Tablet. Generic Name: Rivaroxaban
Rivaroxaban 10-20 mg:
- To reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation
- Deep vein thrombosis (DVT) & pulmonary embolism (PE) and reduction in the risk of recurrence of DVT and of PE
- For the prophylaxis of DVT, which may lead to PE in patients undergoing knee or hip replacement surgery
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Description:
Dosage: The recommended dose is 2.5 mg twice daily. Patients should also take a daily dose of 75-100 mg Aspirin or a daily dose of 75-100 mg Aspirin in addition to either a daily dose of 75 mg clopidogrel or a standard daily dose of ticlopidine.
Nonvalvular Atrial Fibrillation: For patients with Creatinin Clearance >50 mL/min: 20 mg orally, once daily with the evening meal. For patients with Creatinin Clearance 15-50 ml/min: 15 mg orally, once daily with the evening meal.
Treatment of DVT & PE: 15 mg orally twice daily with food for the first 21 days for the initial treatment of acute DVT or PE. After the initial treatment period, 20 mg orally once daily with food for the remaining treatment.
Prevention in the risk of recurrence of DVT and of PE: 20 mg once daily with food
Prophylaxis of DVT following Hip replacement surgery: 10 mg once daily for 35 days
Prophylaxis of DVT following knee replacement surgery: 10 mg once daily for 12 days
Side effects: Nausea, vomiting, diarrhoea, constipation, dyspepsia, abdominal pain, dry mouth, hypotension, tachycardia, syncope, dizziness, headache, renal impairment, haemorrhage, pain in extremities, malaise, pruritus, rash, increases in liver enzyme values, thrombocythaemia, angioedema. Rarely, jaundice, oedema.
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