Zolium 0.5mg Tablet | Alprazolam | Dosage | Price | Interaction | ePharma
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Zolium 0.5mg Tablet

Generic: Alprazolam

Type: Tablet

Pack Size: 10 Pcs

Zolium 0.5mg Tablet is an effective drug prescribed to patients who have panic disorders and anxiety disorders as a result of depression. The drug controls the levels of certain unbalanced chemicals released by the brain in patients who suffer from depression.

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Discount Price: ৳ 32.55
MRP: ৳ 35 7% Off

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Zolium 0.5mg Tablet contains Alprazolam, an anxiolytic used to treat generalized anxiety disorder and panic disorder. Avoid alcohol during treatment as it can increase the effects. Look out for signs of suicidality or worsening depression and inform the doctor immediately. Avoid use in severe liver disease, myasthenia gravis, sleep apnea, and severe breathing difficulties. Inform your doctor about kidney, liver, lung problems, mental illness, drug or alcohol abuse, or suicidal thoughts before taking. Consult your doctor before using during pregnancy; breastfeeding is not recommended. Not for use in children and adolescents under 18. Use with caution in the elderly. Common side effects include headaches, constipation, dry mouth, tiredness, irritability, depression, nausea, and vomiting. Seek immediate medical attention if symptoms worsen or persist.

Safety Advices


Consumption of alcohol is not recommended during treatment with Zolium 0.5mg Tablet due to the increased risk of serious side effects. 


Zolium 0.5mg Tablet is not recommended for use during pregnancy as it is known to cause serious side effects in the fetus. Your doctor may prescribe a safer alternative with the same therapeutic effect based on your condition.


Zolium 0.5mg Tablet passes into the breastmilk and hence it is not recommended to be used in breastfeeding. Your doctor may prescribe a safer alternative with the same therapeutic effect based on your condition.


Do not drive or use machines while taking Zolium 0.5mg Tablet as it can make you feel sleepy, dizzy, or less focused.


Zolium 0.5mg Tablet should be used with caution in patients with kidney problems. Consult your doctor before taking it.


Zolium 0.5mg Tablet is not recommended for use in patients with severe liver problems. Zolium 0.5mg Tablet should be used with caution in patients having any other liver problems. Consult your doctor before taking it.

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Uses of Zolium 0.5mg Tablet
  • Anxiety
  • Panic disorder
how does Zolium 0.5mg Tablet work?

Zolium 0.5mg Tablet binds to certain receptors in your brain and nervous system and it enhances the activity of a chemical substance called gamma-aminobutyric acid (GABA) which helps to produce a calming effect in your brain.

Side Effects of Zolium 0.5mg Tablet
  • Changes in the pattern of speech
  • Unsteadiness
  • Loss of coordination
  • Drowsiness
  • Blurred vision
  • Abdominal pain
  • Difficult or painful urination
  • Headache
  • Chest pain
  • Irregular menstrual periods
  • Decreased appetite
  • Weight loss
  • Double vision
  • Sudden sweating
  • Acid or sour stomach
  • Heartburn
Quick Suggestions:
  • Follow a regular sleep pattern and avoid daytime naps to promote better sleep at night.
  • Avoid watching TV, or using mobiles, or laptops just before bedtime, as it may interfere with your sleep.
  • Maintain a diet rich in fruits, vegetables, and whole grains while avoiding fried foods, high-fat dairy products, pastries, and processed foods that may worsen anxiety.
  •  Engage in regular exercise and maintain a healthy body weight to support overall well-being.
  • Refrain from consuming alcohol, as it may increase drowsiness and interact with Zolium 0.5mg Tablet.
  • Be aware of the high addiction/habit-forming potential of Zolium 0.5mg Tablet. Take it only as prescribed by your doctor and avoid increasing the dose or duration without medical advice.
  • Zolium 0.5mg Tablet may cause dizziness. Avoid activities that require mental focus, such as driving, until you know how the medicine affects you.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding before using Zolium 0.5mg Tablet.
  • Do not stop taking the medication suddenly without consulting your doctor, as it may lead to withdrawal symptoms like nausea, anxiety, agitation, sweating, tremor, and confusion.
  • Avoid using Zolium 0.5mg Tablet for an extended period, as it may lead to mental or physical dependence on the medication.
  • Always follow your doctor's advice and discuss any concerns or questions you may have about the medication. Adhering to these guidelines can help ensure safe and effective use of Zolium 0.5mg Tablet for managing anxiety-related conditions.
Indication of Zolium 0.5mg Tablet
  • Anxiety disorder is treated with alprazolam.
  • Anxiety alleviation in the short term Anxiety and depression are linked.
  • Panic disorder, whether or not agoraphobia is present.

Zolium 0.5 (Alprazolam) is a triazole analog belonging to the 1,4-benzodiazepine medication family. It exerts its effects as an anxiolytic (anti-anxiety), hypnotic (sleep-inducing), and anticonvulsant (anti-seizure) agent. The mechanism of action of Alprazolam involves the enhancement of the inhibitory neurotransmitter Gamma-Aminobutyric Acid (GABA) through its interaction with the GABA-benzodiazepine receptor complex in the central nervous system (CNS).

