Perkinil 5mg Tablet | Parkinson’s disease | ePharma
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Perkinil 5mg Tablet 20pcs

Generic: Procyclidine Hydrochloride

Type: Tablet

Pack Size: 20pcs

Perkinil 5mg Tablet is a medication that belongs to the group of anticholinergics and is used to treat Parkinson's disease symptoms such as stiffness, tremors, and difficulty with movement. It is also used to control extrapyramidal symptoms caused by certain mental health medications that may cause restlessness and unusual head and body movements.

However, Perkinil 5mg Tablet should not be used in patients with tardive dyskinesia, which is a condition characterized by involuntary movements of the tongue or head. Patients with liver, kidney disease, high blood pressure, heart disease, glaucoma, or thyrotoxicosis should use Perkinil 5mg Tablet with caution, and pregnant women should only take it if absolutely necessary, after consulting their doctor. Breastfeeding mothers should also inform their doctor before taking Perkinil 5mg Tablet.

Perkinil 5mg Tablet is not recommended for use in children and adolescents, and elderly patients should use it with caution. Common side effects of Perkinil 5mg Tablet include dry mouth, blurred vision, constipation, and difficulty urinating. Patients should consult their doctor if any of these symptoms worsen.


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Description:

Perkinil is used for the adjunctive treatment of all forms of Parkinsonian syndrome. It is mainly used for the symptomatic treatment of idiopathic (paralysis agents), postencephalitic, and arteriosclerotic Parkinsonian. It is used to control troublesome extrapyramidal symptoms including pseudo parkinsonian, acute dystonic reactions, and akathisia induced by neuroleptic drugs such as phenothiazine derivatives.

Safety Advices


Alcohol
UNSAFE

Avoid consumption of alcohol while taking Perkinil 5mg Tablet as it may cause increased dizziness and drowsiness.


Pregnancy
CAUTION

Perkinil 5mg Tablet should be used during pregnancy only if it is considered clearly necessary. Consult your doctor before taking it.


Breastfeeding
CAUTION

It is unknown whether Perkinil 5mg Tablet passes into breastmilk. Consult your doctor before taking Perkinil 5mg Tablet if you are breastfeeding.


Driving
UNSAFE

Do not drive or operate any machines if you have blurred vision, dizziness, confusion, or disorientation after taking Perkinil 5mg Tablet.


Kidney

Perkinil 5mg Tablet should be used with caution in patients with kidney disease. Consult your doctor before taking it.


Liver
CAUTION

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns.

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Uses of Perkinil 5mg Tablet
  • To treat and relieve signs of Parkinson’s disease
  • To control extrapyramidal effects caused by certain medicines
How Perkinil 5mg Tablet works

Perkinil 5mg Tablet reduces the symptoms of Parkinson's disease, including muscle rigidity, sweating, and salivation, as well as improves walking ability in those who have the disease. It also helps to control Parkinson-like side effects brought on by some medications used to treat mental health conditions.

Side Effects of Perkinil 5mg Tablet
  • Dry mouth
  • Vomiting
  • Constipation
  • Nausea
  • Abdominal pain
  • Diarrhea
  • Fever
  • Decreased urination
  • Drowsiness
  • Feeling nervous or restless
  • Dizziness
  • Headache
  • Anxiety
  • Urinary retention
  • Sleepiness or unusual drowsiness
Quick Suggestions:
  • Perkinil 5mg Tablet helps treat Parkinson's disease and drug-induced abnormal movements.
  • A dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake, and sugarless candy may help.
  • Perkinil 5mg Tablet may cause dry eyes. Avoid wearing contact lenses and inform your doctor if it bothers you.
  • It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Inform your doctor if you suffer from glaucoma or if you have trouble passing urine.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Do not stop taking Perkinil 5 without talking to your doctor first as that may cause worsening of symptoms.
  • Monitoring of intraocular pressure is required while taking this medicine, as an increase in eye pressure may cause blurry vision.
  • You may be asked for regular monitoring of hypotension, kidney, liver, and cardiac disorder while taking this medicine.
Indication of Perkinil 5mg Tablet

Perkinil 5mg Tablet is used to treat symptoms of Parkinson's disease such as trembling, shakiness, stiff muscles or limbs, unusual head and body movements, etc. It is also used to treat side effects such as trembling, unusual body movements, Parkinson-like symptoms, etc. caused by other medicines.

Pharmacology

Perkinil (Procyclidine Hydrochloride) is a medication that belongs to the class of antimuscarinic antiparkinsonian agents. It has relatively low toxicity and is a synthetic tertiary amine. Its mechanism of action involves correcting the relative cholinergic excess that occurs in Parkinson's disease due to dopamine deficiency.

Perkinil is absorbed from the gastrointestinal tract and quickly disappears from the tissues. When given intravenously, it can take effect within 5 to 20 minutes and last for up to 4 hours.

