Cream Urea 25%ww Ziska Pharmaceuticals Ltd.
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Indications
Adults & children over 12 years: It is intended to be used for the symptomatic treatment of heels & feet anhydrosis including in consumers and diabetics.
Pharmacology
Urea for external use has antibacterial, bactericidal, antibacterial, proteolytic, hygroscopic and mild local anesthetic properties. These effects are dose dependent. Most of its therapeutic applications depend on its hygroscopicity. Hygroscopicity is due to its ability to cause changes in the configuration of proteins in the stratum corneum. 10% urea cream has been shown to increase the water holding capacity of fish scales for 100 to 3 weeks after 3 weeks of treatment. There is no information on the percutaneous absorption of urea. The therapeutic effect depends on the local concentration, not the systemic absorption of the drug. If absorbed, urea will be excreted in the urine as it is.
Dosage & Administration
Apply enough Urea 25% Cream to cover affected area, once or twice daily or as directed by the physician. For external use only.
Interaction
No hazardous drug interaction has been reported.
Contraindications
Allergy to any of the ingredients of this product.
Side Effects
No serious toxicity has been reported with topical urea. Historically it is considered a safe drug. But on some occasions, topical urea has been shown to cause burning and irritation, if applied to inflamed, broken or exudative skin eruptions.
Pregnancy & Lactation
Urea cream can be used during pregnancy and lactation.
Precautions & Warnings
When applied to sensitive skin, urea 10% cream might cause local irritation and edema in certain cases. A doctor should be consulted if the condition becomes worse or does not improve. Avoid using this product on wet or damaged skin.
Storage Conditions
Keep out of the reach of children. Do not freeze. Keep at cool and dry place.
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here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
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