✔ 100% Authentic Product
Epleron 25mg Tablet 1 Strip
- Eplerenone is a selective aldosterone receptor antagonist that works by blocking aldosterone binding at the mineralocorticoid receptor.
- Aldosterone, a key component of the renin-angiotensin-aldosterone system (RAAS), plays a role in blood pressure regulation by promoting sodium retention and potassium excretion in the kidneys.
- Eplerenone prevents aldosterone from exerting its effects, leading to:
- Reduced sodium reabsorption
- Lower blood pressure
- Decreased fluid retention
- It has also been shown to increase plasma renin activity and aldosterone levels as a compensatory response, but these increases do not override its therapeutic effect.
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
Cashback offer (Optional):
🔹 Foreign manufacturer products are not applicable for Cashback offer
Cash on Delivery - All over Bangladesh
Urgent Delivery - 2 Hours Dhaka City
ফ্রি ডেলিভারি! - ১৪৯৯ টাকা+ অর্ডারে ঢাকা
শহরে ।- ফ্রি ডেলিভারি! - ২৯৯৯ টাকা+ অর্ডারে ঢাকার
বাহিরে ।
✅ Description:
Eplerenone
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Uses of Epleron 25
- Hypertension
✔️ Dosage & Administration of Epleron 25
For Congestive Heart Failure (Post-Myocardial Infarction):
- Initial dose: 25 mg once daily
- Target dose: 50 mg once daily (achieved within 4 weeks if tolerated)
- Can be taken with or without food
For Hypertension:
- Can be used alone or with other antihypertensive agents
- Starting dose: 50 mg once daily
- If blood pressure remains uncontrolled: Increase to 50 mg twice daily
- Higher doses (above 100 mg daily) are not recommended due to:
- Lack of additional blood pressure benefits
- Increased risk of hyperkalemia (high potassium levels)
Use in Special Populations:
- Pediatric patients: Safety and efficacy not established
- Geriatric patients: No significant differences in safety or effectiveness were observed
Note: This medication should be taken as per a physician’s recommendation.
✔️ Side Effects
Common side effects include:
- Headache, dizziness
- Gastrointestinal issues (diarrhea, stomach pain, nausea)
- Cough or flu-like symptoms
Serious allergic reactions (rare):
- Rash, itching, swelling
- Severe dizziness
- Difficulty breathing
✔️ Drug Interactions
- Increased risk of hyperkalemia when taken with:
- ACE inhibitors & angiotensin receptor blockers (ARBs)
- Ciclosporin, Tacrolimus, Trimethoprim
- Reduced antihypertensive effect when taken with:
- NSAIDs, glucocorticoids, tetracosactide
- Enhanced hypotensive (blood pressure-lowering) effect when taken with:
- Alpha-1 blockers (e.g., Alfuzosin, Prazosin)
- Tricyclic antidepressants (TCAs), Amifostine, Baclofen, Neuroleptics
- Increased plasma levels when taken with:
- Mild to moderate CYP3A4 inhibitors (e.g., Fluconazole, Erythromycin, Saquinavir, Amiodarone, Diltiazem, Verapamil)
✔️ Epleron should not be used in patients with:
- Hyperkalemia (high potassium levels)
- Severe renal impairment (Creatinine clearance <30 ml/min)
- Severe hepatic impairment
- Concomitant use with potent CYP3A4 inhibitors, such as:
- Ketoconazole, Itraconazole, Nefazodone, Troleandomycin, Clarithromycin, Ritonavir, Nelfinavir
- Use with other potassium-sparing diuretics
✔️ Pregnancy & Lactation
- Pregnancy:
- There are no well-controlled studies in pregnant women.
- Should only be used if the benefits outweigh the potential risks to the fetus.
- Lactation:
- It is unknown whether Eplerenone is excreted in human milk.
- A decision must be made to either discontinue breastfeeding or discontinue the drug, considering its importance to the mother.
✔️ Use with caution in patients with:
- Hyperkalemia
- Severe kidney disease
- Diabetic patients with CHF post-MI, especially those with proteinuria (protein in urine)
- Monitor potassium levels regularly to avoid complications.
✔️ Storage Conditions
- Store at temperatures below 30°C, in a cool and dry place.
- Keep away from light and moisture.
- Keep out of reach of children.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
