Adlock 40mg Tablet 10Pcs

✔️ Uses of Adlock 40mg Tablet

• Treatment of Arrhythmia
• Prevention of Heart attack
• Treatment of Pheochromocytoma
• Treatment of Hypertension (high blood pressure)
• Prevention of migraine
• Treatment of Anxiety
• Prevention of Angina (heart-related chest pain)
• Treatment of Tremors

✔️ Side effects of Adlock 40mg Tablet

• Arrhythmia (irregular heartbeats)
• Raynaud phenomenon
• Weakness
• Fingers and toes may become cold
• Sleep disturbances, nightmares
• Fatigue (tiredness)
• Swelling of face, lips, eyelids, tongue, hands and feet
• Irregular heartbeat
• Hypotension
• Chest pain and discomfort
• Signs of Raynaud’s syndrome (numbness and spasm in the fingers followed by warmth and pain)

✔️ How Adlock 40mg Tablet works

Adlock 40mg is a beta-blocker that blocks the actions of certain chemical messengers in the body that control the function of the heart, brain, kidneys, and lungs. It works by reducing the heart rate and force of contraction, improving blood flow and oxygen supply to the heart and brain, treating and preventing problems caused by poor blood circulation, reducing the production of thyroid hormones in patients with overactive thyroid glands, and reducing tremors by stopping the transfer of abnormal nerve signals between the brain and muscles.

✔️ Quick Suggestions:

• Adlock 40mg Tablet is not the first-choice treatment for high blood pressure according to the latest guidelines.
• It may hide the symptoms of low blood sugar if you have diabetes. Monitor blood sugar levels regularly.
• To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
• Use caution while driving or doing anything that requires concentration as Adlock 40mg Tablet can cause dizziness and sleepiness.
• Inform your doctor if you notice increased swelling around your legs or ankles, sudden weight gain, or sudden shortness of breath as these may be symptoms of heart failure.
• Do not stop taking the medication suddenly without talking to your doctor.

✔️ Indication of Adlock 40mg Tablet

Propranolol Hydrochloride is a medication used to treat hypertension, arrhythmia, and angina, and to improve survival after a heart attack. It works by blocking the effects of certain chemical messengers in the body, which in turn slows the heart rate and relaxes the blood vessels. This helps to reduce high blood pressure and improve blood flow to the heart. Additionally, propranolol is used to treat phaeochromocytoma, tremors, hypertrophic subaortic stenosis, and migraine headaches. It is available in various forms including tablets, capsules, sustained-release tablets/capsules, extended-release capsules, and injections.

✔️ Pharmacology

Propranolol is a non-cardioselective beta-blocker that competitively blocks beta1- and beta2-receptors resulting in decreased heart rate, myocardial contractility, BP, and myocardial oxygen demand. It has membrane-stabilizing properties.

✔️ Dosage & Administration of Adlock 40mg Tablet

This medication can be taken orally and is used to treat various conditions. 

Adult Dose:

• For hypertension, the initial dose for adults is 40-80 mg twice a day and the usual range is 160-320 mg per day, with a maximum of 640 mg per day.
• For phaeochromocytoma, the recommended dose for adults is 60 mg per day in divided doses given three days before surgery with an alpha-blocker.
• For myocardial infarction, the usual range is 180-240 mg per day in divided doses within 5-21 days of the event.
• For cardiac arrhythmias, the recommended dose is 30-160 mg per day in divided doses.
• For prophylaxis of migraine, the initial dose is 40 mg twice or three times a day, with a usual range of 120-240 mg per day.
• For portal hypertension, the initial dose is 40 mg twice a day and can be increased up to 160 mg twice a day.
• For angina pectoris, the usual range is 120-240 mg per day, with a maximum of 320 mg per day.
• For hypertrophic cardiomyopathy, the recommended dose is 10-40 mg, 3-4 times daily.
• For hyperthyroidism, the usual range is 10-40 mg, 3-4 times daily, or 80 mg once daily with a maximum of 240 mg per day.
• For anxiety, the recommended dose is 10-40 mg twice or three times a day, or 80 mg once daily with a maximum of 160 mg per day.
• For essential tremors, the usual range is 120-240 mg per day, with a maximum of 240 mg per day.
• The extended-release capsule should be taken at an initial dose of 80 mg once daily, with a usual range of 120-160 mg once daily and a maximum of 640 mg per day.

