Abasaglar SC Insulin | 3ml | Cartridge | 100IU/ml | Glargine | ePharma
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Abasaglar SC Insulin-3ml Cartridge

Generic: Insulin Glargine (rDNA)

Type: Cartridge

Pack Size: 1 Pc

Insulin Glargine is used in the treatment of Diabetes Mellitus (Type 1 & Type 2).

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Abasaglar SC Insulin-3ml Cartridge and its uses in treating diabetes mellitus. Abasaglar SC Insulin-3ml Cartridge is a long-acting insulin containing insulin glargine, a modified insulin similar to human insulin. It helps regulate blood sugar levels throughout the day by providing a steady and consistent blood-sugar-lowering action. Here's a summary of the key points you mentioned:

  • Abasaglar SC Insulin-3ml Cartridge contains insulin glargine, a modified insulin that closely resembles human insulin. It is used to treat diabetes mellitus in individuals aged two years and above.
  • Abasaglar SC Insulin-3ml Cartridge works by providing a consistent and uniform blood-sugar-lowering effect over a 24-hour period. It takes about 2 hours to start acting and does not have a pronounced peak activity.
  • This is a disease in which the body does not produce enough insulin to regulate blood sugar levels. Abasaglar SC Insulin-3ml Cartridge helps manage diabetes by providing the needed insulin.
  • Your doctor will determine the appropriate dosage of Abasaglar SC Insulin-3ml Cartridge based on your lifestyle, blood sugar test results, and previous insulin usage. It's important to follow your doctor's instructions.
  • Injection site reactions such as lumps under the skin can occur. To prevent these, it's advised to rotate injection sites. Some side effects, like injection site reactions, sweating, and anxiety due to low blood sugar (hypoglycemia), are common but usually resolve over time.
  • Do not stop taking Abasaglar SC Insulin-3ml Cartridge on your own, as it can lead to withdrawal symptoms. Inform your doctor before making any changes. This medication is not suitable for individuals with low blood glucose levels, kidney, liver, or heart problems, or issues with alcohol or recreational drugs.
  • Along with using Abasaglar SC Insulin-3ml Cartridge, maintaining a healthy diet, regular exercise, and weight management are important aspects of diabetes management. Abasaglar SC Insulin-3ml Cartridge is a cold chain medicine and should be stored in the refrigerator between 2-8 degrees Celsius; avoid freezing it

Safety Advices


Refrain from consuming alcohol while using Abasaglar SC Insulin-3ml Cartridge, as it can lead to fluctuations in blood sugar levels.


If you're pregnant, suspect you might be pregnant, or are planning to have a baby, consult your doctor before using Abasaglar SC Insulin-3ml Cartridge. Careful diabetes control, including preventing hypoglycemia, is essential for both your health and the health of the baby. Your doctor will adjust the dose as necessary.


If you're breastfeeding, inform your doctor before using Abasaglar SC Insulin-3ml Cartridge, as it's unclear whether it's excreted in breast milk. Your doctor will consider adjustments to the dose and diet as needed.


Avoid driving or using machinery while using Abasaglar SC Insulin-3ml Cartridge, as blood sugar levels can affect concentration and reaction times. If you frequently experience hypoglycemia episodes, consult your doctor.


Exercise caution when using Abasaglar SC Insulin-3ml Cartridge if you have kidney disease. Your doctor will adjust your dose based on factors such as age, body weight, and disease condition.


Approach Abasaglar SC Insulin-3ml Cartridge with caution if you have liver disease. Your doctor will determine the appropriate dose adjustments based on your age, body weight, and liver condition.

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Uses of Abasaglar SC Insulin-3ml Cartridge
  • Type 1 Diabetes Mellitus
  • Type II Diabetes Mellitus
How does Abasaglar SC Insulin-3ml Cartridge work?

Abasaglar SC Insulin-3ml Cartridge is a long-acting modified form of insulin that works similarly to human insulin. It improves blood sugar control by enhancing glucose uptake from the blood into body tissues and also by preventing the production of glucose in the liver.

How to self-administer Abasaglar SC Insulin-3ml Cartridge

These instructions are important for individuals who need to manage their diabetes and administer insulin on their own. Here's a summarized version of the self-injection procedure:


  • Wash your hands before handling insulin.
  • Gently roll the insulin bottle between your palms.
  • Wipe the rubber top of the insulin bottle with an alcohol swab.

