Revocon 12.5mg Tablet 10pcs

Uses of Revocon 12.5mg Tablet

Huntington's Disease

How does Revocon 12.5mg Tablet work?

Tetrabenazine works by decreasing the levels of certain chemicals in the body that cause abnormal movements.

Side Effects of Revocon 12.5mg Tablet

Common side effects of Tetrabenazine include depression, suicidality, akathisia, restlessness, agitation, dysphagia, parkinsonism, somnolence, and sedation.

Quick Suggestions:

• You have been prescribed Revocon 25 to help control movement disorders such as Huntington’s disease.
• Be cautious while driving or doing anything that requires concentration as Revocon 25 can cause dizziness and sleepiness.
• Inform your doctor if you experience symptoms such as high fever, sweating, muscle stiffness, and faster breathing. These may be due to a rare side effect known as the neuroleptic malignant syndrome.
• Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
• Do not stop taking Revocon 25 without talking to your doctor first as it may cause worsening of symptoms.

Indication of Revocon 12.5mg Tablet

• Tetrabenazine is used to treat chorea associated with Huntington's disease.

Pharmacology

• Tetrabenazine works by depleting reserves of monoamine neurotransmitters like serotonin, norepinephrine, and dopamine in the basal ganglia. This helps control hyperkinetic movements associated with chorea.
• At dosages of 50 mg, Tetrabenazine may prolong the QTc interval.
• Tetrabenazine or its metabolites may bind to melanin-containing tissues in rats, such as the eyes and skin.

Dosage & Administration of Revocon 12.5mg Tablet

• The chronic daily dose of Tetrabenazine is determined individually for each patient.
• Tetrabenazine therapy should be titrated slowly over several weeks to identify a dose that reduces chorea and is tolerated.
• The maximum recommended daily dose is 100 mg, and the maximum recommended single dose is 37.5 mg.

Interaction

• Tetrabenazine should not be taken with MAOI medication or within 14 days of stopping it.
• It may reduce the effects of levodopa and worsen parkinsonism.
• There is a higher chance of extrapyramidal adverse effects when Tetrabenazine is taken with amantadine, metoclopramide, or antipsychotics.

Contraindications:

• Tetrabenazine is not recommended for patients who are actively suicidal or have untreated or inadequately treated depression.
• It should not be used in conjunction with MAOIs or within 14 days after stopping MAOI therapy.

Pregnancy & Lactation

• Tetrabenazine is classified as Pregnancy Category C. It should only be taken during pregnancy if the potential benefit outweighs the risk to the fetus.
• Tetrabenazine or its metabolites are not known to be excreted in human milk, but a decision should be made whether to stop breastfeeding or stop taking Tetrabenazine, considering the drug's importance to the mother.

Precautions & Warnings

• Tetrabenazine may worsen Parkinsonism symptoms.
• Caution should be maintained while driving or performing specialized duties.
• Use during pregnancy should be carefully considered.

Storage Conditions

Tetrabenazine should be protected from light and moisture and stored in a cool, dry place below 30°C. Keep out of children's reach.