Child Dose:

• The dose for children varies depending on the condition being treated and the child's weight, but generally, the dose is lower than for adults.

Administration

Take Adlock 40mg Tablet as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Try to take Adlock 40mg Tablet at the same time each day. It is preferable to be taken before meals.

Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and health condition. Do not stop taking Adlock 40mg Tablet unless advised by your doctor.

✔️ Interaction

Propranolol hydrochloride may have additive negative effects on heart rate and heart muscle function when used in combination with drugs such as amiodarone, disopyramide, quinidine, flecainide, and calcium channel blockers. When used with phenothiazines, it may cause additive hypotensive effects. The β-adrenergic stimulating effects of sympathomimetic agents are antagonized by propranolol hydrochloride. The concurrent use of catecholamine-depleting drugs (e.g. reserpine) may cause additive effects and potentiate depression.

The antihypertensive effect of propranolol hydrochloride may be reduced when used in combination with aluminum and nonsteroidal anti-inflammatory drugs (NSAIDs). When co-administered with warfarin, the bioavailability and prothrombin time of warfarin may be increased. The antidiabetic response may be altered when propranolol hydrochloride is used with antidiabetic agents and insulin. When used with anesthetics, there is an increased risk of hypotension and attenuation of the reflex tachycardia.

Concurrent use of thioridazine with propranolol hydrochloride may increase the risk of QT interval prolongation and torsades de pointes, which can be potentially fatal. Therefore, caution is advised when using propranolol hydrochloride with these drugs, and close monitoring is necessary.

✔️ Contraindications

Propranolol hydrochloride should not be used in patients with sinus bradycardia, cardiogenic shock, sick sinus syndrome, 2nd and 3rd-degree heart block, or overt congestive heart failure (CHF). It should also be avoided in patients with bronchial asthma, chronic obstructive pulmonary disease (COPD), untreated phaeochromocytoma, Prinzmetal's angina, severe peripheral arterial disease, metabolic acidosis, or Raynaud's syndrome.

Additionally, concomitant use of thioridazine should be avoided due to the risk of serious adverse effects, including hypotension, bradycardia, and cardiac arrest.

It is important to inform your doctor if you have any of these conditions before taking propranolol hydrochloride. Also, do not stop taking propranolol hydrochloride abruptly without consulting your doctor, as this can lead to changes in heart rhythm and blood pressure. Your doctor will gradually reduce your dose to prevent these symptoms. Regular monitoring of prothrombin time is also necessary if propranolol hydrochloride is taken with anticoagulants like warfarin.

✔️ Pregnancy & Lactation

Pregnancy category: C, D in 2nd & 3rd trimesters.

✔️ Precautions & Warnings

• Adlock 40mg Tablet is not recommended for use in individuals with cardiogenic shock or heart failure.
• If you need to stop taking Adlock 40mg Tablet, you should consult with your doctor first as abruptly stopping the medication may result in changes in heart rhythm and blood pressure.
• Your doctor will gradually reduce your dosage over time to avoid such symptoms.
• You should not take Adlock 40mg Tablet if you have a very slow heart rate, asthma, sick sinus syndrome, or any heart blockage.
• Before taking Propranolol Hydrochloride, inform your doctor if you have any muscle disorder such as myasthenia gravis or rhabdomyolysis, breathing problems such as COPD, bronchitis, or emphysema, low blood sugar levels (hypoglycemia), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder, adrenal gland cancer, or circulation problems such as Raynaud's syndrome.
• Taking Adlock 40mg Tablet may mask the symptoms of diabetes, so inform your doctor if you have type 1 or type 2 diabetes. Furthermore, it may exacerbate symptoms of congestive heart failure and bradycardia (slow heart rate of less than 60).
• If you take Propranolol Hydrochloride with anti-coagulants such as warfarin, you should monitor your prothrombin time regularly.

✔️ Storage Conditions

Store in a cool and dry place away from sunlight