Prepare the Syringe:

  • Pull the plunger of the syringe down to the prescribed number of insulin units.
  • Push the needle into the insulin bottle and push the syringe plunger down to draw the required dose.
  • Once again, pull the plunger down to the prescribed units to ensure accuracy.

Injection Site Preparation:

  • Select an injection site (upper arm, thigh, or abdominal wall).
  • Clean the chosen site with an alcohol swab.
  • Pinch up the skin at the injection site.

Administer the Injection:

  • Insert the needle into the pinched-up skin at a 90-degree angle.
  • Push the plunger in to inject the insulin.
  • Keep the needle under the skin for at least 6 seconds to ensure the complete dose is delivered.

After Injection:

  • Withdraw the needle gently.
  • Safely dispose of the used syringe in a sharps container.
  • You can have your meal or snack as prescribed.

Injection Site Rotation:

  • Change (rotate) your injection sites within the chosen area for each dose.
  • This practice reduces the risk of developing lipodystrophy (pitted or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites.
  • Do not repeatedly use the same spot for injections.
  • Avoid injecting where the skin is pitted, thickened, lumpy, tender, bruised, scaly, hard, scarred, or otherwise damaged.

It's important to note that these instructions are a general guide. Patients should always follow the specific instructions provided by their healthcare provider and should receive proper training on insulin injection techniques. If any concerns or uncertainties arise, individuals should consult their healthcare professional for clarification and guidance. Proper insulin administration is crucial for effective diabetes management.

Side Effects of Abasaglar SC Insulin-3ml Cartridge
  • Decreased blood glucose levels
  • Reaction at the injection site
  • Skin Rash
  • Thickening or hollowing of the skin at the injection site
  • Weight gain
Quick Suggestions:
  • Insulin Glargine is injected under the skin. It needs to be injected once daily, at the same time every day.
  • Injection below the skin of the abdomen results in faster absorption than other injection sites.
  • Injection sites must be rotated to prevent hard lumps from developing at one site.
  • Exercise regularly, eat a healthy diet, and take your other diabetes medicines (if prescribed) alongside.
  • Hypoglycemia (low blood sugar level) is a common side effect. Hence, regular monitoring of blood sugar levels is required while taking this medicine.
  • Always carry some high-sugar food such as sugar candy or glucose candy, fruit juice, and Glucose with you so that you can take it when you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremors, weakness, and anxiety.
  • Opened vials/cartridges stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator (2°C–8°C).
  • Do not use it if the preparation is no longer clear and colorless, or if it contains particles.
Indication of Abasaglar SC Insulin-3ml Cartridge

Abasaglar SC Insulin-3ml Cartridge is used for the treatment of diabetes in children and adults. It is a long-acting insulin that consistently works for several hours after injection and provides effective blood sugar control throughout the day.


Sterile Solution: Insulin glargine is a sterile solution intended for subcutaneous injection. It's administered via injection to manage blood sugar levels in individuals with diabetes.

Recombinant Human Insulin Analog: Insulin glargine is a synthetic version of human insulin that has been modified to have a longer duration of action. It falls under the category of long-acting parenteral hypoglycemic agents, meaning it helps lower blood sugar levels over an extended period.

Long-Lasting Action: One of the significant attributes of insulin glargine is its prolonged action, which can last up to 24 hours. This prolonged action helps provide consistent blood sugar control throughout the day.

Recombinant DNA Technology: Insulin glargine is produced using recombinant DNA technology, a biotechnological process that involves manipulating DNA to create the desired product. In this case, the goal is to produce insulin glargine that closely mimics the effects of natural insulin.

Regulation of Glucose Metabolism: The primary function of insulin glargine is to regulate glucose metabolism in the body. It helps lower blood sugar levels by facilitating glucose absorption in peripheral tissues, mainly skeletal muscle, and fat. Additionally, it inhibits the liver's production of glucose.

Effects on Lipolysis, Proteolysis, and Protein Synthesis: Insulin glargine and other insulin analogs have a variety of effects on metabolism. They inhibit lipolysis (breakdown of fats), and proteolysis (breakdown of proteins), and promote protein synthesis. These actions contribute to overall metabolic balance.

