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Home Medicines Epilepsy Oxcarb XR 300 | 1 Strip

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Oxcarb XR 300 | 1 Strip

Name: Oxcarb XR 300 | 1 Strip
Brand: Renata Limited
SKU: 7150
Price: 102 BDT
Availability: InStock
Rating: 4.8 (86 reviews)

Renata Limited

Generic: Oxcarbazepine

Type: Tablet

Pack Size: 6 Pcs

Tablet

6 Pcs

৳ 108 ৳ 106

Used to manage epilepsy by reducing seizures

📄Prescription Required

Discount Price: ৳ 106

MRP: ৳ 108 2% Off

🎉 Save ৳: 2 in this Product

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Regular Delivery - 12-24 Hours, Dhaka City* Charge Tk.39-59
Regular Delivery - 24-48 Hours, Other Cities* Charge Tk.99-110

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✅ Description:

The therapeutic activity of Oxcarbazepine is mainly due to its 10-monohydroxy metabolite (MHD).

Mechanism of action:

Blocks voltage-sensitive sodium channels, stabilizing hyperexcited neuronal membranes.
Suppresses repetitive neuronal firing.
Reduces propagation of synaptic impulses.
Additional effects:
Enhances potassium conductance.
Modulates high-voltage-activated calcium channels.

These combined actions contribute to its anticonvulsant effect.

No significant interaction with major brain neurotransmitter receptor sites has been demonstrated.

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✔️ Uses

Adults: Monotherapy or adjunctive therapy for the treatment of partial seizures.

Pediatrics:

Monotherapy in children 4–16 years with partial seizures.

Adjunctive therapy in children 2–16 years with partial seizures.

✔️ Dosage & Administration

Adults:

Initial: 600 mg/day in two divided doses.

Adjunctive therapy: Increase by 600 mg/day at weekly intervals; recommended dose: 1200 mg/day.

Conversion to monotherapy: Withdraw other AEDs over 3–6 weeks; titrate Oxcarb XR to 2400 mg/day in 2–4 weeks.

Initiation of monotherapy: Increase by 300 mg/day every 3rd day to 1200 mg/day.

Renal impairment (CrCl <30 mL/min): Start with half the usual dose, titrate cautiously.

Pediatrics:

Starting dose: 8–10 mg/kg/day in two divided doses.

Children 2–<4 years and <20 kg: May start with 16–20 mg/kg/day.

Maintenance: Should not exceed 60 mg/kg/day.

Adjunctive therapy (2–16 years):

Age 4–16: Achieve target maintenance dose in 2 weeks.

Age 2–<4: Achieve maximum dose in 2–4 weeks.

Conversion to monotherapy (4–16 years): Increase by 10 mg/kg/day weekly, taper other AEDs over 3–6 weeks.

Initiation of monotherapy (4–16 years): Increase by 5 mg/kg/day every 3rd day.

Dosage must be individualized under physician supervision.

✔️ Side Effects

CNS: Dizziness, diplopia, headache, nystagmus, abnormal gait.

GI: Nausea, vomiting, abdominal pain.

Dermatologic: Rash.

Serum electrolytes: Hyponatremia (monitor sodium levels).

Rare: Bone marrow

✔️ Interaction

Minimal interaction with cytochrome P450 enzymes.

No significant interactions observed with cimetidine, dextropropoxyphene, erythromycin, or warfarin.

Caution with other antiepileptics due to possible pharmacokinetic interactions.

✔️ Contraindications

Known hypersensitivity to Oxcarbazepine, its components, or eslicarbazepine acetate.

✔️ Pregnancy & Lactation

Pregnancy: Category C – use only if benefits outweigh risks.

Lactation: Excreted in breast milk (milk-to-plasma ratio ~0.5); not recommended during breastfeeding.

✔️ Precautions & Warnings

Risk of cognitive/neuropsychiatric effects: psychomotor slowing, concentration/language problems, somnolence, fatigue, ataxia, gait disturbance.

Hyponatremia: May occur; monitor serum sodium, especially if the patient is on sodium-lowering drugs.

Use cautiously in patients with carbamazepine hypersensitivity (cross-reactivity possible).

✔️ Storage:

Store below 30°C, in a dry place, protected from light and moisture.

Frequently Asked Questions (FAQ)

+ Q. What is Oxcarb XR 300 Tablet used for?

A: Oxcarb XR 300 is prescribed for the management of epilepsy by reducing seizures. It may also be used off-label for neuropathic pain.

+ Q. Does Oxcarb XR 300 cause drowsiness or affect driving?

A: Yes. Drowsiness, dizziness, or blurred vision may occur. Avoid driving or operating machinery until you know how the medicine affects you.

+ Q. What are the common side effects of Oxcarb XR 300?

A: Drowsiness, dizziness, headache, blurred vision, low sodium levels (causing weakness or confusion), and nausea.

+ Q. Is Oxcarb XR 300 safe during pregnancy or breastfeeding?

A: Oxcarb XR 300 belongs to Pregnancy Category C. It should only be used if the benefit outweighs the risks. It may pass into breast milk, so consult your doctor before use.

+ Q. Does Oxcarb XR 300 interact with oral contraceptives?

A: Yes. Oxcarb XR 300 may reduce the effectiveness of hormonal contraceptives. Use non-hormonal or additional contraceptive methods as advised by your doctor.

+ Q. Does Oxcarb XR 300 cause weight gain?

A: Weight gain is not common, but effects may vary from person to person.

+ Q. Is Oxcarb XR 300 safe for long-term use?

A: Yes, but long-term treatment requires regular medical check-ups to monitor for side effects.

+ Q. Can Oxcarb XR 300 Tablet be given to children?

A: Yes, Oxcarb XR 300mg may be used in children with epilepsy, but only under the strict supervision of a doctor.

+ Q. What is the usual dosage for Oxcarb XR 300?

A: Epilepsy (adults): Start with 300 mg twice daily (600 mg/day). Increase by 600 mg weekly if needed. Maintenance: 600–2400 mg/day in 2 doses. Neuropathic pain (off-label): Start with 300 mg once or twice daily, increase gradually. Usual dose: 900–1800 mg/day (max 2100 mg/day if tolerated).

+ Q. Is Oxcarb XR 300 safe for patients with liver problems?

A: Use with caution. In severe liver disease, your doctor may adjust the dose.

+ Q. How does Oxcarb XR 300mg work?

A: Oxcarb XR 300 stabilizes electrical activity in the brain by blocking sodium channels, helping to reduce abnormal nerve impulses that cause seizures. Q:

+ Q. How should I take Oxcarb XR 300 Tablet?

A: Swallow the tablet whole with water. Do not crush or chew. Take it once or twice daily, with or without food, as prescribed.

+ Q. How long does it take for Oxcarb XR 300 to work?

A: It usually starts working within hours, but full seizure control may take a few weeks of regular use.

+ Q. Can I stop taking Oxcarb XR 300 suddenly?

A: No. Stopping suddenly may trigger seizures or withdrawal effects. Your doctor will guide you on how to taper the dose safely.

+ Q. What if I miss a dose of Oxcarb XR 300?

A: Take it as soon as you remember, unless it’s nearly time for your next dose. Do not double the dose.

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⚠️Disclaimer:

At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

📦Pricing Information, Availability:

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