Dosage & Administration of Perkinil 5mg Tablet

For adults, Perkinil 5mg Tablet is taken orally, preferably after meals. It is used to treat Parkinsonism and drug-induced extrapyramidal symptoms. The initial dosage for Parkinsonism is 2.5 mg three times a day, which may be increased to 5 mg three times a day and occasionally 5 mg at bedtime. The dosage can be adjusted as tolerated or until the total daily dose reaches 20 to 30 mg divided into 3 to 4 doses. For drug-induced extrapyramidal symptoms, the initial dosage is 2.5 mg three times a day, which can be increased by 2.5 mg per day as needed and tolerated. Injections can also be given, with a maximum of 20 mg daily.

However, the safety and effectiveness of Procyclidine Hydrochloride in children have not been established, and its use in this age group should only be considered after weighing the potential benefits against the possible risks.

Take Perkinil 5mg Tablet as advised by your physician. Take it with food to reduce nausea. Swallow the medicine with water. Do not crush or chew the medicine.

Your doctor will decide on an appropriate dose and duration depending on your age, body weight, and disease condition. Do not stop taking Perkinil 5mg Tablet unless your doctor advises you to stop. Otherwise, your symptoms may return.

Interaction

Perkinil 5mg Tablet may interact with certain medications such as antipsychotics, MAO inhibitors, antihistamines, anticholinergics, anti-convulsants, anti-depressants, anti-anxiety medications, and mild painkillers/fever-reducing agents. It is advised to avoid alcohol consumption as it may increase dizziness and drowsiness. The tablet may also interact with various medical conditions like irregular heartbeats, nerve damage, gastrointestinal obstruction, glaucoma, urinary obstruction, infectious diarrhea, involuntary facial movements, psychoses, high blood pressure, and fever.

Contraindications

Children and elderly patients should be used with caution. Patients with diarrhea and cardiovascular disease, glaucoma, urinary retention, and liver or kidney failure should be cautious when taking prostacyclin. The safety of using procyclidine during pregnancy has not been established. There are no data on the excretion of this drug in human milk.

Pregnancy & Lactation

The safe use of this drug in pregnancy, lactation, or in women of childbearing age requires that the potential benefits be weighed against the possible hazards to the mother and child.

Precautions & Warnings

If you have an allergy to any of the ingredients in Perkinil 5mg Tablet or narrow-angled glaucoma, do not take it. It is important to inform your doctor if you have glaucoma, prostate issues, problems with urination, stomach ulcers, acidity, myasthenia gravis (muscle weakness), tardive dyskinesia (involuntary facial movements), alcoholism, high blood pressure, or liver, kidney, or heart problems before taking Perkinil 5mg Tablet. If you experience hallucinations, contact your doctor immediately. Unless prescribed by a doctor, do not take Perkinil 5mg Tablet while pregnant or breastfeeding. Perkinil 5mg Tablet can cause drowsiness and dizziness, so do not drive if you feel sleepy. It is not recommended to give Perkinil 5mg Tablet to children due to a lack of safety and effectiveness data. Drinking alcohol with Perkinil 5mg Tablet could increase drowsiness and dizziness. Use good dental hygiene practices, such as brushing and flossing regularly, and visit the dentist frequently while taking Perkinil 5mg Tablet.

Storage Conditions

Protect from light and moisture, and store below 25°C. Keep out of the reach of children.

Frequently Asked Questions (FAQ)

In case of accidental overdose of Perkinil 5mg Tablet, seek medical attention immediately by contacting your doctor or going to the nearest hospital. Signs of an overdose may include rapid heartbeat, restlessness, agitation, confusion, severe insomnia, anxiety, aggressiveness, disorientation, unresponsiveness of pupils to light, hallucinations, extreme drowsiness, and even loss of consciousness or coma.

If you forget to take a dose of Perkinil 5mg Tablet, take it as soon as you remember. However, omit the missed dose if it's almost time for the next one. Do not take the medicine two times to make up for the missed dose.

Before taking Perkinil 5mg Tablet, inform your doctor if you are taking, have taken or might take any other medicine, including prescription, over the counter or any herbal medicine, as these might cause serious side effects by interacting with each other.

Take Perkinil 5mg Tablet as advised by your doctor. Generally, it is used for a period of 3 to 4 months of therapy and then your doctor may withdraw this medicine gradually to reduce the risk of extrapyramidal symptoms.

Perkinil 5mg Tablet should be used with caution during hot weather as it may increase the chance of having a heat stroke. Inform your doctor if you have heat intolerance or fever.

Try eating foods that encourage a bowel movement. Consult your doctor if you experience excessive constipation.

After an hour of starting Perkinil 5mg Tablet most people start experiencing the effects. However, the medicine may take some time for showing full benefits. Consult your doctor if you do not see improvement.

Antidepressants should be avoided while taking Perkinil 5mg Tablet as it might increase sedative effects. Consult your doctor before taking Perkinil 5mg Tablet if you are using depressants.
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Check our pricing section for Perkinil 5mg Tablet 20pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
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