This information highlights the scientific basis of insulin glargine and its role in managing diabetes by effectively regulating blood sugar levels. As always, individuals with diabetes should work closely with their healthcare providers to determine the most appropriate treatment plan, including the use of insulin glargine, to ensure optimal blood sugar control and overall health.

Dosage & Administration of Abasaglar SC Insulin-3ml Cartridge

Adult Dose:

  • For Type 1 Diabetes: Start with approximately one-third of the total daily insulin requirements. The remaining two-thirds should be fulfilled by short-acting, premeal insulin. Insulin glargine is used in combination with short-acting or rapid-acting insulin.
  • For Type 2 Diabetes: Initial dose for patients not on insulin is 10 units (or 0.2 units/kg) once daily. Dosage should be individualized based on blood glucose measurements.
  • Converting from other insulins: Adjustments in the timing and amounts of shorter-acting insulins may be needed.

Child Dose: For children with Type 1 Diabetes:

  • <6 years: Safety and efficacy are not established.

6 years: Start with about one-third of the total daily insulin requirements subcutaneously. Rapid-acting or short-acting insulin should cover the remaining two-thirds. Usual daily maintenance in adolescents is <1.2 units/kg/day during growth spurts.

Renal Dose: Dose adjustments might be necessary for individuals with renal impairment.

Dosing Considerations: Insulin glargine is meant for once-daily subcutaneous administration at the same time every day. It exhibits a relatively constant glucose-lowering profile over 24 hours. Blood glucose monitoring is crucial to determine the appropriate dose. Injection sites should be rotated to avoid lipodystrophy.

Exercise and Other Factors: Factors like exercise, stress, illness, changes in coadministered drugs, and meal patterns can affect insulin absorption, onset, and duration of action.


  • Insulin glargine is administered subcutaneously (under the skin) in the upper arm, thigh, or abdominal wall. Injecting into the abdominal wall leads to faster absorption. It should not be administered intravenously (IV) or via an insulin pump, as IV administration of the standard subcutaneous dose can cause severe hypoglycemia.

As always, individuals with diabetes should work closely with their healthcare providers to determine the most suitable dosing regimen for insulin glargine and other aspects of their diabetes management. Personalized treatment plans, regular blood sugar monitoring, and adherence to medical advice are essential for effective diabetes control.


Drug-Drug Interactions:

  • Abasaglar SC Insulin-3ml Cartridge may interact with various medications, including:
    • Antidiabetic pills (e.g., sitagliptin)
    • Blood sugar enhancers (e.g., diazoxide)
    • Blood pressure-lowering pills (e.g., metoprolol, clonidine)
    • Antidepressants (e.g., lithium, fluoxetine)
    • Pain killers (e.g., aspirin, pentoxifylline, propoxyphene)
    • Anti-TB drug (isoniazid)
    • Growth hormone (somatropin)
    • Thyroid hormone-related drugs (e.g., levothyroxine)
    • Antipsychotic medicines (e.g., phenothiazine, clozapine, olanzapine)
    • Anti-cholesterol drugs (e.g., fenofibrate)
    • Anti-asthmatic medications (e.g., epinephrine, salbutamol, terbutaline)
    • Female hormones (e.g., estrogens and progestogens)

Drug-Food Interactions:

  • Abasaglar SC Insulin-3ml Cartridge may interact with alternative medicine products like ayurvedic, homeopathy, Unani, herbal supplements, or over-the-counter (OTC) items. It's important to inform your doctor if you are using any of these products. Additionally, it's advised to avoid consuming alcoholic beverages while using Abasaglar SC Insulin-3ml Cartridge, as alcohol can affect blood sugar levels.

Drug-Disease Interactions:

  • Abasaglar SC Insulin-3ml Cartridge should not be used by individuals with certain medical conditions, including:
    • Kidney disease
    • Liver disease
    • Low blood sugar/glucose level (hypoglycemia)
    • Low potassium level (hypokalemia)
  • If you are allergic to insulin or any of the ingredients of this medicine.
  • If you are suffering from hypoglycemia (low blood sugar level).
Pregnancy & Lactation


  • Insulin glargine is categorized as Pregnancy Category C. This means that it should be used during pregnancy only if the potential benefits to the mother outweigh the potential risks to the fetus. Pregnant women should consult their healthcare provider to discuss the risks and benefits before using insulin glargine.


