Generic Name: Baclofen 25mg
Manufacturer/Distributor: Aristopharma Limited
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Indications of Flexibac 25
Baclofen is used to treat skeletal muscle spasms caused by rheumatic disorders, spinal cord injuries, and other spinal diseases, as well as spasticity caused by multiple sclerosis, flexor spasms and pain, clonus, and muscular rigidity.
Cerebrovascular accidents, tumors, and degenerative brain disease are all possible causes.
Pharmacology of Flexibac 25
By stimulating GABAB receptors, which block glutamate and aspartate release, baclofen inhibits monosynaptic and polysynaptic reflexes in the spinal cord. Acting at intraspinal sites, it may also cause CNS depression. Baclofen also has an antinociceptive effect.
Administration & Dosage
5 mg three times a day, preferably with or after food, gradually increased to a maximum of 100 mg per day.
Interaction of Flexibac 25
Baclofen may cause increased sedation when combined with central nervous system depressants, alcohol, or synthetic opiates. Respiratory depression is also a possibility.
Because combining Baclofen with antihypertensives is likely to result in a greater drop in blood pressure, the antihypertensive medication dosage should be adjusted accordingly.
Contraindications
Baclofen is not recommended for patients who are hypersensitive to any of the product's ingredients.
Side Effect of Flexibac 25
Baclofen's most common side effects are transient drowsiness, daytime sedation, dizziness, weakness, and fatigue. The central nervous system is characterized by headache (ten percent), insomnia (ten percent), and euphoria, excitement, depression, confusion, hallucinations, paraesthesia, nightmares, muscle pain, tinnitus, slurred speech, co-ordination disorder, tremor, rigidity, dystonia, and ataxia.
Pregnancy & Lactation
The most common side effects of Baclofen are transient drowsiness, daytime sedation, dizziness, weakness, and fatigue.
Headache (ten percent), insomnia (ten percent), and euphoria, excitement, depression, confusion, hallucinations, paraesthesia, nightmares, muscle pain, tinnitus, slurred speech, co-ordination disorder, tremor, rigidity, dystonia, and ataxia are all symptoms of the central nervous system.
Precautions & Warnings
Patients with impaired renal function or those undergoing chronic hemodialysis should receive lower doses (approximately 5 mg per day). Patients with spasticity, as well as psychotic disorders, schizophrenia, depressive or manic disorders, or confusional states, should be treated with caution and closely monitored, as these disorders may worsen. Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
Storage Conditions
Store below 30°C, away from light, in a cool, dry place. Keep out of children's reach.