10mg Tablet works by blocking the effects of certain enzymes (PDE5) in the body that limits blood flow to the penis. This relaxes the blood vessels supplying the penis, improves blood flow to the penis, and makes it stay erect throughout the process of sexual intercourse. It also relaxes the smooth muscles surrounding the bladder and prostate gland which improves the flow of urine thereby reducing the unpleasant signs of Benign Prostatic Hyperplasia.

Side Effects of Nirvana 10mg Tablet

• Headache
• Back pain
• Muscle pain
• Pain in legs and arms
• Nasal congestion
• Indigestion
• Facial flushing

Quick Suggestions:

• You have been prescribed Tadalafil for the treatment of erectile dysfunction.
• It is best to take it an hour before sexual intercourse. But, you can take it anytime between 30 minutes and 4 hours before sexual activity.
• Do not take it more than once a day.
• It may also be used for treating the urinary symptoms of an enlarged prostate gland (benign prostatic hyperplasia).
• It may cause dizziness or blurred vision. Do not drive or do anything requiring concentration until you know how it affects you.
• Avoid drinking alcohol as it can reduce your ability to get an erection and can make dizziness worse.
• Seek medical attention if the erection persists for more than 4 hours after sexual intercourse.
• Do not use Tadalafil if you have recently taken nitrates (medicines used in angina or chest pain), if you have had a heart attack in the past 3 months, or stroke or heart failure in the past 6 months.

Indication of Nirvana 10mg Tablet

Nirvana 10mg Tablet is used to treat erectile dysfunction, also known as impotence in men, which is the inability to achieve a satisfactory penile erection. It contains tadalafil as its active ingredient. Tadalafil works by increasing blood flow to the penis when combined with sexual stimulation, helping to achieve the desired erection. Take this medicine as prescribed by your doctor, and it can be taken with or without food.

Pharmacology

Tadalafil may be a specific phosphodiesterase sort 5 (PDE5) inhibitor. Restraint of PDE5 increments cGMP in smooth muscle cells. cGMP causes smooth muscle unwinding and expanded blood stream into the corpus cavernosum, causing penile erection. PDE5 moreover is shown in smooth muscles of the prostate and bladder divider. Restraining PDE5 increments cGMP concentrations leading to unwinding of smooth muscle within the prostate and bladder. Smooth muscle unwinding may progress the bloodstream to the urinary tract and extend the opening of the bladder neck, coming about in made strides voiding.

Dosage & Administration of Nirvana 10mg Tablet

Erectile Dysfunction: For most patients, the recommended starting dose is 10 mg. The dose may be increased to 20 mg or decreased to 5 mg based on the requirement. The maximum dosing frequency is once daily. Tadalafil is effective for up to 36 hours.

Benign prostatic hyperplasia: The recommended dose is 5 mg taken at the same time every day.

Combined Erectile Dysfunction and Benign prostatic hyperplasia: The recommended dose is 5 mg at the same time every day.

Interaction

Before taking Nirvana 10mg Tablet, inform your doctor if you are taking any of the following medicines:

1. Nitrates or amyl nitrites (used for relieving chest pain) Ex. nitroglycerin, isosorbide dinitrate
2. Other medicines used to treat erectile dysfunction (Ex. sildenafil)
3. Alpha-blockers (used to treat high blood pressure or benign prostatic hyperplasia) Ex. prazosin, terazosin, tamsulosin
4. Riociguat (a medicine used to treat increased pressure in the lungs)
5. Medicines used to treat BPH (Ex. dutasteride, finasteride)
6. Ketoconazole, itraconazole (used to treat fungal infection)
7. Protease inhibitors (used to treat HIV infection) Ex. ritonavir, lopinavir
8. Phenobarbital, phenytoin, carbamazepine (medicines used to treat fits)
9. Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)

Drug-Food Interactions: Avoid consuming grapefruit juice while taking Nirvana 10mg Tablet, as it may increase the risk of side effects.

Overdosage: If you or anyone else accidentally took more than Nirvana 10mg Tablet, consult your doctor or visit the nearby hospital.

Contraindications

• If you are allergic to tadalafil or any other ingredient present in Nirvana 10mg Tablet.
• If you are taking medicine known to cause vasodilator effects such as amyl nitrate or nitrates.
• If you are taking riociguat medicine used for the treatment of arterial blood pressure.
• If you have a known history of any heart problems such as heart failure.
• If you had a stroke in the past 6 months, heart attack in the last 90 days, or breathlessness or chest pain during sexual activity.
• If you have a known history of liver disorders, low blood pressure, stroke or heart blockage.
• If you have a known history of eye problems like retinitis pigmentosa (a genetic disorder that may cause loss of vision).
• If you are not sure if you are taking this medicine carry the medicine packet along with you to the clinic.

Pregnancy & Lactation

The USFDA has classified tadalafil as pregnancy category B. Tadalafil should only be used during pregnancy if the benefits exceed the risks. There is no information about Tadalafil excretion in human milk. When giving tadalafil to a nursing mother, exercise caution.

Precautions & Warnings

Angina, renal impairment, hepatic impairment, and bleeding when taking Nitrates, Alpha Blockers, Alcohol, CYP3A4 Inhibitors (such as Ritonavir, Ketoconazole, and Itraconazole), or other PDE5 inhibitors should all be avoided.

Storage Conditions

Keep away from light and heat in a dry location. Keep out of children's reach. Discard any unused, expired medicine properly. Do not flush the medicine.