  • It's not known whether insulin glargine is excreted in human breast milk. Many drugs, including human insulin, can pass into breast milk. Therefore, caution should be exercised when administering insulin glargine to nursing women.
  • Women who are breastfeeding may need adjustments to their insulin dosage and dietary considerations. Careful monitoring and guidance from a healthcare provider are essential to ensure proper management.
Precautions & Warnings
  • Abasaglar SC Insulin-3ml Cartridge is intended for subcutaneous (under the skin) use only and should never be administered intravenously (IV) or in the veins.
  • If you're changing the brand of insulin or need to change your injection method, it should be done under strict medical supervision.
  • Cases of heart failure were reported when pioglitazone was used with insulin, especially in patients at high risk of cardiac heart failure.
  • Initial symptoms of high blood sugar (hyperglycemia) may include excessive thirst, dry mouth, increased urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite, and acetone odor of the breath. These symptoms should be closely monitored.
  • Use caution when using Abasaglar SC Insulin-3ml Cartridge in individuals with renal or hepatic impairment (kidney or liver problems).
  • Use during pregnancy should be carefully considered, with the potential benefit weighed against the possible risk to the fetus. Medical guidance is crucial.
  • Abasaglar SC Insulin-3ml Cartridge is considered safe for use during breastfeeding, but medical advice should still be sought before using it while breastfeeding.
  • Abasaglar SC Insulin-3ml Cartridge is not recommended for use in children under 6 years old.
  • When transitioning from one insulin regimen to another, medical supervision is necessary to ensure proper dosing and management.
  • Regular monitoring of serum glucose levels, potassium, electrolytes, HbA1c (glycated hemoglobin), and lipid profile (cholesterol and triglycerides) is important.
  • Extra caution should be exercised if using Abasaglar SC Insulin-3ml Cartridge during concurrent illness, particularly infections.
  • Symptoms such as heart failure, weight gain, and fluid retention (edema) should not be ignored or dismissed.
  • It's advisable to avoid alcohol consumption, as it can potentially affect blood glucose levels.
  • Traveling across more than two time zones requires caution. Your doctor may need to adjust your insulin schedule to accommodate changes in time zones.
  • Abasaglar SC Insulin-3ml Cartridge may decrease potassium levels, leading to hypokalemia. If left untreated, this condition could result in respiratory paralysis, irregular heartbeat rhythm, coma, and even death.
  • Do not use Abasaglar SC Insulin-3ml Cartridge if you have low blood glucose levels, kidney, liver, or heart problems, or issues with alcohol or other prescription recreational drugs.
Storage Conditions
  • Store it between 2°C to 8°C in the refrigerator.
  • Do not freeze it.
  • Keep it out of the reach of children.
  • Do not open the carton of vials to protect it from light.
  • Any unused portion should not be stored and should be appropriately discarded.
Frequently Asked Questions (FAQ)

Insulin glargine, being a long-acting insulin, is typically prescribed to be taken once a day. It's important to take it at the same time every day to maintain consistent blood sugar control.

Consult Your Doctor: Consult your doctor for guidance on adjusting your insulin dose in various situations. Illness: Monitor blood sugar closely when you're ill, as it can affect your levels. Medication: Inform your doctor about all medications, as they can impact insulin's effects and require dose adjustments. Eating Habits: Changes in eating habits, like eating less, skipping meals, or overeating, can affect your insulin needs. Lifestyle Factors: Your blood sugar can be affected by exercise, alcohol consumption, and stress. Pregnancy and Breastfeeding: Pregnant and breastfeeding mothers should consult their doctor, as insulin needs may change.

Abasaglar SC Insulin-3ml Cartridge for Injection is a synthetic insulin resembling human insulin. It exhibits a consistent and prolonged effect on blood sugar levels, lasting throughout the day. Usage Frequency: Due to its extended action, it's administered once daily. Indications: It's employed to manage type 2 diabetes in adults and type 1 diabetes in both adults and children.

Abasaglar SC Insulin-3ml Cartridge begins to show its effect within 1.5 to 2 hours after administration.

The effect of Abasaglar SC Insulin-3ml Cartridge lasts for an average duration of 24 hours.
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ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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