MET 500 | Antihyperglycemic | Biguanide | Type 2 Diabetes | ePharma
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MET 500mg Tablet 10pcs

Generic: Metformin Hydrochloride

Type: Tablet

Pack Size: 10 Pcs

Met 500 is used to treat type 2 diabetes mellitus and Polycystic Ovary Syndrome (PCOS) in women. It helps control blood sugar levels and prevent diabetes-related complications.


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Discount Price: ৳ 37.2
MRP: ৳ 40 7% Off

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✅ Description:

  • Metformin Hydrochloride Tablet helps maintain balanced blood sugar levels and is used to treat Type 2 diabetes, heart disorders, and polycystic ovary syndrome.
  • Decreases glucose production by the liver, suppressing its release in the body.
  • Increases insulin sensitivity, allowing better absorption of glucose by the body.
  • Manages blood sugar levels to prevent complications like kidney failure, obesity, and heart disorders.
  • Does not increase insulin but decreases sugar production by the liver.
  • Reduces appetite and enhances insulin sensitivity, lowering blood glucose levels.
  • Aids in weight loss and decreases cholesterol levels.
  • Pregnant women, breastfeeding mothers, and children below ten years should avoid this medication.
  • Inform your doctor about liver disease, kidney disorders, heart disease, allergies, and diabetic ketoacidosis.
  • Avoid alcohol consumption to reduce the risk of lactic acidosis.
  • The doctor determines the dosage based on age, condition severity, and other medications.
  • Follow the prescribed course without skipping doses.
  • Seek immediate medical attention if any side effects are detected.
  • Hypoglycemia is not observed with standard doses; overdosage can lead to lactic acidosis.
  • Hemodialysis may be useful for removing excess drugs in suspected overdosage cases.

Safety Advices


Alcohol
UNSAFE

Consumption of alcohol with Met 500 is considered unsafe. It may lead to adverse effects.


Pregnancy
CONSULT YOUR DOCTOR
  • Met 500 is generally considered safe to use during pregnancy. Limited human studies show low or no adverse effects on the developing baby

Breastfeeding
CONSULT YOUR DOCTOR

Met 500 is probably safe during breastfeeding. Limited human data suggests minimal risk to the baby.


Driving

Driving ability may be affected if blood sugar levels are too low or too high. Avoid driving if experiencing symptoms related to blood sugar fluctuations.


Kidney
  • Met 500 should be used cautiously in patients with kidney disease. Dose adjustment may be necessary, and regular monitoring of kidney function is advisable.

Liver
  • Met 500 should be used with caution in patients with liver disease. Dose adjustment may be required. It is generally initiated with a low dose in mild to moderate liver disease, and its use is not recommended in severe liver disease.

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✔️ Uses of MET 500

Type 2 Diabetes Mellitus, Polycystic Ovary Syndrome (PCOS), Obesity, Cardiovascular Diseases, Hypertension, 

✔️ How does MET 500 work?

Metformin, the active ingredient, is a biguanide with antihyperglycaemic effects. It lowers both basal and postprandial plasma glucose by various mechanisms.

✔️ Side Effects of MET 500

Common side effects include anorexia, nausea, vomiting, diarrhea, weight loss, occasional metallic taste, weakness, hypoglycemia, rash, and malabsorption of vitamin B12.

✔️ Quick Suggestions:
  • Follow the diet and exercise program recommended by your doctor to effectively control diabetes.
  • Regularly monitor blood sugar levels to detect and manage hypoglycemia, especially when combined with other antidiabetic medicines or alcohol.
  • Inform your doctor if you experience symptoms like deep or rapid breathing, persistent nausea, vomiting, or stomach pain, as these may indicate a rare but serious condition called lactic acidosis.
  • Prolonged use of Met 500 may lead to vitamin B12 deficiency, resulting in anemia. Notify your doctor if you experience symptoms like fatigue, pale skin, shortness of breath, or headache.
  • Your doctor will regularly monitor blood sugar levels and kidney functions while you are on Met 500.
✔️ Indications of Metformin Hydrochloride

Type II Diabetes Mellitus:

Diabetes mellitus (DM) is a health condition characterized by elevated blood sugar levels. It occurs due to insufficient insulin production or the body's inability to effectively use insulin. Insulin is a hormone produced by the pancreas, and it plays a crucial role in converting glucose from food into energy. There are two main types of diabetes:

  • Type I DM: This type involves little to no production of insulin by the pancreas.
  • Type II DM: This type is characterized by insulin resistance, where the body's cells do not respond properly to insulin. MET 500 Tablet is used to help regulate blood glucose levels in individuals with type 2 diabetes, both in adults and children.

