Famotack 20mg Tablet

✔️ Uses of Famotack 20mg Tablet

• Treatment of Gastroesophageal reflux disease (Acid reflux)
• Treatment of Peptic ulcer disease
• Treatment of Heartburn

✔️ How does Famotack 20mg Tablet work?

Famotack 20mg Tablet effectively heals stomach ulcers by blocking certain receptors called Histamine (H2) receptors which are present in the stomach walls which in turn reduces the production of gastric acid and decreases the volume of gastric secretion in the stomach.

✔️ Side Effects of Famotack 20mg Tablet

• Diarrhea
• Dizziness
• Headache
• Hypertension
• Fever
• Fatigue
• Seizures
• Insomnia
• Drowsiness
• Acne
• Pruritus
• Urticaria
• Dry Skin
• Abdominal Discomfort
• Flatulence
• Belching
• Anorexia
• Weakness
• Thrombocytopenia
• Bronchospasm
• Allergic Reaction

✔️ Quick Suggestions:

• Famotack 20mg Tablet is a well-tolerated and safe medicine with a very low incidence of side effects.
• Take it with or without food.
• If you are also taking other medications to treat acidity (e.g., antacid), take them 2 hours before or after taking Famotack 20.
• Avoid taking soft drinks, and citrus fruits like oranges and lemons, which can irritate the stomach and increase acid secretion.
• Inform your doctor if you do not feel better after taking Famotack 20 for 2 weeks as you may be suffering from some other problems.
• Inform your doctor if you have ever been diagnosed with kidney disease as a dose of your medicine may need to be adjusted.
• Do not stop taking the medication without talking to your doctor.

✔️ Indication of Famotack 20mg Tablet

Famotack 20mg Tablet is used to treat:

• Stomach ulcers (gastric or duodenal ulcers)
• Reflux oesophagitis
• Zollinger−Ellison syndrome (recurrent ulcers and tumors in the stomach and intestines)

✔️ Pharmacology

Famotidine is a medication that belongs to the class of histamine H2-receptor antagonists. It works by blocking the action of histamine on H2-receptors found in the parietal cells in the stomach. By doing so, famotidine effectively inhibits the secretion of gastric acid, including both the basal (normal) acid secretion, as well as the acid secretion stimulated by overnight fasting or by the hormone pentagastrin.

One important characteristic of famotidine is its slow reversibility as an H2-receptor antagonist. This means that once famotidine binds to the H2-receptor, it remains bound for an extended period of time before eventually dissociating from the receptor. This slow dissociation contributes to the prolonged and sustained effect of famotidine in inhibiting gastric acid secretion.

Overall, famotidine's mechanism of action involves blocking the histamine-mediated stimulation of gastric acid secretion by competitively binding to the H2-receptors on parietal cells and preventing the action of histamine.

✔️ Dosage & Administration of Famotack 20mg Tablet

Here are the recommended dosages for different conditions when using famotidine:

• Duodenal ulcer: The typical dosage is 40 mg taken at night for a period of 4 to 8 weeks.
• Benign gastric ulcer: The usual dosage is 40 mg taken at night for 4 to 8 weeks. After the initial treatment, a maintenance therapy dose of 20 mg taken at night can be used to prevent the recurrence of duodenal ulceration.
• Gastro-oesophageal reflux disease (GERD): The recommended dosage is 20 mg taken twice daily for a duration of 6 to 12 weeks.
• Zollinger Ellison syndrome: The starting dose is usually 20 mg taken every six hours. The dosage may be adjusted based on the individual response, and some patients may require doses up to 160 mg every six hours. It's important to note that these high doses should only be taken under medical supervision.

Famotidine can be taken with or without meals, as it is not affected by food. If necessary, antacids can be taken concurrently with famotidine.

It's important to follow the prescribed dosage instructions provided by your healthcare provider and to consult them if you have any questions or concerns about your specific dosage regimen.

✔️ Interaction

Antacids may slightly decrease the bioavailability of famotidine, which means it may reduce the amount of famotidine that is absorbed into the bloodstream. This interaction is not considered significant and usually does not require any dose adjustments.

Additionally, famotidine may potentially reduce the serum concentration of ketoconazole and itraconazole, which are medications used to treat fungal infections. This is because famotidine can increase gastric pH, which may affect the absorption of these antifungal drugs. It is advisable to monitor the therapeutic effects of ketoconazole or itraconazole if they are taken concomitantly with famotidine and adjust the dosage if necessary.

It's important to inform your healthcare provider about all the medications you are taking, including over-the-counter drugs, herbal supplements, and any other prescription medications. They can provide you with personalized advice and guidance regarding potential drug interactions.

✔️ Contraindications

There are no known contraindications to Famotidine. If any evidence of hypersensitivity appears, the therapy should be discontinued and consultation with a physician is required.

✔️ Pregnancy & Lactation

Pregnancy: There are no adequate, well-controlled studies on Famotidine in pregnancy, but it is known to cross the placenta and should be prescribed only if clearly needed.

Lactation: It is not known whether Famotidine is secreted into human milk, nursing mothers should either stop nursing or stop taking the drug.

✔️ Precautions & Warnings

• In cases of impaired renal function, caution should be exercised when using famotidine. The dose may need to be adjusted based on the severity of renal impairment. It is recommended to consult a healthcare professional for appropriate dosage recommendations in such cases.
• Regarding long-term treatment, it is generally advised to avoid prolonged use of famotidine unless specifically directed by a healthcare professional. This is because long-term use may increase the risk of certain side effects or complications. It is important to follow the prescribed treatment duration and consult your doctor for further guidance.
• Famotidine enters breast milk, and its use is not recommended during lactation. There is a potential risk of the drug being passed to the nursing infant through breast milk. It is advisable to discuss alternative options with a healthcare provider if you are breastfeeding or planning to breastfeed while taking famotidine.

✔️ Storage Conditions

Store between 15-30° C.