Flexibac 10mg 15pcs

Indications of Flexibac 10

Baclofen is used to treat skeletal muscle spasms caused by rheumatic disorders, spinal cord injuries, and other spinal diseases, as well as spasticity caused by multiple sclerosis, flexor spasms and pain, clonus, and muscular rigidity.
Cerebrovascular accidents, tumors, and degenerative brain disease are all possible causes.

Pharmacology of Flexibac 10

By stimulating GABAB receptors, which block glutamate and aspartate release, baclofen inhibits monosynaptic and polysynaptic reflexes in the spinal cord. Acting at intraspinal sites, it may also cause CNS depression. Baclofen also has an antinociceptive effect.

Administration & Dosage

• 5 mg three times a day, preferably with or after food, gradually increased to a maximum of 100 mg per day.

Interaction of Flexibac 10

• Baclofen may cause increased sedation when combined with central nervous system depressants, alcohol, or synthetic opiates. Respiratory depression is also a possibility.
• Because combining Baclofen with antihypertensives is likely to result in a greater drop in blood pressure, the antihypertensive medication dosage should be adjusted accordingly.

Contraindications

Baclofen is not recommended for patients who are hypersensitive to any of the product's ingredients.

Side Effect of Flexibac 10

Transient drowsiness, daytime sedation, dizziness, weakness, and fatigue are the most common side effects of baclofen. Headache (ten percent), insomnia (ten percent), euphoria, excitement, depression, confusion, hallucinations, paraesthesia, nightmares, muscle pain, tinnitus, slurred speech, coordination disorder, tremor, rigidity, dystonia, and ataxia are all symptoms of the central nervous system.

Pregnancy & Lactation

Baclofen is not safe to use during pregnancy, according to pregnancy category B3. Baclofen passes through the placental barrier. Baclofen should only be given to pregnant women if the physician believes that the potential benefits outweigh the potential risks. Baclofen is excreted in breast milk, but the evidence so far suggests that the amounts are so small that no adverse effects on the infant are expected.

Precautions & Warnings

• Lower doses should be administered to patients with impaired renal function or those undergoing chronic hemodialysis (approximately 5 mg per day).
• Spasticity patients, as well as those with psychotic disorders, schizophrenia, depressive or manic disorders, or confusional states, should be treated with caution and closely monitored, as these disorders can worsen.
• Notify your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.

Storage Conditions

Store below 30°C, away from light, in a cool, dry place. Keep out of children's reach.