Urodart 0.5mg Capsule 4pcs

Uses of Urodart 0.5mg Capsule

Benign prostatic hyperplasia (enlarged prostate)

How does Urodart 0.5mg Capsule work?

Urodart 0.5mg Capsule contains a 5-alpha reductase inhibitor called dutasteride. It works by blocking the activity of the type II 5-alpha reductase enzymes in the body. These enzymes are responsible for converting testosterone, a normal male hormone, into dihydrotestosterone (DHT), which is a more potent androgen.

By inhibiting the action of type II 5-alpha reductase, dutasteride reduces the production of DHT. High levels of DHT are believed to contribute to the enlargement of the prostate gland in individuals with benign prostatic hyperplasia (BPH). By reducing the levels of DHT, dutasteride helps to shrink the enlarged prostate, thereby alleviating the symptoms associated with BPH.

The inhibition of 5-alpha reductase by dutasteride helps to restore the balance of hormones in the prostate gland, leading to a reduction in the size of the prostate and an improvement in the signs and symptoms of BPH.

Side Effects of Urodart 0.5mg Capsule

• Decreased sperm count
• Impotence
• Decreased libido
• Ejaculation disorder
• Breast enlargement in male
• Breast tenderness in male
• Dizziness
• Altered sexual activity

Quick Suggestions:

• Your doctor has prescribed Urodart 0.5mg Capsule to reduce the size of an enlarged prostate and lower the risk of urinary retention. It may take 3 to 6 months to experience the full benefits of Urodart 0.5mg Capsule, so it is important to continue taking the medication as directed by your doctor. While Urodart 0.5mg Capsule is generally well tolerated, it can cause mild sexual side effects such as decreased sexual drive.
• After completing the course of Urodart 0.5mg Capsule, it is important not to donate blood for 6 months. This precaution is necessary to prevent the transfer of the medication to a pregnant female recipient through a blood transfusion. To avoid any potential risks, it is important to follow this guideline.
• During the course of treatment with Urodart 0.5mg Capsule, it is advisable to avoid consuming grapefruit. Grapefruit can interfere with the metabolism of the medication, potentially affecting its effectiveness.
• A special precaution to take is to use a condom during sexual intercourse. Urodart 0.5mg Capsule has been found in the semen of men taking the capsules. If your partner is pregnant or may become pregnant, it is important to avoid exposing her to your semen, as Urodart 0.5mg Capsule can potentially affect the normal development of a male baby.
• In summary, continue taking Urodart 0.5mg Capsule as prescribed by your doctor, and be aware of potential sexual side effects. Refrain from donating blood for 6 months after completing the medication, avoid grapefruit, and use a condom during sexual activity if your partner is or may become pregnant.

Indication of Urodart 0.5mg Capsule

Dutasteride is indicated for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate to:

• Improve symptoms
• Reduce the risk of acute urinary retention
• Reduce the risk of the need for BPH-related surgery

Pharmacology

Dutasteride is a dual 5-alpha reductase inhibitor, meaning it inhibits both type 1 and type 2 5-alpha reductase enzymes. These enzymes are responsible for the conversion of testosterone to its more potent form, dihydrotestosterone (DHT). By inhibiting both types of 5-alpha reductase, dutasteride effectively reduces the levels of DHT in the body.

DHT plays a crucial role in the development and growth of the prostate gland. Elevated levels of DHT can contribute to the enlargement of the prostate, known as benign prostatic hyperplasia (BPH). Dutasteride's mechanism of action helps to prevent the conversion of testosterone to DHT, thereby reducing the stimulation of prostate tissue growth and alleviating the symptoms associated with BPH.

By inhibiting the production of DHT, dutasteride helps to manage the hypertrophy (enlargement) of the prostatic tissue, which is primarily driven by the effects of DHT. This makes dutasteride an effective medication for treating the signs and symptoms of BPH in adult men.

