Helicobacter pylori eradication (in combination with antibiotics) Syndrome of Zollinger-Ellison
A proton pump inhibitor, pantoprazole binds covalently to the H+/K+ ATPase enzyme system on the surface of the gastric parietal cell to reduce the last stage of stomach acid generation. Regardless of the stimulus that lasts longer than 24 hours, this impact results in a suppression of both basal and induced stomach acid secretion.
Dosage & Administration
Duodenal ulcer and gastric ulcer: 40 mg once daily for 7-10 days
Gastroesophageal reflux disease associated with a history of erosive esophagitis: 40 mg once daily for 7-10 days
Prevention of rebreeding in peptic ulcer: IV 80 mg, followed by 8 mg/hour infusion for 72 hours
Prophylaxis of acid aspiration: 80 mg IV every 12 h for 24 h, followed by 40mg every 12 hour
Long-term management of Zollinger-Ellison Syndrome and other pathological hypersecretory conditions: 80 mg IV every 12 hours, may increase to 80 mg every 8 hours if needed, may titrate to higher doses depending on the acid output.
Direction for use of IV injection:
Pantoprazole lyophilized powder and 0.9% Sodium Chloride Injection are for intravenous administration only and must not be given by any other route. Pantoprazole IV injection should be given as a slow intravenous injection. The solution for IV injection is obtained by adding 10 ml 0.9% Sodium Chloride Injection to the vial containing powder. After reconstitution, the injection should be given slowly over a period of at least 2 to 5 minutes. Use only freshly prepared solutions. The reconstituted solution may be stored at room temperature (up to 30° C) for a maximum of 4 hours.
How to use Pantonix Injection:
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
How Pantonix Injection works:
Pantonix 40mg Injection is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which in turn relieves acid-related indigestion and heartburn.
No significant drug interactions have been observed in clinical studies.
Pantoprazole is contraindicated in patients with known hypersensitivity to any of the components of the formulation.
Side Effects of Pantonix Injection
Pantoprazole is well tolerated in both short-term and long-term treatment. Headache and diarrhea are the common side effects and rarely included side effects are abdominal pain, flatulence, rash, insomnia, and hyperglycemia.
Pregnancy & Lactation
US FDA Pregnancy Category of Pantoprazole is B. There are, however, no adequate and well-controlled studies on pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Pantoprazole has been shown to be excreted in human milk. So, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the benefit of the drug to the mother.
Precautions & Warnings
Patients should be cautioned that Pantoprazole tablets should not be split, chewed, or crushed. Long-term therapy of Pantoprazole may lead to malabsorption of cyanocobalamin (Vitamin B12) or may increase the risk of osteoporosis-related disorders.
There are no known symptoms of overdosage in humans. Since Pantoprazole is highly protein-bound, it is not readily dialyzable. Apart from symptomatic and supportive management, no specific therapy is recommended.
Keep in a dry place, away from light and heat. Keep out of the reach of children. anesthesia
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Pantonix 40mg 98Pcs (Box)
Pantonix 20mg (Box)
Pantonix 40mg 14pcs
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