By enhancing the effects of GABA, Alprazolam produces a dose-dependent CNS depressive effect, which can range from moderate impairment of task performance to inducing sleep (hypnosis). This makes Alprazolam effective in treating conditions like anxiety disorders, panic disorder, and certain types of seizures.

However, it's important to use Alprazolam with caution, as its CNS depressive effects can lead to drowsiness, sedation, and impairments in cognitive and motor functions. Long-term use or misuse of Alprazolam can also lead to dependence and withdrawal symptoms if abruptly discontinued. Therefore, it should be used as directed by a healthcare professional and not be abruptly stopped without medical supervision.

Dosage & Administration of Zolium 0.5mg Tablet

The recommended initial dose of Zolium 0.5 (Alprazolam) is 0.25 to 0.5 mg three times daily. Depending on the individual's response, the dose may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. The maximum daily dose should not exceed 4 mg. In some cases of panic disorder, patients may require higher doses, up to 10 mg per day, but this should be done under close supervision with periodic reassessment.

Dosage should be tailored to each patient to achieve the maximum therapeutic effect with the lowest possible dose. If side effects occur at the starting dose, the dose may be lowered. When discontinuing therapy, the dose should be gradually reduced by no more than 0.5 mg every three days.

For elderly patients or those with advanced liver disease, the usual starting dose is 0.25 mg, two or three times daily, and it may be gradually increased if needed and tolerated.

Zolium 0.5 (Alprazolam) 1 mg should be administered once daily, preferably in the morning, for patients who are on multiple dosage regimens of Alprazolam 0.25/0.5 mg. The tablets should be taken intact and should not be chewed, crushed, or broken. It is important to follow the prescribed dosage and administration instructions provided by the healthcare provider.


Drug-Drug Interactions: Zolium 0.5mg Tablet may interact with medications used to treat anxiety or depression, painkillers, antihistamines/antiallergics, antifungals, oral contraceptives, certain antibiotics, medications for stomach ulcers, drugs for angina and high blood pressure, heart medications, HIV drugs, antipsychotic medications, and drugs for epilepsy.

Drug-Food Interactions: Avoid consuming alcohol while taking Zolium 0.5mg Tablet as it may increase side effects such as drowsiness, dizziness, or difficulty concentrating.

Drug-Disease Interactions: Inform your doctor if you have narrow-angle glaucoma, myasthenia gravis, pulmonary insufficiency, or kidney/liver problems before takingZolium 0.5mg Tablet.


If you are allergic to alprazolam or other ingredients present in the tablet. If you suffer from a very weak and tired muscle condition (myasthenia gravis). If you have severe chest problems and irregular breathing difficulties even while sleeping (chronic bronchitis, sleep apnoea). If you have severe liver problems. If you are on antifungal medicine such as ketoconazole and itraconazole. If you have narrow-angle glaucoma (increased pressure within the eye).

Pregnancy & Lactation

Alprazolam is classified as a pregnancy category D drug, indicating that it may cause harm to the fetus if taken during pregnancy. It is not recommended for use in pregnant women.

Furthermore, Alprazolam, being a benzodiazepine, is likely to be secreted in breast milk. Therefore, breastfeeding should be avoided by mothers who are taking Alprazolam to prevent any potential adverse effects on the nursing baby. It is essential for nursing mothers to consult their healthcare provider for suitable alternatives if needed.

Precautions & Warnings
  • Allergy: Do not take Zolium 0.5mg Tablet if you are allergic to it.
  • Age restriction: This medication is not recommended for individuals below 18 years of age.
  • Pregnancy and breastfeeding: Avoid Zolium 0.5mg Tablet during pregnancy and breastfeeding as it may harm the baby.
  • Elderly patients: Use with caution in elderly patients due to an increased risk of adverse reactions.
  • Medical conditions: Inform your doctor if you have myasthenia gravis, drug addiction, chronic pulmonary insufficiency, narrow-angle glaucoma, or kidney/liver problems before taking Zolium 0.5mg Tablet
  • Opioids: Do not combine Zolium 0.5mg Tablet with opioids as it may cause breathing problems, drowsiness, and coma.
  • Do not throw the medication into household waste or wastewater. Ask your pharmacist about the proper disposal of medicines no longer required.
Storage Conditions
  • Keep this medicine out of the sight and reach of children.
  • Do not use this medicine after the expiry date which is stated on the carton.
  • Do not store it above 25°C.
Frequently Asked Questions (FAQ)

The effect of Zolium 0.5mg Tablet can be observed within 40-60 minutes of administration of the dose. You may start feeling relaxed within an hour of intake of this medicine.

Zolium 0.5mg Tablet remains effective in the body for about six hours.

No, Alprazolam is not an anti-depressant. It is used to relieve excess anxiety and to treat anxiety associated with depression.




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ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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