Dosage & Administration of

The recommended dose is Dutasteride 0.5 mg orally once daily. The capsules should be swallowed whole. Dutasteride may be administered with or without food.

Interaction

Urodart 0.5mg Capsules may interact with several medications and conditions. Here is a summary of the potential interactions:

Drug interactions:

• Blood pressure lowering pills (verapamil or diltiazem): There may be an increased risk of low blood pressure when these medications are taken together with a Urodart 0.5mg Capsule. Close monitoring of blood pressure is recommended.
• HIV medicines (ritonavir or indinavir): These medications can increase the blood levels of Urodart 0.5mg Capsule, potentially leading to an increased risk of side effects. Dosage adjustments may be necessary.
• Fungal infections (itraconazole or ketoconazole): These medications can increase the blood levels of Urodart 0.5mg Capsule, potentially leading to an increased risk of side effects. Dosage adjustments may be necessary.
• Antidepressant (nefazodone): There may be an increased risk of side effects when nefazodone is taken together with Urodart 0.5mg Capsule. Close monitoring is recommended.
• Enlarged prostate medication (prazosin): Prazosin and Urodart 0.5mg Capsule may have additive effects in lowering blood pressure. Close monitoring of blood pressure is advised.

Drug-food interaction:

• Grapefruit: It is advisable to avoid consuming grapefruit or grapefruit juice while taking Urodart 0.5mg Capsule. Grapefruit can interfere with the metabolism of the medication, potentially increasing its blood levels and the risk of side effects.

Drug-disease interaction:

• Liver disease: Individuals with liver disease should not take Urodart 0.5mg Capsule, as the medication is metabolized in the liver. Liver impairment can affect the clearance of the drug and increase the risk of side effects.

Contraindications

Dutasteride is not recommended for women or children, as well as those who have a known hypersensitivity to it or other 5 a-reductase inhibitors. Warnings: Women in danger of being exposed to a male fetus: Dutasteride is a topical medication that is absorbed through the skin. Because of the probability of Dutasteride absorption and the risk of a fetal anomaly in a male baby, women who are pregnant or may be pregnant should avoid handling Dutasteride capsules. If you come into contact with leaking capsules, wash the area with soap and water right away.

Pregnancy & Lactation

Urodart 0.5mg Capsule is specially designed for men. Pregnant women should not come in contact with this medicine, as it gets absorbed via the skin and can adversely affect the growing fetus. Thus, pregnant women should avoid contact with this medicine. It should also not be used by nursing mothers.

Precautions & Warnings

Before starting Urodart 0.5mg Capsule, it is important to follow the guidelines and precautions mentioned:

• Allergy: Inform your doctor if you have any allergies to any component of the Urodart 0.5mg Capsule.
• Severe liver disease: If you have severe liver disease, it is important to inform your doctor before taking Urodart 0.5mg Capsule. The medication may require special considerations or dosage adjustments in individuals with impaired liver function.
• Use in men only: Urodart 0.5mg Capsule is intended for use in men only and should not be used by women. It is not approved for use in women.
• Women: If you are a woman using Urodart 0.5mg Capsule (which is not recommended), inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. The medication can potentially cause harm to the developing fetus, and precautions should be taken to avoid exposure during pregnancy or breastfeeding.
• Blood donation: Do not donate blood while taking Urodart 0.5mg Capsule and for at least 6 months after discontinuing the medication. This is to prevent the exposure of dutasteride to a pregnant female transfusion recipient.
• Discontinuation: Do not stop taking Urodart 0.5mg Capsule without informing your doctor first. It may take up to 6 months or more to observe the full effects of the medication, so it is important to follow your doctor's instructions.
• Use in children: Urodart 0.5mg Capsule is not recommended for use in children. It should not be given to children.

Storage Conditions

• Store below 30°C in the original package.
• Keep this medicine out of the sight and reach of children and pets.
• Do not use this medicine after the expiry date.
• Do not throw away any medicines via wastewater or household waste.