Polycystic Ovary Syndrome (PCOS):

Polycystic ovary syndrome is a hormonal disorder affecting women of reproductive age. It involves the enlargement of ovaries with cysts formed on the outer lining. PCOS is associated with hormonal imbalances, irregular menstrual cycles, and other symptoms. MET 500 Tablet is sometimes used in the treatment of PCOS.

MET 500 Tablet:

  • Usage in Type 2 Diabetes: Helps in reducing blood glucose levels by addressing insulin resistance.
  • Usage in PCOS: Can be used in the management of Polycystic ovary syndrome to address hormonal imbalances.
✔️ Pharmacology
  • Reduces both baseline and postprandial plasma glucose levels.
  • Differs from sulfonylureas and does not induce hypoglycemia.
  • Enhances insulin sensitivity.
  • Increases peripheral glucose uptake and utilization.
  • Lowers hepatic glucose production.
  • Reduces intestinal glucose absorption.
  • Metformin is effective in treating type 2 diabetes by targeting multiple aspects of glucose metabolism.
  • It is known for improving insulin sensitivity, reducing glucose production by the liver, and decreasing intestinal glucose absorption.
  • Unlike some other antidiabetic medications, metformin does not stimulate insulin secretion, minimizing the risk of hypoglycemia.
  • The overall effect is a better control of blood sugar levels in individuals with type 2 diabetes.
✔️ Dosage & Administration of Metformin Hydrochloride
  • The initial dose varies for type 2 diabetes and PCOS. Adjustments are made based on the patient's condition and response to treatment.
  • Contraindicated in severe renal impairment. Regular monitoring is essential for those at risk for renal impairment.
  • Take Met 500 with food to avoid nausea and abdominal pain. Consistency in timing is crucial for optimal benefits.
✔️ Interaction

Additive effects with sulfonylureas. Thiazide diuretics, corticosteroids, phenothiazines, oral contraceptives, sympathomimetics, niacin, calcium channel blockers, isoniazid, and ACE inhibitors may affect glycaemic control. Potential fatal interaction with iodinated contrast agents.

✔️ Contraindications

Avoid acute or chronic metabolic acidosis, renal failure, severe renal or hepatic impairment, dehydration, severe infection, shock, cardiac failure, congestive heart failure (CHF), insulin-dependent diabetes mellitus (IDDM), severe thyroid impairment, acute or chronic alcoholism, and conditions causing tissue hypoxia.

✔️ Metformin Hydrochloride during Pregnancy & Lactation

Pregnancy:

  • Uncontrolled diabetes during pregnancy (gestational or permanent) increases the risk of birth defects and perinatal mortality.
  • It is advised not to use metformin to treat diabetes when planning to become pregnant and during pregnancy.
  • Insulin is recommended during pregnancy to maintain blood sugar levels as close to normal as possible, reducing the risk of fetal malformations.

Breastfeeding:

  • Metformin is excreted in human milk.
  • No adverse reactions were observed in breastfed newborns/infants.
  • Limited data is available; breastfeeding during metformin treatment is not recommended.
  • The decision to continue breastfeeding should consider the benefits and potential risks of adverse effects on the child.
✔️ Precautions & Warnings

Exercise caution in patients with CHF, risk of lactic acid accumulation, and during stress-related states. Temporary discontinuation may be necessary for certain medical procedures.

✔️ Storage Conditions
  • Store MET 500mg Tablet below 25°C at a cool and dry place.
  • Protect it from direct sunlight and moisture.
  • Keep it out of reach of children and pets.
Frequently Asked Questions (FAQ)

Ans: Consume the medication after having food, following your doctor's prescription.

Ans: It usually does not cause sleepiness and is well-tolerated.

Ans: It is one of the primary medicines for managing high blood sugar levels, promoting blood sugar control.

Ans: Use the medication until you observe an improvement in your health conditions. Follow your doctor's guidance.

Ans: It can cause weight gain in some individuals. Consult your doctor for personalized advice.

Ans: Use the medication at the frequency prescribed by your doctor. Do not alter the dosage without consultation.

Ans: Store in a cool, dry place in its original packaging. Keep it out of reach of children and pets.

Ans: Take this medication after food, following the prescribed dosage.

Ans: MET 500 Tablet contains metformin as an active ingredient. It helps maintain balanced blood sugar levels and is used to treat Type 2 diabetes and PCOS.
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Check our pricing section for MET 500mg Tablet 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
ePharma reserves the right to make adjustments to pricing, Products and Service offerings for reasons including, but not limited to, changing market conditions, Product discontinuation, Product unavailability, manufacturer price changes, supplier price changes and errors in advertisements. All orders are subject to Product availability and the availability of Personnel to perform the Services. Therefore, Seller cannot guarantee that it will be able to fulfill Customer’s orders. If Services are being performed on a time and materials basis, any estimates provided by Seller are for planning purposes only.

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