Aromatin 1mg Tablet

Uses of Aromatin 1mg Tablet

• Treats breast cancer in postmenopausal women

How does Aromatin 1mg Tablet work?

Aromatin 1mg Tablet is an effective treatment for breast cancer as it works by reducing the levels of the hormone estrogen. It specifically targets areas in the body, such as muscles, breast tissue, and fatty tissue, where the enzyme aromatase is present. Aromatase plays a role in the production of estrogen. By inhibiting the action of aromatase, Aromatin 1mg Tablet effectively decreases the synthesis of estrogen, thereby helping to treat breast cancer.

Side Effects of Aromatin 1mg Tablet

• Dizziness
• Headache
• Vaginal bleeding
• Hair thinning
• Change in mood
• Hot flashes
• Loss of appetite
• Weight gain
• Joint pain
• Sore throat
• Nausea
• Stomach pain
• Tiredness and weakness
• Drowsiness

Quick Suggestions:

• Aromatin 1 is used for the treatment of hormone-dependent breast cancer in postmenopausal women.
• Take it at the same time every day.
• Maintain a healthy diet: Consume a balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats. Include leafy green vegetables, citrus fruits, fatty fish (such as salmon), berries, yogurt, apples, peaches, cauliflower, cabbage, broccoli, and beans, as well as herbs and spices in your meals.
• Avoid smoking: Smoking is a significant risk factor for various cancers, including breast cancer. Quitting smoking or avoiding exposure to secondhand smoke can greatly reduce the risk.
• Limit alcohol consumption: Excessive alcohol consumption is associated with an increased risk of breast cancer. It is advisable to limit alcohol intake or avoid it altogether.
• Choose healthy cooking methods: Opt for healthier cooking methods such as grilling, baking, steaming, or sautéing instead of frying. This helps reduce the intake of unhealthy fats and avoids the formation of potentially harmful substances during high-heat cooking.
• Minimize processed and red meats: Limit the consumption of processed meats (such as sausages, hot dogs, and bacon) as well as red meats (such as beef, pork, and lamb). Instead, choose lean protein sources like poultry, fish, legumes, and nuts.
• Reduce refined carbohydrates and added sugars: Limit the intake of refined carbohydrates found in sugary snacks, pastries, white bread, and sugary beverages. Opt for whole grains and choose natural sources of sweetness like fruits.
• Engage in regular physical activity: Regular exercise, such as brisk walking, jogging, swimming, or cycling, can help maintain a healthy weight and reduce the risk of breast cancer. Aim for at least 150 minutes of moderate-intensity aerobic activity or 75 minutes of vigorous-intensity activity per week.
• Prioritize sleep and rest: Adequate sleep is crucial for overall health. Aim for 7-8 hours of quality sleep each night to support your body's immune system and overall well-being.
• It may cause weakness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
• Nausea may occur upon starting treatment with this medicine but should go away with time. If nausea is bothersome, take it after a meal.
• Your doctor may regularly check your Vitamin D level and bone mineral density and suggest supplements if needed.
• Do not take Aromatin 1 if you are pregnant or breastfeeding.

Indication of Aromatin 1mg Tablet

An anticancer medication is Aromatin 1mg Tablet. In postmenopausal women (those who haven't had a period in a year, signaling the end of the menstrual cycle), it is used to treat early breast cancer. It can be used either on its own or in combination with other therapies like radiation therapy or surgery.

In women who have reached menopause, Aromatin 1mg Tablet is used as the first-line treatment for breast cancer that has progressed to the breast or to other regions of the body. In addition, it is used to treat advanced breast cancer that has gotten worse while receiving Tamoxifen therapy (a medication for treating breast cancer).

Pharmacology

Anastrozole, the active ingredient in Aromatin 1mg Tablet, exerts its anti-estrogenic effect by selectively and competitively inhibiting the enzyme aromatase. Aromatase is predominantly found in the adrenal gland, liver, and adipose tissue. In many cases of breast cancer, the growth of tumors is stimulated and/or sustained by hormones such as estrogen or progesterone.

In postmenopausal women, estrogen is primarily derived from androgens produced by the adrenal glands. Aromatase facilitates the conversion of these androgens into estrogen. By competitively inhibiting the biosynthesis of estrogen through aromatase, Anastrozole effectively reduces circulating estrogen levels. This inhibition of estrogen helps to suppress tumor growth in hormone receptor-positive breast cancers.

By targeting the production of estrogen, Anastrozole plays a crucial role in the treatment of hormone-dependent breast cancer, particularly in postmenopausal women.

Dosage and Administration of Aromatin 1mg Tablet

Adults Including the Elderly: One tablet (1 mg) to be taken orally once a day.
Children: The use of Anastrozole is not recommended in children, as efficacy has not been established
Renal Impairment: No dose change is recommended.
Hepatic Impairment: No dose change is recommended.

Take Aromatin 1mg Tablet as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

Interaction

Taking thalidomide (an immunomodulatory agent) in combination with Aromatin 1mg Tablet can raise the risk of developing dangerous blood clots. It is important to be cautious when using these medications together and consult with your doctor.

Additionally, Aromatin 1mg Tablet may interact with certain medical conditions such as high cholesterol, osteoporosis (weakening of bones), heart disease, and liver disease. It is advisable to inform your doctor about these conditions before taking Aromatin 1mg Tablet to ensure proper monitoring and adjustments to your treatment plan if necessary.

Contraindications

If you are known to be allergic to Anastrozole or any of the excipients of Aromatin 1mg Tablet. If you are pregnant or think you may be pregnant. If you are a breastfeeding mother.

Pregnancy & Lactation

Anastrozole must not be administered during pregnancy or lactation.

Precautions & Warnings

Do not use Aromatin 1mg Tablet if you have allergies to any of its components or if you have not yet reached menopause and are still having menstrual periods. It is important to continue taking Aromatin 1mg tablets prescribed by your doctor for effective treatment of your condition. Do not discontinue the medication without consulting your doctor. Before taking Aromatin 1mg Tablet, discuss with your doctor if you have allergies, osteoporosis (weak bones), a history of bone fractures, high cholesterol levels, or severe liver or kidney disease. Pregnant or breastfeeding women should avoid taking Aromatin 1mg Tablet. The medication may cause weakness and dizziness, so only drive if you are fully alert. Aromatin 1mg Tablet is not recommended for use in children due to a lack of safety data. It is advisable to avoid alcohol consumption while taking Aromatin 1mg Tablet as it can increase drowsiness and dizziness. Inform your doctor about your medical condition and other medications you are taking to ensure there are no potential side effects.

Storage Conditions

Keep below 30°C temperature, protected from light & moisture. Keep out of the reach of children.