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Indications of Ace Power
Paracetamol is suitable for fever, common cold and flu, headache, toothache, earache, body pain, myalgia, neuralgia, dysmenorrhea, sprain, colic, back pain, postoperative pain, postpartum pain, inflammatory pain and pain in children after vaccination. It is also suitable for rheumatic pain and osteoarthritis and joint stiffness.
Pharmacology
Paracetamol has analgesic and antipyretic properties, and its anti-inflammatory activity is weak. Paracetamol (acetaminophen) is believed to act mainly on the central nervous system, increasing the pain threshold by inhibiting two isoforms of cyclooxygenase COX1, COX2 and COX3, which are involved in the synthesis of prostaglandin (PG). Paracetamol is a derivative of p-aminophenol, has analgesic and antipyretic effects, and has weak anti-inflammatory activity. Paracetamol is one of the most widely used, safest, and quick-acting analgesics. It is well tolerated and does not have various aspirin side effects.
Dosage & Administration
Tablet:
Adult: 1-2 tablets every 4 to 6 hours up to a maximum of 4 gm (8 tablets) daily.
Children (6-12 years): ½ to 1 tablet 3 to 4 times daily. For long term treatment it is wise not to exceed the dose beyond 2.6 gm/day.
Extended Release Tablet:
Adults & Children over 12 years: Two tablets, swallowed whole, every 6 to 8 hours (maximum of 6 tablets in any 24 hours).The tablet must not be crushed.
Side Effect
Thrombocytopenia, leucopenia, pancytopenia, neutropenia, agranulocytosis, pain and burning sensation at inj site. Rarely, hypotension and tachycardia. Potentially Fatal: Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalised exanthematous pustulosis, acute renal tubular necrosis and hepatotoxicity.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.