Stener 300mg Tablet 10pcs

Uses of Stener 300

Treats primary biliary cirrhosis and gallbladder stones.

How does Stener 300mg Tablet work?

Suppresses hepatic synthesis and secretion of cholesterol and inhibits intestinal absorption of cholesterol.

Side Effects of Stener 300mg Tablet

Headache, dizziness, diarrhea, dyspepsia, nausea/vomiting, back pain, among others.

Quick Suggestions:

• Stener 300mg Tablet should be taken after a meal with a glass of milk or water.
• Eat a healthy diet, exercise regularly, and avoid alcohol intake.
• Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
• Your doctor may monitor your liver function and bilirubin levels every month for the next 3 months after the start of therapy, and every 6 months thereafter.
• Do not stop taking the medication without talking to your doctor.

Indications of Stener 300mg Tablet

Stener 300 is used to dissolve certain types of gallstones and to treat primary biliary cirrhosis, a liver disease. It helps break down cholesterol stones in the gallbladder.

Pharmacology

• Ursodeoxycholic Acid decreases the secretion of cholesterol in bile, reduces cholesterol absorption, and suppresses liver cholesterol synthesis.
• It alters bile composition from supersaturated to unsaturated and promotes the formation of liquid cholesterol crystal complexes, enhancing cholesterol removal from the gallbladder into the intestine.
• Ursodeoxycholic Acid protects cholangiocytes against cytotoxicity, stimulates hepatobiliary secretion, and protects hepatocytes against bile acid-induced apoptosis.
• It is completely absorbed in the upper intestine, enters the portal vein, undergoes extraction by the liver, conjugated with amino acids, and secreted into the hepatic bile ducts.

Dosage & Administration of Stener 300mg Tablet

Adult Dose:

• Oral Dissolution of Cholesterol-rich Gallstones: 8-12 mg/kg once daily or in 2 divided doses for 3-4 months.
• Primary Biliary Cirrhosis: 10-16 mg/kg daily in divided doses.

Take after a meal with milk or water. Swallow whole. The dosage depends on the condition being treated and body weight. Take regularly for several months or longer.

Interaction of Stener 300mg Tablet

Avoid concomitant administration with bile-acid binding drugs including antacids, charcoal, and cholestyramine, as this may reduce the effectiveness of Ursodeoxycholic Acid therapy.

Contraindications

Non-functioning gallbladder, calcified and pigmented gallstones, inflammatory bowel disease.

Pregnancy & Lactation

No evidence of harm has been reported in pregnancy. It has been effectively used for the treatment of cholestasis of pregnancy during the last trimester without any side effects.

Precautions & Warnings:

Avoid excessive dietary intake of calories and cholesterol. Monitor liver function tests and bilirubin levels.

Storage Conditions:

Store below 25°C. Protected from light and moisture. Keep out of the reach of children.